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Results for “DNA Repair-Deficiency Disorders”

391 trials

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Showing 20 of 391 results

Not applicableLooking for participantsNCT00055172
What this trial is testing

Genetic Basis of Immunodeficiency

Who this might be right for
Severe Combined Immunodeficiency
National Heart, Lung, and Blood Institute (NHLBI) 100
Not applicableStudy completedNCT00005892
What this trial is testing

Study of Allogeneic Bone Marrow Transplantation Following Cyclophosphamide and Radiotherapy in Patients With Myelodysplastic Syndrome and Acute Leukemia Related to Fanconi's Anemia

Who this might be right for
Fanconi's AnemiaMyelodysplastic SyndromesLeukemia, Nonlymphocytic, Acute+1 more
Fairview University Medical Center
Not applicableLooking for participantsNCT05495776
What this trial is testing

Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer

Who this might be right for
Colorectal CancerLynch SyndromeHereditary Colorectal Cancer+1 more
State Scientific Centre of Coloproctology, Russian Federation 2,500
Testing effectiveness (Phase 2)Study completedNCT03207347
What this trial is testing

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Who this might be right for
MesotheliomaUveal MelanomaRenal Cell Carcinoma+1 more
University of Florida 37
Not applicableStudy completedNCT01646112
What this trial is testing

Uncertain Genetic Test Results for Lynch Syndrome

Who this might be right for
HNPCC
National Human Genome Research Institute (NHGRI) 27
Testing effectiveness (Phase 2)Looking for participantsNCT07371663
What this trial is testing

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors

Who this might be right for
Solid CancersNSCLC (Advanced Non-small Cell Lung Cancer)Gastric (Stomach) Cancer+2 more
Beijing Tide Pharmaceutical Co., Ltd 266
Testing effectiveness (Phase 2)Looking for participantsNCT05086692
What this trial is testing

A Beta-only IL-2 ImmunoTherapY Study

Who this might be right for
Advanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more
Medicenna Therapeutics, Inc. 115
Not applicableStudy completedNCT01823471
What this trial is testing

I-Scan For Colon Polyp Detection In HNPCC

Who this might be right for
Hereditary Non-polyposis Colon CarcinomaHNPCCLynch Syndrome
Universitaire Ziekenhuizen KU Leuven 70
Early research (Phase 1)UnknownNCT05531890
What this trial is testing

Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects

Who this might be right for
Ataxia Telangiectasia
Grace Therapeutics Inc. 48
Not applicableStudy completedNCT00313755
What this trial is testing

Magnification Narrow Band Imaging Colonoscopy for Hereditary Non-Polyposis Colorectal Cancer Surveillance

Who this might be right for
Colorectal Neoplasms, Hereditary Nonpolyposis
London North West Healthcare NHS Trust 60
Testing effectiveness (Phase 2)Ended earlyNCT04155190
What this trial is testing

Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC

Who this might be right for
Recurrent Basal Cell Carcinoma
Sol-Gel Technologies, Ltd. 47
Not applicableStudy completedNCT00001255
What this trial is testing

Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study

Who this might be right for
Severe Combined Immunodeficiency
National Human Genome Research Institute (NHGRI) 10
Testing effectiveness (Phase 2)Study completedNCT00479115
What this trial is testing

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100

Who this might be right for
Fanconi Anemia
Children's Hospital Medical Center, Cincinnati 1
Not applicableUnknownNCT03294343
What this trial is testing

Risk-Reducing Surgeries for Hereditary Ovarian Cancer

Who this might be right for
Hereditary Breast and Ovarian Cancer SyndromeColorectal Neoplasms, Hereditary NonpolyposisOvariectomy+1 more
Lei Li 600
Not applicableStudy completedNCT00043225
What this trial is testing

The Role of Bacteria and Genetic Variations in Cystic Fibrosis

Who this might be right for
Psuedomas InfectionCystic Fibrosis
National Heart, Lung, and Blood Institute (NHLBI) 76
Early research (Phase 1)Study completedNCT00008450
What this trial is testing

Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

Who this might be right for
Adenosine Deaminase DeficiencyAutosomal Recessive DisorderImmune System Disorder+4 more
Fred Hutchinson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT02931071
What this trial is testing

Clinical Phase II Trial to Evaluate CD34+ Cells Mobilization and Collection in Patients With Fanconi Anemia for Subsequent Transduction With a Lentiviral Vector Carring FANCA Gene. FANCOSTEM-1

Who this might be right for
Fanconi Anemia
Hospital Universitari Vall d'Hebron Research Institute 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT03228667
What this trial is testing

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerUrothelial Carcinoma+10 more
ImmunityBio, Inc. 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT01821781
What this trial is testing

Immune Disorder HSCT Protocol

Who this might be right for
Immune Deficiency DisordersSevere Combined ImmunodeficiencyChronic Granulomatous Disease+11 more
Washington University School of Medicine 20
Not applicableLooking for participantsNCT04982744
What this trial is testing

Registry of Li Fraumeni and Li Fraumeni Like Syndromes

Who this might be right for
Li-Fraumeni SyndromeLi-Fraumeni-Like Syndrome
Istituto Ortopedico Rizzoli 200
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