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Results for “DNA Repair-Deficiency Disorders”

383 trials

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Showing 20 of 383 results

Not applicableUnknownNCT00929097
What this trial is testing

Implementation of Guidelines on Hereditary or Familial Colorectal Cancer

Who this might be right for
Colorectal Neoplasms, Hereditary Nonpolyposis
ZonMw: The Netherlands Organisation for Health Research and Development 300
Very early researchStudy completedNCT03832985
What this trial is testing

Pediatric Reporting of Adult-Onset Genomic Results

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeLynch SyndromeFamilial Hypercholesterolemia
Geisinger Clinic 427
Testing effectiveness (Phase 2)Study completedNCT02797977
What this trial is testing

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Who this might be right for
Advanced Solid Tumors
Sierra Oncology LLC - a GSK company 153
Not applicableNot Yet RecruitingNCT06772844
What this trial is testing

DYNAMICS-LYNCH：DNA Methylation Analysis in Stool for Screening of Lynch Syndrome-Associated Colorectal Cancer

Who this might be right for
Colorectal Cancer ScreeningLynch Syndrome
Sun Yat-sen University 400
Not applicableLooking for participantsNCT06898996
What this trial is testing

FITting Non-invasive Tests in Lynch Syndrome Surveillance

Who this might be right for
Colorectal Cancer
University of Chicago 400
Not applicableStudy completedNCT05471310
What this trial is testing

Videoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia

Who this might be right for
Ataxia TelangiectasiaDysmetria
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 5
Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Not applicableEnrolling By InvitationNCT06654128
What this trial is testing

The Yield of Artificial Intelligence (GI Genius) in Lynch Syndrome - A Randomized Tandem-colonoscopy Trial

Who this might be right for
Lynch Syndrome
Sheba Medical Center 100
Not applicableActive Not RecruitingNCT04145388
What this trial is testing

Family History Study on Cancer Risk

Who this might be right for
Lynch SyndromeColorectal CancerBreast Cancer+3 more
Kaiser Permanente 18,623
Not applicableStudy completedNCT00633607
What this trial is testing

Hereditary Colorectal and Associated Tumor Registry Study

Who this might be right for
Lynch SyndromeFAPHereditary Diffuse Gastric Cancer+2 more
University of Pittsburgh 114
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Not applicableLooking for participantsNCT02012699
What this trial is testing

Integrated Cancer Repository for Cancer Research

Who this might be right for
Pancreatic CancerThyroid CancerLung Cancer+47 more
University of Nebraska 999,999
Not applicableStudy completedNCT03609814
What this trial is testing

Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Who this might be right for
Hematologic MalignanciesNonmalignant DiseasesImmunodeficiencies+5 more
University of California, San Francisco 30
Large-scale testing (Phase 3)Study completedNCT00220766
What this trial is testing

Rapid Infusion of Immune Globulin Intravenous (Human) In Primary Immunodeficiency Patients

Who this might be right for
Immunologic Deficiency SyndromeAgammaglobulinemiaSevere Combined Immunodeficiency+2 more
Grifols Therapeutics LLC 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT03206086
What this trial is testing

Eltrombopag for People With Fanconi Anemia

Who this might be right for
Fanconi Anemia
National Heart, Lung, and Blood Institute (NHLBI) 25
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Testing effectiveness (Phase 2)Ended earlyNCT04779151
What this trial is testing

Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab

Who this might be right for
Urothelial Bladder CancerGastric AdenocarcinomaGastro-oesophageal Adenocarcinoma+5 more
Gustave Roussy, Cancer Campus, Grand Paris 51
Testing effectiveness (Phase 2)Study completedNCT02797964
What this trial is testing

A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

Who this might be right for
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Sierra Oncology LLC - a GSK company 107
Not applicableAvailableNCT01995305
What this trial is testing

Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents

Who this might be right for
Fanconi AnemiaAutosomal or Sex Linked Recessive Genetic DiseaseBone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases.+1 more
Xiaofan Zhu
Testing effectiveness (Phase 2)Study completedNCT04939662
What this trial is testing

Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects

Who this might be right for
Lung Cancer
Se-Hoon Lee 25
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