Early research (Phase 1)Study completedNCT00178464What this trial is testingAspirin Prophylaxis in Sickle Cell DiseaseWho this might be right forSickle Cell Disease University of Rochester 11
Early research (Phase 1)Study completedNCT02237586What this trial is testingEffect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ ChallengeWho this might be right forPlasmodium Falciparum MalariaMalaria Sanaria Inc. 25
Not applicableStudy completedNCT02561312What this trial is testingComparison of Two Methods of Transfusion for Stroke Prevention in Sickle CellWho this might be right forAnemia, Sickle CellSickling Disorder Due to Hemoglobin S Chattanooga-Hamilton County Hospital Authority 9
Early research (Phase 1)Looking for participantsNCT07015684What this trial is testing131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)Who this might be right forSickling Disorder Due to Hemoglobin S Columbia University 24
Not applicableStudy completedNCT03984500What this trial is testingA Program to Increase Sickle Cell Trait Knowledge Among Parent of Young Children Identified in Newborn ScreeningWho this might be right forSickle Cell Trait Susan Creary 74
Not applicableUnknownNCT04090268What this trial is testingPrecision Exercise in Children With Malignant HemopathiesWho this might be right forLeukemia, Myeloid, AcuteLeukemia, B-cellLeukemia, T Cell+5 more University of Milano Bicocca 380
Not applicableUnknownNCT01891877What this trial is testingSickle Cell Trait in Football PlayersWho this might be right forSickle Cell Trait University of South Florida 20
Not applicableStudy completedNCT03985501What this trial is testingDREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass SpectrometryWho this might be right forSickle Cell DiseaseInfant, Newborn, DiseaseDrepanocytosis Hospices Civils de Lyon 1,431
Testing effectiveness (Phase 2)Study completedNCT04987489What this trial is testingEtavopivat in Patients With Thalassemia or Sickle Cell DiseaseWho this might be right forSickle Cell DiseaseThalassemia Forma Therapeutics, Inc. 53
Not applicableStudy completedNCT04244240What this trial is testingLinks Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.Who this might be right forSickle Cell DiseaseDrepanocytosis Hospices Civils de Lyon 19
Not applicableUnknownNCT04845022What this trial is testingIncidence of Snakebite Associated Thrombotic Microangiopathy & Role of Peripheral Blood Smear as a Predictor of Clinical OutcomeWho this might be right forSNAKEBITETHROMBOTIC MICROANGIOPATHYSCHISTOCYTES Jubilee Mission Medical College and Research Institute 81
Early research (Phase 1)Study completedNCT05036512What this trial is testingEvaluate GBT021601 in Single and Multiple Doses in Healthy ParticipantsWho this might be right forSickle Cell Disease Pfizer 129
Not applicableLooking for participantsNCT07064174What this trial is testingSickle Cell Kidney BiorepositoryWho this might be right forSickle Cell TraitSickle Cell Disease (SCD)Chronic Kidney Disease University of Texas Southwestern Medical Center 800
Large-scale testing (Phase 3)Ended earlyNCT04927247What this trial is testingA Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive CrisesWho this might be right forSickle Cell DiseaseVaso-occlusive CrisisVaso-occlusive Pain Episode in Sickle Cell Disease Pfizer 72
Early research (Phase 1)Looking for participantsNCT05904093What this trial is testingStudy to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseWho this might be right forSickle Cell DisordersSickle Cell DiseaseHemoglobin S+2 more National Heart, Lung, and Blood Institute (NHLBI) 35
Not applicableStudy completedNCT00720317What this trial is testingDiabetic Retinopathy and Sickle TraitWho this might be right forDiabetic RetinopathySickle Cell Trait Medical University of South Carolina 48
Not applicableNot Yet RecruitingNCT07168447What this trial is testingTransfusion Exchanges and Cognition in Sickle Cell DiseaseWho this might be right forDrepanocytosisChronic Neurological Deficiency Centre Hospitalier St Anne 85
Testing effectiveness (Phase 2)Ended earlyNCT06078696What this trial is testingSiplizumab for Sickle Cell Disease TransplantWho this might be right forAnemia, Sickle Cell Columbia University 1
Post-approval studies (Phase 4)Study completedNCT04662931What this trial is testingAn Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 140
Large-scale testing (Phase 3)Active Not RecruitingNCT03814746What this trial is testingStudy of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease PatientsWho this might be right forSickle Cell Disease (SCD) Novartis Pharmaceuticals 254