Early research (Phase 1)Not Yet RecruitingNCT05043181What this trial is testingExosome-based Nanoplatform for Ldlr mRNA Delivery in FHWho this might be right forFamilial Hypercholesterolemia Tang-Du Hospital 30
Not applicableUnknownNCT03984149What this trial is testingLipa Gene Mutation in PED-LIPIGEN (Pediatric FH Subjects)Who this might be right forLysosomal Acid Lipase Deficiency Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 1,000
Not applicableUnknownNCT02489253What this trial is testingAtherosclerosis in Familial HypercholesterolemiaWho this might be right forFamilial Hypercholesterolemia University College, London 100
Not applicableLooking for participantsNCT02009345What this trial is testingFamilial Hypercholesterolemia Canada / Hypercholesterolemie Familiale CanadaWho this might be right forFamilial HypercholesterolemiaLipid Disorder McGill University Health Centre/Research Institute of the McGill University Health Centre 6,000
Testing effectiveness (Phase 2)Study completedNCT00477594What this trial is testingOpen Label Extension of ISIS 301012 (Mipomersen) to Treat Familial HypercholesterolemiaWho this might be right forLipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more Kastle Therapeutics, LLC 21
Post-approval studies (Phase 4)Study completedNCT00916643What this trial is testingLow-Density Lipoprotein (LDL) Apheresis Using H.E.L.P. TherapyWho this might be right forFamilial Hypercholesterolemia B. Braun Medical Inc. 113
Large-scale testing (Phase 3)Study completedNCT06005597What this trial is testingStudy of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying TherapiesWho this might be right forDyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more NewAmsterdam Pharma 407
Not applicableWithdrawnNCT02399852What this trial is testingEffects of Lomitapide on Carotid and Aortic AtherosclerosisWho this might be right forHomozygous Familial Hypercholesterolemia Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT00607373What this trial is testingStudy to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial HypercholesterolemiaWho this might be right forLipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more Kastle Therapeutics, LLC 51
Early research (Phase 1)Study completedNCT05398029What this trial is testingVERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular DiseaseWho this might be right forHeterozygous Familial HypercholesterolemiaAtherosclerotic Cardiovascular DiseaseHypercholesterolemia Verve Therapeutics, Inc. 13
Large-scale testing (Phase 3)Study completedNCT00116870What this trial is testingMARS - Monitored Atherosclerosis Regression StudyWho this might be right forAtherosclerosisCoronary Artery Disease Merck Sharp & Dohme LLC 270
Early research (Phase 1)Looking for participantsNCT06164730What this trial is testingVERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery DiseaseWho this might be right forHeterozygous Familial HypercholesterolemiaPremature Coronary Heart Disease Verve Therapeutics, Inc. 85
Not applicableLooking for participantsNCT02208869What this trial is testingRussian Familial Hypercholesterolemia RegistryWho this might be right forFamilial Hypercholesterolemia Russian Cardiology Research and Production Center 1,000
Not applicableStudy completedNCT02726100What this trial is testingSMARTHealth Diabetes in China Using Lay Family Health PromotersWho this might be right forDiabetes Mellitus, Type 2HypertensionDyslipidemias The George Institute for Global Health, China 2,073
Testing effectiveness (Phase 2)Study completedNCT02098278What this trial is testingPilot Study To Assess CAT-2003 in Patients With ChylomicronemiaWho this might be right forLipoprotein Lipase Deficiency, FamilialHyperlipoproteinemia Type IChylomicronemia, Familial+1 more Catabasis Pharmaceuticals 13
Not applicableStudy completedNCT04737720What this trial is testingIntravenous ACP-501 for Familial LCAT Deficiency (rhLCAT)Who this might be right forFamilial LCAT Deficiency National Heart, Lung, and Blood Institute (NHLBI) 1
Not applicableUnknownNCT04688684What this trial is testingThe Emirates Heart Health Project: A Family-based Diet and Exercise Intervention in Obese and Overweight PatientsWho this might be right forOverweight and ObesityCardiovascular Risk Factor United Arab Emirates University 80
Not applicableUnknownNCT04080050What this trial is testingA Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501Who this might be right forHomozygous Familial Hypercholesterolemia (HoFH) REGENXBIO Inc. 8
Not applicableUnknownNCT00945217What this trial is testingThe Roles of SAH Gene Family in Athrogenic Dyslipidemia in Postmenopausal WomenWho this might be right forDisorder Associated With Menstruation and/or MenopauseDyslipidemia Taipei Veterans General Hospital, Taiwan 660
Testing effectiveness (Phase 2)Study completedNCT01412034What this trial is testingEffect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) SubjectsWho this might be right forHomozygous Familial Hypercholesterolemia Cerenis Therapeutics, SA 23