Not applicableUnknownNCT04914078What this trial is testingSevere Asthma Exacerbations and Mepolizumab TreatmentWho this might be right forSevere Asthma Università degli Studi di Ferrara 70
Testing effectiveness (Phase 2)Study completedNCT04046939What this trial is testingDexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic AsthmaWho this might be right forEosinophilic AsthmaAsthma Knopp Biosciences 534
Not applicableUnknownNCT05814484What this trial is testingRole of Inhaler Adherence and Blood Eosinophil Count in Exacerbations of COPDWho this might be right forChronic Obstructive Pulmonary DiseaseAdherence, Treatment University of Leicester 104
Post-approval studies (Phase 4)Not Yet RecruitingNCT07587658What this trial is testingThis After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring HospitalizationWho this might be right forChronic Obstructive Pulmonary Disease (COPD) Regeneron Pharmaceuticals 754
Testing effectiveness (Phase 2)Ended earlyNCT00402948What this trial is testingSafety and Efficacy of Two Dosages of Inhaled TPI ASM8 Compared to Placebo in Mild to Moderate Asthmatic PatientsWho this might be right forAsthma Syntara 10
Not applicableNot Yet RecruitingNCT07730047What this trial is testingNLR, ELR and SII Index as Biomarkers of Asthma ControlWho this might be right forAsthma Control Shaimaa Ali Mohammed 140
Post-approval studies (Phase 4)Study completedNCT04481555What this trial is testingEosinophil-guided Reduction of Inhaled CorticosteroidsWho this might be right forCOPDInhaled CorticosteroidAzithromycin+2 more Chronic Obstructive Pulmonary Disease Trial Network, Denmark 444
Large-scale testing (Phase 3)WithdrawnNCT05152563What this trial is testingAssess Subcutaneous AK002 in Eosinophilic Gastritis and/or Eosinophilic DuodenitisWho this might be right forEosinophilic GastritisEosinophilic Duodenitis Allakos Inc.
Post-approval studies (Phase 4)UnknownNCT04319705What this trial is testingAnti-viral Effects of Azithromycin in Patients With Asthma and COPDWho this might be right forAsthmaCOPDExacerbation Copd+5 more Bispebjerg Hospital 100
Not applicableStudy completedNCT05672030What this trial is testingRole of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNPWho this might be right forNasal PolypsAspirin-exacerbated Respiratory Disease Brigham and Women's Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT01821898What this trial is testingEosinophilic Esophagitis Clinical Therapy Comparison TrialWho this might be right forEosinophilic Esophagitis Baylor College of Medicine 3
Not applicableWithdrawnNCT00180765What this trial is testingRegulation of the Release of Inflammatory Mediators From Blood LeukocytesWho this might be right forChronic Obstructive Airway DiseaseHealthy Volunteers Imperial College London
Post-approval studies (Phase 4)Study completedNCT02857842What this trial is testingCorticosteroid Reduction in COPDWho this might be right forLung Diseases, ObstructiveBlood Eosinophil CountGlucocorticoids+2 more Chronic Obstructive Pulmonary Disease Trial Network, Denmark 318
Not applicableUnknownNCT02014610What this trial is testingWhite Blood Cell Counts and Onset of Cardiovascular Diseases: a CALIBER StudyWho this might be right forAbdominal Aortic AneurysmCoronary Artery DiseaseStroke+2 more University College, London 800,000
Not applicableUnknownNCT04888910What this trial is testingNovel Inflammatory Markers in Different Phenotypes of Severe AsthmaWho this might be right forAsthmaNasal Polyps University of Pisa 80
Large-scale testing (Phase 3)Study completedNCT04133909What this trial is testingMepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil LevelWho this might be right forPulmonary Disease, Chronic Obstructive GlaxoSmithKline 806
Large-scale testing (Phase 3)Study completedNCT02135692What this trial is testingA Phase 3a, Repeat Dose, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic SubjectsWho this might be right forAsthma GlaxoSmithKline 339
Not applicableEnded earlyNCT03679299What this trial is testingVascular Implications of a Naturally Occurring Asthma ExacerbationWho this might be right forAsthmaInflammationCardiovascular Risk Factor University of Alberta 3
Not applicableActive Not RecruitingNCT07390669What this trial is testingOptimAIR: Towards Right Care in Asthma Through Point-of-care Phenotyping, Guideline-based Assessment and Management Optimalisation Using the AsthmaOptimiser in Primary CareWho this might be right forAsthma Control General Practitioners Research Institute 746
Not applicableUnknownNCT05847452What this trial is testingBeyond the Eosinophil: Understanding the Impact of Eosinophil Depletion on T2 Inflammation. (BEUTI)Who this might be right forAsthma Guy's and St Thomas' NHS Foundation Trust 12