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Results for “Hepatic Impairment”

569 trials

Showing 20 of 569 results

Early research (Phase 1)Study completedNCT01949545
What this trial is testing

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Solid TumorsHematologic MalignanciesHepatic Impairment
Amgen 46
Early research (Phase 1)Study completedNCT05961397
What this trial is testing

Phase 1 PK Study to Evaluate the PK of CIN-107 in Subjects With Hepatic Impairment

Who this might be right for
Hypertension
AstraZeneca 20
Not applicableStudy completedNCT00382668
What this trial is testing

Dasatinib to See How Liver Impaired and Healthy Subjects Process and React to the Study Drug

Who this might be right for
Liver Diseases
Bristol-Myers Squibb 40
Early research (Phase 1)Study completedNCT06674915
What this trial is testing

Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HRS-5965 in Subjects With Hepatic Impairment

Who this might be right for
Complement Mediated Primary or Secondary Glomerular Diseases
Chengdu Suncadia Medicine Co., Ltd. 24
Early research (Phase 1)Looking for participantsNCT06740799
What this trial is testing

Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
Daiichi Sankyo 12
Early research (Phase 1)Looking for participantsNCT06961643
What this trial is testing

Investigation of Pharmacokinetics and Safety of HRS-7535 in Subjects With Hepatic Impairment and Normal Hepatic Function

Who this might be right for
Diabetes Mellitus
Shandong Suncadia Medicine Co., Ltd. 24
Early research (Phase 1)Looking for participantsNCT06825559
What this trial is testing

Evaluate PK & Safety of Saroglitazar in Subjects With Moderate Hepatic Impairment Due to Cholestatic Liver Disease

Who this might be right for
Cholestatic Liver Disease
Zydus Therapeutics Inc. 6
Early research (Phase 1)Study completedNCT03417778
What this trial is testing

Study to Evaluate the Pharmacokinetics of Filgotinib in Participants With Impaired Hepatic Function

Who this might be right for
Rheumatoid Arthritis
Gilead Sciences 20
Early research (Phase 1)Study completedNCT02170220
What this trial is testing

Pharmacokinetics, Safety and Tolerability of Vortioxetine in Normal Hepatic Function or Severe Hepatic Impairment

Who this might be right for
Severe Hepatic Impairment
Takeda 12
Early research (Phase 1)Study completedNCT02857868
What this trial is testing

A Trial to Evaluate the Pharmacokinetics of ABL001 in Healthy and Hepatic Impaired Subjects

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 32
Early research (Phase 1)Study completedNCT00819468
What this trial is testing

Pharmacokinetics (PK) of 20 mg Teduglutide in Participants With Moderately Impaired Hepatic Function Compared to Healthy Participants

Who this might be right for
Hepatic Impairment
Shire 24
Early research (Phase 1)Study completedNCT05481411
What this trial is testing

Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment

Who this might be right for
Hepatic Impairment
Amgen 25
Early research (Phase 1)WithdrawnNCT05490030
What this trial is testing

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals
Early research (Phase 1)Study completedNCT02191865
What this trial is testing

Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 33
Early research (Phase 1)Study completedNCT03664544
What this trial is testing

PK Study in Subjects With Severe Hepatic Impairment

Who this might be right for
Severe Hepatic ImpairmentHealthy
Tanabe Pharma Corporation 12
Not applicableStudy completedNCT04208165
What this trial is testing

PVB Versus TAP in Hepatic Patients Undergoing Laparoscopic Cholecystectomy

Who this might be right for
Ultrasound TherapyHepatic ImpairmentLaparoscopic Cholecystectomy
Theodor Bilharz Research Institute 60
Early research (Phase 1)Study completedNCT04867941
What this trial is testing

Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196

Who this might be right for
Hepatic Insufficiency
Acerta Pharma BV 18
Early research (Phase 1)UnknownNCT04631575
What this trial is testing

An Investigational Study of SHR6390 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Who this might be right for
Hepatic ImpairmentHealthy Participants
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)UnknownNCT05684653
What this trial is testing

Study to Evaluate Orelabrutinib Tablets in Subjects With Hepatic Impairment and Healthy Subject

Who this might be right for
Hepatic Impairment
Beijing InnoCare Pharma Tech Co., Ltd. 34
Early research (Phase 1)Study completedNCT03521037
What this trial is testing

Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor

Who this might be right for
Neoplasms
pharmaand GmbH 16
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