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Results for “De-escalation”

268 trials

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Showing 20 of 268 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07189325
What this trial is testing

A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple Sclerosis

Who this might be right for
Relapsing-Remitting Multiple Sclerosis (RRMS)Anti-CD20 Therapy
University Hospital, Montpellier 250
Testing effectiveness (Phase 2)Active Not RecruitingNCT05923190
What this trial is testing

Enfortumab Vedotin Schedule De-escalation in Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial CarcinomaMetastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Fox Chase Cancer Center 60
Large-scale testing (Phase 3)Looking for participantsNCT06704945
What this trial is testing

No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy

Who this might be right for
Breast CancerNeoadjuvant TherapySentinel Lymph Node Biopsy
Seoul National University Hospital 464
Early research (Phase 1)Study completedNCT00990054
What this trial is testing

Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Genzyme, a Sanofi Company 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07271992
What this trial is testing

TREND-02 - a Phase II Exploratory De-escalation Trial of Neoadjuvant Sacituzumab Govitecan Plus Tislelizumab (SG/I) in Early Triple-negative Breast Cancer

Who this might be right for
TNBC, Triple Negative Breast Cancer
First Hospital of China Medical University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07643584
What this trial is testing

De-Escalation of Axillary Management in Advanced Nodal Disease

Who this might be right for
Breast Cancer
University of Kansas Medical Center 120
Large-scale testing (Phase 3)Looking for participantsNCT06653348
What this trial is testing

Ticagrelor Based De-Escalation of Dual Antiplatelet Therapy in Ischemic Stroke

Who this might be right for
Ischemic StrokeTransient Ischemic Attack
Mazandaran University of Medical Sciences 100
Not applicableLooking for participantsNCT06238297
What this trial is testing

Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia

Who this might be right for
Pneumonia, Bacterial
University of Bari Aldo Moro 76
Not applicableNot Yet RecruitingNCT06900582
What this trial is testing

SENTInel Node Mapping Versus Comprehensive Lymphadenectomy in p53-Mutated Endometrial Cancer: A Non-Inferiority Randomized Trial

Who this might be right for
LymphadenectomyEndometrial CancerGene, p53+1 more
University Hospital, Strasbourg, France 374
Testing effectiveness (Phase 2)Study completedNCT01839916
What this trial is testing

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)+61 more
University of Chicago 77
Early research (Phase 1)Study completedNCT00004871
What this trial is testing

Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Not applicableNot Yet RecruitingNCT07098507
What this trial is testing

De-escalation in Axillary Surgery for Early-stage Breast Cancer

Who this might be right for
Omitting Sentinel Lymph Node Biopsy in Early-stage Breast Cancer
Clinical Hospital Center Rijeka 620
Not applicableLooking for participantsNCT03396718
What this trial is testing

De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell Carcinomas

Who this might be right for
Head-and-neck Squamous Cell Carcinoma
Technische Universität Dresden 304
Testing effectiveness (Phase 2)Looking for participantsNCT06563362
What this trial is testing

Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell Carcinoma

Who this might be right for
Oropharynx Cancer
University of Zurich 120
Not applicableUnknownNCT04158518
What this trial is testing

De-escalation Protocols in Locoregionally Advanced Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Carcinoma
Chaosu Hu 118
Testing effectiveness (Phase 2)Study completedNCT03917654
What this trial is testing

Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali

Who this might be right for
Malaria
National Institute of Allergy and Infectious Diseases (NIAID) 1,301
Testing effectiveness (Phase 2)Study completedNCT01229176
What this trial is testing

Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adults, Children, Older Infants and Infants

Who this might be right for
Typhoid Fever
Novartis 200
Testing effectiveness (Phase 2)Looking for participantsNCT04444869
What this trial is testing

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

Who this might be right for
Cancer of the Head and NeckOropharynx CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Missouri-Columbia 28
Large-scale testing (Phase 3)Not Yet RecruitingNCT06278896
What this trial is testing

Early Neutropenic Fever De-escalation of Antibiotics Study

Who this might be right for
Hematologic MalignancyFebrile NeutropeniaAntibiotic Stewardship
Brigham and Women's Hospital 260
Not applicableNot Yet RecruitingNCT06039956
What this trial is testing

De-escalating Axillary Surgery in Breast Cancer Patients in Nigeria

Who this might be right for
Breast CancerAxilla; Breast
Nova Scotia Health Authority 100
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