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Results for “Genetics of Drug Metabolism”

236 trials

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Showing 20 of 236 results

Testing effectiveness (Phase 2)Study completedNCT02595983
What this trial is testing

The Study of an Investigational Drug, Revusiran (ALN-TTRSC), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Whose Disease Has Continued to Worsen Following Liver Transplant

Who this might be right for
Transthyretin (TTR)-Mediated AmyloidosisFamilial Amyloidotic Polyneuropathy (FAP)ATTR Amyloidosis+1 more
Alnylam Pharmaceuticals 12
Post-approval studies (Phase 4)Study completedNCT00245986
What this trial is testing

Effect of Genetics on Metabolism of Efavirenz

Who this might be right for
Metabolism
National Institutes of Health Clinical Center (CC) 350
Not applicableWithdrawnNCT03041571
What this trial is testing

Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students

Who this might be right for
Narrative MedicineChronic DiseaseTerminal Illness+6 more
University of Florida
Not applicableLooking for participantsNCT07654179
What this trial is testing

Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation

Who this might be right for
DepressionDepressive DisorderOverweight or Obesity+1 more
Riphah International University 200
Not applicableLooking for participantsNCT04278404
What this trial is testing

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Who this might be right for
Coronavirus Infection (COVID-19)Pulmonary Arterial HypertensionUrinary Tract Infections in Children+22 more
Duke University 5,000
Not applicableApproved For MarketingNCT03895528
What this trial is testing

Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome or Progeroid Laminopathy

Who this might be right for
ProgeriaHGPS
Eiger BioPharmaceuticals
Post-approval studies (Phase 4)Study completedNCT00443092
What this trial is testing

Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
CherryPharm 59
Large-scale testing (Phase 3)Study completedNCT00958438
What this trial is testing

PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2)

Who this might be right for
Gout
Regeneron Pharmaceuticals 248
Early research (Phase 1)Study completedNCT03272425
What this trial is testing

Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.

Who this might be right for
Gout
Ardea Biosciences, Inc. 32
Not applicableStudy completedNCT02961179
What this trial is testing

Dairy Products, Diabetes and Genetics

Who this might be right for
Insulin SensitivityType2 Diabetes
CHU de Quebec-Universite Laval 33
Not applicableStudy completedNCT00076323
What this trial is testing

A Test to Predict the Hemolytic Potential of Drugs in G6PD Deficiency

Who this might be right for
Glucosephosphate Dehydrogenase DeficiencyFavism
Walter Reed Army Institute of Research (WRAIR) 14
Not applicableLooking for participantsNCT01441089
What this trial is testing

Collection of Blood From Patients With Cancer, Other Tumors, or Tumor Predisposition Syndromes for Genetic Analysis

Who this might be right for
Prostate CancerBreast CancerLung Cancer+2 more
National Cancer Institute (NCI) 1,100
Post-approval studies (Phase 4)Study completedNCT00782548
What this trial is testing

Comparative Study to Evaluate KADIAN and Avinza in Healthy Adults

Who this might be right for
Healthy
Actavis Inc. 40
Not applicableStudy completedNCT02428660
What this trial is testing

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Who this might be right for
Cytochrome P450 CYP2D6 Enzyme DeficiencyPoor Metabolizer Due to Cytochrome P450 CYP2D6 VariantUltrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant+6 more
Genelex Corporation 341
Testing effectiveness (Phase 2)Study completedNCT02252835
What this trial is testing

Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gout

Who this might be right for
GoutHyperuricemia
Gilead Sciences 32
Not applicableUnknownNCT02964923
What this trial is testing

Genes Polymorphisms and Metabolic Effects of the Second Generation Antipsychotic Drugs in Patients With Schizophrenia

Who this might be right for
Schizophrenia
Xijing Hospital 300
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Not applicableStudy completedNCT00002222
What this trial is testing

Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Hoffmann-La Roche 200
Not applicableUnknownNCT04483661
What this trial is testing

Development of Systems and Precision Medicine - Take Mood Disorder as an Example.

Who this might be right for
Mood Disorders
National Cheng-Kung University Hospital 200
Testing effectiveness (Phase 2)Study completedNCT00174941
What this trial is testing

Long-Term Safety of Febuxostat in Subjects With Gout.

Who this might be right for
Gout
Takeda 116
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