Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hepatic Impairment”

588 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 588 results

Early research (Phase 1)Study completedNCT05916560
What this trial is testing

LY3437943 in Participants With Impaired and Normal Liver Function

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 43
Early research (Phase 1)Study completedNCT00651027
What this trial is testing

Study To Assess The Impact Of Hepatic Impairment On The Safety, Tolerability And Pharmacokinetics Of Single-Dose 200 Mg Of PF-868554

Who this might be right for
HEPATITIS C (HCV)
Pfizer 24
Not applicableStudy completedNCT01439854
What this trial is testing

Study of Dapagliflozin on Mitochondrial Dysfunction and Impaired Insulin Signaling/Action

Who this might be right for
Insulin SensitivityMultiple Mitochondrial Dysfunctions Syndrome
The University of Texas Health Science Center at San Antonio 18
Early research (Phase 1)Study completedNCT01185873
What this trial is testing

Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 81
Early research (Phase 1)Study completedNCT01565902
What this trial is testing

Pharmacokinetics of BAF312 in Patients With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT02624557
What this trial is testing

Pharmacokinetic Study of Alpelisib in Subjects With Hepatic Impairment.

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 23
Early research (Phase 1)Study completedNCT06093230
What this trial is testing

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Who this might be right for
Subjects With Liver Function InjuryNormal Liver Function Subject
Shanghai Vinnerna Biosciences Co., Ltd. 24
Early research (Phase 1)Study completedNCT05537142
What this trial is testing

Assess the Phamacokinetics of BV100 in Participants with Varying Degrees of Hepatic Impairment

Who this might be right for
Healthy Participants
BioVersys AG 33
Early research (Phase 1)Study completedNCT05098054
What this trial is testing

Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Takeda 36
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Early research (Phase 1)Study completedNCT00432627
What this trial is testing

Impact of Hepatic Impairment on the Pharmacokinetics of Deferasirox.

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 24
Early research (Phase 1)Study completedNCT01600976
What this trial is testing

Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Janssen Infectious Diseases BVBA 24
Early research (Phase 1)Study completedNCT00162097
What this trial is testing

Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic Impairment

Who this might be right for
HIV InfectionsHepatic Impairment
Bristol-Myers Squibb 21
Testing effectiveness (Phase 2)Study completedNCT00867698
What this trial is testing

AST-120 Used to Treat Mild Hepatic Encephalopathy

Who this might be right for
Mild Hepatic Encephalopathy
Ocera Therapeutics 148
Early research (Phase 1)Study completedNCT06813781
What this trial is testing

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004

Who this might be right for
Hepatic Impairment
AstraZeneca 33
Early research (Phase 1)Study completedNCT04694365
What this trial is testing

Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function

Who this might be right for
Hepatic ImpairmentHealthy Subjects
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT06340347
What this trial is testing

Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function

Who this might be right for
Liver Diseases
Pfizer 8
Not applicableStudy completedNCT05960006
What this trial is testing

Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver Cirrhosis

Who this might be right for
Antibiotic ToxicityLiver CirrhosisRenal Insufficiency+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 20
Early research (Phase 1)Ended earlyNCT04322253
What this trial is testing

Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose in Participants With Liver Impairment and Healthy Participants Matched for Age-, Gender-, and Weight

Who this might be right for
Pharmacology, Clinical
Bayer 22
Early research (Phase 1)Study completedNCT01919125
What this trial is testing

Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)

Who this might be right for
Hepatitis C, Chronic
Merck Sharp & Dohme LLC 36
Load More Results