Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “First Line Metastatic Colorectal Cancer”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT04456699
What this trial is testing

Efficacy and Safety of Olaparib (MK-7339) With or Without Bevacizumab Compared to Bevacizumab With a Fluoropyrimidine in Unresectable or Metastatic Colorectal Cancer (CRC) (MK-7339-003/LYNK-003)

Who this might be right for
Metastatic Colorectal Cancer
Merck Sharp & Dohme LLC 335
Testing effectiveness (Phase 2)Study completedNCT03584711
What this trial is testing

FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation

Who this might be right for
Metastatic Colorectal Cancer
Federation Francophone de Cancerologie Digestive 118
Large-scale testing (Phase 3)Ended earlyNCT03426371
What this trial is testing

Epidermal Growth Factor Receptor (EGFR) Antagonist Chimeric Anti-EGFR Monoclonal Antibody Trial

Who this might be right for
Metastatic Colorectal Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 52
Large-scale testing (Phase 3)Ended earlyNCT00720512
What this trial is testing

Second-Line Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Who Have Received First-Line Chemotherapy and Bevacizumab

Who this might be right for
Colorectal Cancer
Gruppo Oncologico del Nord-Ovest 184
Large-scale testing (Phase 3)UnknownNCT04262635
What this trial is testing

Cetuximab Plus Capecitabine as Maintenance Treatment in RAS and BRAF wt Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Sun Yat-sen University 80
Large-scale testing (Phase 3)Looking for participantsNCT07462143
What this trial is testing

A Phase Ⅱ/Ⅲ Clinical Trial of RC148 Plus Chemotherapy as 1L Therapy for Unresectable or Metastatic Colorectal Cancer

Who this might be right for
Colorectal (Colon or Rectal) Cancer
RemeGen Co., Ltd. 80
Large-scale testing (Phase 3)Looking for participantsNCT07389265
What this trial is testing

Continuation of Cetuximab Beyond First-Line Progression in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
University of Campania Luigi Vanvitelli 480
Not applicableStudy completedNCT01791140
What this trial is testing

BEVERLY-C: An Observational Study of Avastin (Bevacizumab) in First-Line Treatment in Elderly Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 3
Not applicableStudy completedNCT01555762
What this trial is testing

An Observational Study of Avastin in First Line in Elderly Patients With Metastatic Colorectal Cancer (CASSIOPEE)

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 402
Large-scale testing (Phase 3)UnknownNCT00433927
What this trial is testing

5-FU, Folinic Acid and Irinotecan (FOLFIRI) Plus Cetuximab Versus FOLFIRI Plus Bevacizumab in First Line Treatment Colorectal Cancer (CRC)

Who this might be right for
Neoplasm MetastasisColorectal Cancer
PD Dr. med. Volker Heinemann 568
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06423937
What this trial is testing

Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 129
Large-scale testing (Phase 3)UnknownNCT05362617
What this trial is testing

MFOLXOX6 Versus FOLFIRI for Colorectal Patients Recurrence After Oxaplatin Based Adjuvant Chemotherapy

Who this might be right for
Metastatic Colorectal Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine 328
Large-scale testing (Phase 3)Study completedNCT00642577
What this trial is testing

Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer.

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 214
Testing effectiveness (Phase 2)Active Not RecruitingNCT01531595
What this trial is testing

Study of Bevacizumab in Combination with Alternating XELIRI and XELOX in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Pia Osterlund 100
Post-approval studies (Phase 4)Not Yet RecruitingNCT07446465
What this trial is testing

FOLFOX Chemotherapy Combined With Fruquintinib and Serplulimab as First-Line Conversion Therapy for Initially Unresectable pMMR/MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer (Locally Advanced or Metastatic)Colorectal Cancer Microsatellite Stable (MSS)
Ye Xu 42
Testing effectiveness (Phase 2)Looking for participantsNCT05007132
What this trial is testing

Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Dominik Paul Modest 153
Testing effectiveness (Phase 2)UnknownNCT04296019
What this trial is testing

Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer

Who this might be right for
Colo-rectal Cancer
Shanghai Zhongshan Hospital 110
Not applicableStudy completedNCT03532711
What this trial is testing

Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal CancerChemotherapy EffectBiomarker
Fudan University 264
Very early researchLooking for participantsNCT07627191
What this trial is testing

GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer

Who this might be right for
Pancreatic CancerColorectal CancerHepatocellular Carcinoma
University of Arizona 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT07512674
What this trial is testing

Modified Short-Course Radiotherapy Combined With Immunochemotherapy and Targeted Therapy as First-Line Treatment for MSS Metastatic Colorectal Cancer

Who this might be right for
Patients With Initially Unresectable MSS-type Advanced Colorectal Cancer With Liver and/or Lung and Peritoneal Metastasis
Sir Run Run Shaw Hospital 33
Next Page