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Results for “Genetic Mutations”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT07432880
What this trial is testing

A Prospective Study of Pediatric Participants up to 16 Years of Age With Methylmalonic Acidemia (MMA) Due to Mutations in the MMUT Gene

Who this might be right for
Methylmalonic Acidemia (MMA)
Genespire Srl 30
Not applicableStudy completedNCT02047903
What this trial is testing

GIOTRIF in First Line Therapy of Advanced NSCLC With EGFR-mutations

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 161
Large-scale testing (Phase 3)Study completedNCT03293524
What this trial is testing

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 98
Testing effectiveness (Phase 2)Study completedNCT01078662
What this trial is testing

Open Label Study to Assess Efficacy and Safety of Olaparib in Confirmed Genetic BRCA1 or BRCA2 Mutation Pats

Who this might be right for
OvarianBreastProstate+2 more
AstraZeneca 298
Not applicableApproved For MarketingNCT04702360
What this trial is testing

ELX/TEZ/IVA Expanded Access Program for Cystic Fibrosis (CF) Patients With at Least One F508del Mutation

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06275620
What this trial is testing

A Study Comparing Two Doses of AGTC-501 in Male Participants With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (DAWN)

Who this might be right for
X-Linked Retinitis Pigmentosa
Beacon Therapeutics 24
Early research (Phase 1)UnknownNCT06362980
What this trial is testing

A Study With BPI-1178 and Osimertinib in Advanced Non-small Cell Lung Cancer Patients With EGFR Mutations

Who this might be right for
NSCLC
National Cancer Center, China 20
Early research (Phase 1)Study completedNCT04967079
What this trial is testing

Trametinib Plus Anlotinib in Non-G12C KRAS-Mutant NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
Shanghai Chest Hospital 33
Not applicableLooking for participantsNCT04367246
What this trial is testing

Li-Fraumeni Syndrome/TP53 Biobank

Who this might be right for
Li-Fraumeni SyndromeLi-Fraumeni-Like Syndrome
Abramson Cancer Center at Penn Medicine 300
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07681778
What this trial is testing

Safety and Tolerability of Subretinal OPGx-RDH12-1001 for LCA-Associated Inherited Retinal Degeneration (LCA-IRD)

Who this might be right for
Leber Congenital AmaurosisLeber Congenital Amaurosis (LCA)
Opus Genetics, Inc 10
Not applicableStudy completedNCT00747760
What this trial is testing

TSH Receptor Mutations Among a Consanguineous Community

Who this might be right for
Hypothyroidism
HaEmek Medical Center, Israel 209
Large-scale testing (Phase 3)Ended earlyNCT02090959
What this trial is testing

An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy

Who this might be right for
Muscular Dystrophy, DuchenneMuscular DystrophiesMuscular Disorders, Atrophic+6 more
PTC Therapeutics 219
Not applicableLooking for participantsNCT06311708
What this trial is testing

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Who this might be right for
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics 200
Testing effectiveness (Phase 2)Looking for participantsNCT07507760
What this trial is testing

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
PETHEMA Foundation 50
Not applicableStudy completedNCT00002924
What this trial is testing

Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy

Who this might be right for
Prostate Cancer
Alliance for Clinical Trials in Oncology 184
Large-scale testing (Phase 3)Study completedNCT01807923
What this trial is testing

Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation

Who this might be right for
Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
Vertex Pharmaceuticals Incorporated 559
Testing effectiveness (Phase 2)Study completedNCT02707562
What this trial is testing

Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation)

Who this might be right for
Cystic Fibrosis
Lakefront Biotherapeutics NV 26
Testing effectiveness (Phase 2)Ended earlyNCT01942993
What this trial is testing

The Effects of Treatment With Vemurafenib on the Immune System in Advanced Melanoma

Who this might be right for
Melanoma
Philip Friedlander 3
Not applicableStudy completedNCT01057199
What this trial is testing

Studying Biomarkers in Cell Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Children's Oncology Group 6
Testing effectiveness (Phase 2)Temporarily pausedNCT06630221
What this trial is testing

Eltrombopag as a Novel Therapeutic Approach for Low-risk MDS and CMML With TET2 Mutations

Who this might be right for
Myelodysplastic SyndromesChronic Myelomonocytic Leukemia
Abhay Singh, MD MPH 25
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