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Results for “Hepatic Impairment”

598 trials

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Showing 20 of 598 results

Early research (Phase 1)Study completedNCT03309202
What this trial is testing

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Who this might be right for
Hepatic Impairment
Pfizer 24
Early research (Phase 1)Study completedNCT03562117
What this trial is testing

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Who this might be right for
Infections, Bacterial
GlaxoSmithKline 25
Early research (Phase 1)Study completedNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 69
Early research (Phase 1)UnknownNCT05747664
What this trial is testing

To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function

Who this might be right for
Diabetes Mellitus, Type 2
Daewoong Pharmaceutical Co. LTD. 24
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT03890809
What this trial is testing

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Who this might be right for
Liver DysfunctionHealthy Volunteers
Bristol-Myers Squibb 32
Early research (Phase 1)Study completedNCT01949545
What this trial is testing

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Solid TumorsHematologic MalignanciesHepatic Impairment
Amgen 46
Large-scale testing (Phase 3)UnknownNCT05595109
What this trial is testing

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Who this might be right for
Breast CancerPeripheral NeuropathyCardiac Toxicities+2 more
Tanta University 56
Early research (Phase 1)Study completedNCT03713242
What this trial is testing

Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
Idorsia Pharmaceuticals Ltd. 32
Early research (Phase 1)Looking for participantsNCT07023354
What this trial is testing

Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
HealthyHepatic Impairment
Boehringer Ingelheim 32
Early research (Phase 1)Not Yet RecruitingNCT07457190
What this trial is testing

Pharmacokinetic Study of Buagafuran Capsules in Participants With Hepatic Impairment and Normal Hepatic Function

Who this might be right for
Generalized Anxiety Disorder
Beijing Union Pharmaceutical Factory Ltd 24
Early research (Phase 1)Study completedNCT03277274
What this trial is testing

Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Takeda 25
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT05560464
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT06425198
What this trial is testing

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Participants
Bristol-Myers Squibb 37
Early research (Phase 1)Study completedNCT01012284
What this trial is testing

TMC207 in Patients With Moderately Impaired Hepatic Function

Who this might be right for
Moderate Hepatic Impairment
Tibotec BVBA 16
Early research (Phase 1)Study completedNCT02318836
What this trial is testing

Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects

Who this might be right for
Liver Failure
USWM, LLC (dba US WorldMeds) 24
Early research (Phase 1)Study completedNCT00736905
What this trial is testing

TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.

Who this might be right for
HIVAIDSHepatic Impairment
Tibotec Pharmaceuticals, Ireland 32
Early research (Phase 1)Study completedNCT06692322
What this trial is testing

Test How Zongertinib is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
Liver DiseasesHealthy
Boehringer Ingelheim 29
Early research (Phase 1)Study completedNCT02161770
What this trial is testing

Study to Assess the Blood Levels and Safety of AZD9291 in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

Who this might be right for
Solid Tumours
AstraZeneca 30
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