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Results for “Endothelin”

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Showing 20 of 0 results

Not applicableStudy completedNCT02062346
What this trial is testing

Endothelin Antagonism in ANCA Vasculitis

Who this might be right for
Vasculitis
University of Edinburgh 64
Testing effectiveness (Phase 2)Study completedNCT00318175
What this trial is testing

Effect of Bosentan on Skin Fibrosis in Patients With Systemic Sclerosis

Who this might be right for
Systemic SclerodermaSkin FibrosisHand Functionality
Heinrich-Heine University, Duesseldorf 10
Testing effectiveness (Phase 2)Ended earlyNCT00832507
What this trial is testing

Study of Cicletanine for Pulmonary Arterial Hypertension (PAH)

Who this might be right for
Pulmonary Arterial Hypertension
Gilead Sciences 162
Post-approval studies (Phase 4)UnknownNCT00637065
What this trial is testing

Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment Study

Who this might be right for
Pulmonary HypertensionInterstitial Lung DiseaseIdiopathic Pulmonary Fibrosis+1 more
Royal Brompton & Harefield NHS Foundation Trust 48
Early research (Phase 1)WithdrawnNCT01119417
What this trial is testing

The Role of Endothelin in the Supine Hypertension of Autonomic Failure

Who this might be right for
HypertensionPure Autonomic FailureMultiple System Atrophy
Vanderbilt University
Large-scale testing (Phase 3)Study completedNCT00554229
What this trial is testing

A Phase III Trial of ZD4054 (Zibotentan) (Endothelin A Antagonist) in Hormone Resistant Prostate Cancer With Bone Metastases

Who this might be right for
Prostate Cancer
AstraZeneca 896
Large-scale testing (Phase 3)Active Not RecruitingNCT06087835
What this trial is testing

Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)

Who this might be right for
Chronic Kidney Disease With High Proteinuria
AstraZeneca 1,835
Not applicableStudy completedNCT00452283
What this trial is testing

Changes in Eye Pressure and Anterior Chamber Depth With Oral Endothelin Antagonist Therapy

Who this might be right for
GlaucomaPulmonary Hypertension
University of Colorado, Denver 23
Large-scale testing (Phase 3)Study completedNCT01224210
What this trial is testing

Ambrisentan in Patients With Porto-pulmonary Hypertension A Multicenter Open Label Trial

Who this might be right for
Portopulmonary Hypertension
Tufts Medical Center 30
Large-scale testing (Phase 3)Ended earlyNCT00795639
What this trial is testing

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Who this might be right for
Pulmonary Arterial HypertensionPulmonary Hypertension
Pfizer 183
Not applicableWithdrawnNCT02309463
What this trial is testing

Correlation of LONGterm Wrist ACTigraphy Recorded Physical Performance & 6-minute Walk Distance in Patients With Pulmonary Arterial Hypertension

Who this might be right for
Pulmonary Arterial Hypertension
Actelion
Testing effectiveness (Phase 2)UnknownNCT01617746
What this trial is testing

Examination of the Bronchoprotective Effect of Endothelin Receptor Blockade in Asthma

Who this might be right for
Asthma
University of Glasgow 18
Early research (Phase 1)Study completedNCT00722215
What this trial is testing

Endothelin Receptor Antagonism in Proteinuric Nephropathy

Who this might be right for
Chronic Kidney DiseaseProteinuria
University of Edinburgh 22
Not applicableStudy completedNCT00814281
What this trial is testing

Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?

Who this might be right for
Airway Inflammation
Marywood University 24
Early research (Phase 1)Study completedNCT00613691
What this trial is testing

A Phase I, Open-label, Ascending Dose Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Endothelin B Agonist, SPI-1620, in Patients With Recurrent or Progressive Carcinoma

Who this might be right for
Carcinoma
Spectrum Pharmaceuticals, Inc 36
Testing effectiveness (Phase 2)Study completedNCT01662037
What this trial is testing

Bosentan Therapy in Children With Functional Single Ventricle

Who this might be right for
Congenital Heart DefectsFunctional Single Ventricle
Shanghai Jiao Tong University School of Medicine 34
Post-approval studies (Phase 4)UnknownNCT03229694
What this trial is testing

The Effect of Tracleer on Tourniquet-associated Hypertension

Who this might be right for
TourniquetsHypertensionBosentan
Xuzhou Medical University 80
Testing effectiveness (Phase 2)Study completedNCT04097314
What this trial is testing

Precision Medicine With Zibotentan in Microvascular Angina

Who this might be right for
Microvascular Angina
NHS Greater Glasgow and Clyde 225
Not applicableUnknownNCT04732650
What this trial is testing

Real World Difference After Changing Medication From Nonselective to Selective Endothelin Receptor Antagonist in Stable Eisenmenger Syndrome

Who this might be right for
Eisenmenger Complex
Samsung Medical Center 40
Very early researchLooking for participantsNCT04449198
What this trial is testing

Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1

Who this might be right for
Type 1 Diabetes
Augusta University 24
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