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Results for “Diffuse Cutaneous Systemic Sclerosis”

87 trials

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Showing 20 of 87 results

Early research (Phase 1)Study completedNCT02426229
What this trial is testing

Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma

Who this might be right for
SclerodermaInterstitial Lung Disease
Medical University of South Carolina 15
Large-scale testing (Phase 3)Active Not RecruitingNCT05925803
What this trial is testing

Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)

Who this might be right for
Systemic SclerosisScleroderma
AstraZeneca 314
Testing effectiveness (Phase 2)Ended earlyNCT03919799
What this trial is testing

KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
System; SclerosisDiffuse Cutaneous Systemic Sclerosis
Kadmon, a Sanofi Company 36
Testing effectiveness (Phase 2)WithdrawnNCT02588625
What this trial is testing

A Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc)

Who this might be right for
Scleroderma
Bristol-Myers Squibb
Testing effectiveness (Phase 2)Looking for participantsNCT03844061
What this trial is testing

Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Hospital for Special Surgery, New York 30
Testing effectiveness (Phase 2)Study completedNCT02161406
What this trial is testing

Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Dinesh Khanna, MD, MS 88
Testing effectiveness (Phase 2)Study completedNCT03041025
What this trial is testing

Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Systemic
GlaxoSmithKline 35
Not applicableStudy completedNCT02339441
What this trial is testing

Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Early Diffuse Cutaneous Systemic Sclerosis
University of Manchester 320
Post-approval studies (Phase 4)Study completedNCT07472166
What this trial is testing

Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

Who this might be right for
Scleroderma, Systemic
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 34
Large-scale testing (Phase 3)Looking for participantsNCT06716606
What this trial is testing

Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)

Who this might be right for
Connective Tissue Diseases
GlaxoSmithKline 514
Post-approval studies (Phase 4)Study completedNCT04464434
What this trial is testing

Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic SclerosisSystemic Scleroses, DiffuseScleroderma+5 more
UMC Utrecht 60
Not applicableWithdrawnNCT02531009
What this trial is testing

Systemic Sclerosis Clinical and Biomarker Study

Who this might be right for
HealthySystemic Sclerosis
Biogen
Testing effectiveness (Phase 2)Study completedNCT01670565
What this trial is testing

Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Hospital for Special Surgery, New York 20
Not applicableUnknownNCT05168215
What this trial is testing

Effectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease.

Who this might be right for
SclerodermaDigital UlcerAutoimmune Diseases+2 more
Elpen Pharmaceutical Co. Inc. 300
Not applicableStudy completedNCT01093885
What this trial is testing

Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis

Who this might be right for
Systemic SclerosisScleroderma
University of Pennsylvania 15
Testing effectiveness (Phase 2)Study completedNCT00479934
What this trial is testing

Efficacy and Safety of Imatinib in Scleroderma

Who this might be right for
Scleroderma, LocalizedScleroderma, Systemic
University Hospital, Bordeaux 28
Testing effectiveness (Phase 2)UnknownNCT00769028
What this trial is testing

AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Daval International Limited 20
Not applicableStudy completedNCT00476801
What this trial is testing

UVA1 Light for Treatment of Scleroderma and Similar Conditions

Who this might be right for
SclerodermaKeloidsOther Fibrosing Conditions
University of Michigan 27
Testing effectiveness (Phase 2)Study completedNCT02921971
What this trial is testing

Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis

Who this might be right for
Systemic Sclerosis
Sanofi 97
Not applicableNot Yet RecruitingNCT07642297
What this trial is testing

TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)

Who this might be right for
Systemic Sclerosis (SSc)Diffuse Cutaneous Systemic SclerosisSkin Fibrosis
Fondazione Policlinico Universitario Campus Bio-Medico 20
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