Testing effectiveness (Phase 2)Study completedNCT00867698What this trial is testingAST-120 Used to Treat Mild Hepatic EncephalopathyWho this might be right forMild Hepatic Encephalopathy Ocera Therapeutics 148
Post-approval studies (Phase 4)Looking for participantsNCT04073290What this trial is testingPrevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and LactuloseWho this might be right forHepatic EncephalopathyCirrhosis, LiverPortal Hypertension+2 more Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 238
Testing effectiveness (Phase 2)Study completedNCT02255617What this trial is testingFecal Microbiota Transplantation (FMT) in the Management of Hepatic Encephalopathy (HE): a Pilot StudyWho this might be right forHepatic Encephalopathy University of Alberta 4
Not applicableNot Yet RecruitingNCT07273734What this trial is testingUDCA to Prevent Post-TIPS Hepatic EncephalopathyWho this might be right forHepatic Encephalopathy (HE)TIPS West China Hospital 270
Post-approval studies (Phase 4)Looking for participantsNCT06538077What this trial is testingBCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HEWho this might be right forHepatic EncephalopathyDecompensated CirrhosisMinimal Hepatic Encephalopathy Post Graduate Institute of Medical Education and Research, Chandigarh 336
Not applicableUnknownNCT05466669What this trial is testingPrediction of Post-TIPS Hepatic Encephalopathy in Patients With Liver CirrhosisWho this might be right forHepatic EncephalopathyLiver Cirrhosis Johannes Gutenberg University Mainz 83
Not applicableUnknownNCT05421351What this trial is testingImmune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLFWho this might be right forHepatic EncephalopathyAcute-On-Chronic Liver FailureDecompensated Cirrhosis Post Graduate Institute of Medical Education and Research, Chandigarh 135
Not applicableStudy completedNCT01151475What this trial is testingCerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)Who this might be right forLiver CirrhosisHepatic Encephalopathy University of Aarhus 10
Not applicableWithdrawnNCT01923376What this trial is testingHepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)Who this might be right forHepatic EncephalopathyHECirrhosis+2 more New York Presbyterian Brooklyn Methodist Hospital
Not applicableLooking for participantsNCT07349654What this trial is testingUnderdilated-stent Technique Improves Post-TIPS EncephalopathyWho this might be right forLiver CirrhosisVariceal Bleeding, CirrhosisAscites Hepatic+1 more The Second Affiliated Hospital of Chongqing Medical University 72
Not applicableNot Yet RecruitingNCT07634237What this trial is testingPersonalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic EncephalopathyWho this might be right forCirrhosisRefractory AscitesTIPS Insertion McGill University Health Centre/Research Institute of the McGill University Health Centre 50
Not applicableNot Yet RecruitingNCT07150195What this trial is testingStudy on Proteomic and Microbiome Changes in Patients With Hepatic Encephalopathy (HE)Who this might be right forCirrhoses, LiverHepatic Encephalopathy (HE) The First Affiliated Hospital with Nanjing Medical University 32
Testing effectiveness (Phase 2)Study completedNCT03712280What this trial is testingMNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)Who this might be right forHepatic CirrhosisHepatic Encephalopathy (HE) Mallinckrodt 50
Not applicableStudy completedNCT01283152What this trial is testingEfficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy.Who this might be right forHepatic EncephalopathyCirrhosisPortosystemic Encephalopathy+1 more University of Texas Southwestern Medical Center 50
Testing effectiveness (Phase 2)Study completedNCT01966419What this trial is testingPhase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)Who this might be right forAcute Episode of Overt Hepatic EncephalopathyHepatic Encephalopathy Ocera Therapeutics, Inc. 231
Not applicableStudy completedNCT02377947What this trial is testingA Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]Who this might be right forHepatic Encephalopathy Abbott 50
Testing effectiveness (Phase 2)Study completedNCT00999167What this trial is testingSafety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic EncephalopathyWho this might be right forCirrhosisHepatic Encephalopathy Amgen 189
Early research (Phase 1)Study completedNCT05700695What this trial is testingIntravenous BCAA for HE in ACLF (BCAA-HE-ACLF)Who this might be right forHepatic EncephalopathyAcute-On-Chronic Liver Failure Post Graduate Institute of Medical Education and Research, Chandigarh 114
Not applicableLooking for participantsNCT07046429What this trial is testingAffect of Melatonin on Sleep and Cognition in CirrhosisWho this might be right forHepatic EncephalopathyCovert Hepatic EncephalopathyCirrhosis+1 more Weill Medical College of Cornell University 18
Testing effectiveness (Phase 2)Study completedNCT04899115What this trial is testingVE303 for Treatment of Hepatic Encephalopathy (HE)Who this might be right forCirrhosisHepatic Encephalopathy Patricia Bloom 19