Not applicableStudy completedNCT02113917What this trial is testingChildren and Adult Hemophagocytic Syndrome (HLHa)Who this might be right forHemophagocytic Syndrome Assistance Publique - Hôpitaux de Paris 204
Not applicableUnknownNCT04347460What this trial is testingEstablishing a COVID-19 Prospective Cohort for Identification of Secondary HLHWho this might be right forCOVID Technical University of Munich 20
Not applicableNot Yet RecruitingNCT06491719What this trial is testingA Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCTWho this might be right forCAEBV (Chronic Active Epstein-Barr Virus Infection) SyndromeEBVHemophagocytic Lymphohistiocytoses Beijing Friendship Hospital 15
Not applicableUnknownNCT00006056What this trial is testingPilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic DisordersWho this might be right forChediak-Higashi SyndromeGraft Versus Host DiseaseX-Linked Lymphoproliferative Syndrome+3 more Fairview University Medical Center 40
Not applicableActive Not RecruitingNCT05236764What this trial is testingHaploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 DepletionWho this might be right forAcute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more Baylor College of Medicine 3
Not applicableUnknownNCT04500886What this trial is testingEvaluate the Efficacy and Safety of PEG-rhG-CSF in Patients With Hemophagocytic SyndromeWho this might be right forHemophagocytic Syndrome CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 50
Early research (Phase 1)Active Not RecruitingNCT00710892What this trial is testingCASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide GeneWho this might be right forAcute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more Baylor College of Medicine 10
Not applicableUnknownNCT01095146What this trial is testingNew Candidate Criteria for Diagnosis of Macrophage Activation SyndromeWho this might be right forMacrophage Activation SyndromeLymphohistiocytosis, Hemophagocytic Amrita Institute of Medical Sciences & Research Center 50
Not applicableLooking for participantsNCT06614998What this trial is testingEstablishment of an Early Warning Screening System for Hemophagocytic Lymphohistiocytosis a Multi-center, Prospective StudyWho this might be right forHemophagocytic Syndrome The Affiliated Hospital of Xuzhou Medical University 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367What this trial is testingCD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell TransplantationWho this might be right forBone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more Diane George 37
Early research (Phase 1)Not Yet RecruitingNCT07424222What this trial is testingRuxolitinib for Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (RISE)Who this might be right forImmune Effector Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS) Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 16
Testing effectiveness (Phase 2)WithdrawnNCT02007239What this trial is testingTocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)Who this might be right forHemophagocytic Lymphohistiocytosis Children's Hospital of Philadelphia
Testing effectiveness (Phase 2)Looking for participantsNCT05762640What this trial is testingRuxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH)Who this might be right forHaemophagocytic Lymphohistiocytosis Assistance Publique - Hôpitaux de Paris 20
Not applicableLooking for participantsNCT05146336What this trial is testingCytOSorb TreatMent Of Critically Ill PatientS RegistryWho this might be right forSeptic ShockAcute Respiratory Distress SyndromeTrauma+15 more CytoSorbents, Inc 3,000
Not applicableStudy completedNCT06391814What this trial is testingDonor-Derived EBV-Specific T Cells for Life Threatening EBV-lymphoma (OLIP-EBV-TCL-01-HMR01)Who this might be right forEBV Associated Lymphoma Ciusss de L'Est de l'Île de Montréal 1
Post-approval studies (Phase 4)UnknownNCT05039580What this trial is testingProgrammed Cell Death Protein-1 (PD-1) Monoclonal Antibody for EBV-HLH and CAEBV as First-line TherapyWho this might be right forEBV Infection The First Affiliated Hospital of Soochow University 36
Early research (Phase 1)Active Not RecruitingNCT01494103What this trial is testingAdministration of Donor T Cells With the Caspase-9 Suicide GeneWho this might be right forAcute Lymphoblastic LeukemiaMyelodysplastic SyndromeAcute Myeloid Leukemia+7 more Baylor College of Medicine 15
Testing effectiveness (Phase 2)Looking for participantsNCT01962415What this trial is testingReduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCTWho this might be right forPrimary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more Paul Szabolcs 100
Large-scale testing (Phase 3)Study completedNCT05001737What this trial is testingEvaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLEWho this might be right forMacrophage Activation SyndromeSecondary Hemophagocytic LymphohistiocytosisStill Disease+4 more Swedish Orphan Biovitrum 33
Not applicableLooking for participantsNCT05882175What this trial is testingProspective Validation of the OHI IndexWho this might be right forHLHHemophagocytic LymphohistiocytosesHemophagocytic Syndrome+2 more Meir Medical Center 300