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Results for “Hepatic Impaired”

599 trials

Showing 20 of 599 results

Early research (Phase 1)Study completedNCT04881994
What this trial is testing

Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Who this might be right for
Worsening Chronic Heart FailureDiabetic Nephropathy
Bayer 27
Early research (Phase 1)Study completedNCT05409911
What this trial is testing

Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

Who this might be right for
Hepatic Impairment
Shionogi 25
Early research (Phase 1)Study completedNCT06719128
What this trial is testing

Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants

Who this might be right for
Hepatic InsufficiencyHealthy
Eli Lilly and Company 46
Early research (Phase 1)Study completedNCT04293029
What this trial is testing

Pharmacokinetics and Safety of SHR0302 in Patients With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT04819464
What this trial is testing

Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod

Who this might be right for
HealthyHepatic Impairment
Viatris Innovation GmbH 24
Early research (Phase 1)Study completedNCT00781430
What this trial is testing

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Who this might be right for
Hepatic Insufficiency
Puma Biotechnology, Inc. 27
Early research (Phase 1)Study completedNCT04755075
What this trial is testing

Surufatinib Hepatic Impairment Study

Who this might be right for
Hepatic Impairment
Hutchison Medipharma Limited 16
Early research (Phase 1)Study completedNCT03376841
What this trial is testing

Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites

Who this might be right for
Hepatic Impairment
Allergan 16
Early research (Phase 1)Study completedNCT00416702
What this trial is testing

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic Insufficiency
Novartis 32
Early research (Phase 1)Study completedNCT03369002
What this trial is testing

Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Seladelpar in Subjects With Hepatic Impairment and Healthy Subjects

Who this might be right for
Hepatic Impairment
Gilead Sciences 32
Early research (Phase 1)Study completedNCT04960124
What this trial is testing

Evaluate the Effect of Hepatic Impairment on JNJ-42847922 in Adult Participants

Who this might be right for
HealthyHepatic Impairment
Janssen Research & Development, LLC 24
Early research (Phase 1)Study completedNCT02183376
What this trial is testing

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 33
Early research (Phase 1)Study completedNCT04752540
What this trial is testing

A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Hepatic Impairment

Who this might be right for
Hepatic Impairment
F2G Biotech GmbH 32
Early research (Phase 1)Looking for participantsNCT07250633
What this trial is testing

Pharmacokinetic Study of Vorasidenib in Severe Hepatically Impaired and Matched-Control Participants

Who this might be right for
Severe Hepatic ImpairmentNormal Hepatic Function
Institut de Recherches Internationales Servier (I.R.I.S.) 20
Early research (Phase 1)Study completedNCT03289234
What this trial is testing

Pharmacokinetics Study of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy
Shionogi 22
Early research (Phase 1)Study completedNCT01732263
What this trial is testing

Study of SSP-004184 (SPD602) in Healthy Adults and Subjects With Impaired Liver Function

Who this might be right for
Hepatic ImpairmentHealthy
Shire 44
Early research (Phase 1)Looking for participantsNCT06997276
What this trial is testing

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

Who this might be right for
HealthyHepatic Impairment
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany 32
Early research (Phase 1)Study completedNCT00621725
What this trial is testing

Phase 1 PK Study of Cediranib in Single and Multiple Doses in Hepatically Impaired Patients With Solid Tumours

Who this might be right for
Advanced CancerHepatic Impairment
AstraZeneca 36
Early research (Phase 1)Study completedNCT04546789
What this trial is testing

Effect of Hepatic Impairment on M2951 (BTK Inhibitor) PK

Who this might be right for
Hepatic Impairment
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 24
Early research (Phase 1)Study completedNCT02621047
What this trial is testing

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Who this might be right for
Hepatic Impairment
Hoffmann-La Roche 28
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