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Results for “Hepatic Impairment”

579 trials

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Showing 20 of 579 results

Not applicableUnknownNCT02893657
What this trial is testing

The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery

Who this might be right for
Cardiac SurgeryHepatic ImpairmentHeart Failure
Semmelweis University Heart and Vascular Center 150
Early research (Phase 1)Not Yet RecruitingNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT02063230
What this trial is testing

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Who this might be right for
Solid Tumors
AstraZeneca 32
Early research (Phase 1)Study completedNCT03521037
What this trial is testing

Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor

Who this might be right for
Neoplasms
pharmaand GmbH 16
Early research (Phase 1)Looking for participantsNCT05484206
What this trial is testing

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Who this might be right for
Hepatic ImpairmentCirrhosis
Vir Biotechnology, Inc. 144
Early research (Phase 1)Study completedNCT02286609
What this trial is testing

A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics

Who this might be right for
Hepatic Impairment
PTC Therapeutics 16
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT06535399
What this trial is testing

Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Celgene 29
Early research (Phase 1)Study completedNCT02004587
What this trial is testing

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Who this might be right for
Hepatic Impairment
LG Life Sciences 28
Early research (Phase 1)Study completedNCT01299454
What this trial is testing

A Study Evaluating the of OPC-34712 in Subjects With Normal Hepatic Function and Hepatically Impaired Subjects

Who this might be right for
Schizophrenia
Otsuka Pharmaceutical Development & Commercialization, Inc. 45
Early research (Phase 1)Study completedNCT01443481
What this trial is testing

Pharmacokinetics (PK) of TKI258 in Cancer Patients With Normal and Impaired Hepatic Function

Who this might be right for
Solid TumorsHepatic Impairment
Novartis Pharmaceuticals 38
Early research (Phase 1)Study completedNCT06485401
What this trial is testing

To Compare the Safety and PK/ PD Characteristics of ADC189 Between Hepatic Impairment and Normal Hepatic Function Subjects

Who this might be right for
Influenza Type AInfluenza Type B
Jiaxing AnDiCon Biotech Co.,Ltd 16
Early research (Phase 1)Study completedNCT06576765
What this trial is testing

Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD0780

Who this might be right for
Hepatic Impairment
AstraZeneca 16
Very early researchStudy completedNCT02998775
What this trial is testing

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Who this might be right for
Hepatic Impairment; Renal Impairment
Eisai Inc. 54
Early research (Phase 1)Study completedNCT00781430
What this trial is testing

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Who this might be right for
Hepatic Insufficiency
Puma Biotechnology, Inc. 27
Not applicableStudy completedNCT03534843
What this trial is testing

A Comparison Between Child-Pugh and Albumin-Bilirubin Scores

Who this might be right for
Rupture, SpontaneousRupture LiverHepatocellular Carcinoma+1 more
Huazhong University of Science and Technology 230
Early research (Phase 1)Study completedNCT02765724
What this trial is testing

Determine Pacritinib Pharmacokinetics in Impaired Hepatic Patients and Healthy Subjects

Who this might be right for
Myelofibrosis
CTI BioPharma 28
Early research (Phase 1)Study completedNCT02101190
What this trial is testing

Pharmacokinetics of BIA 9-1067 in Subjects With Hepatic Impairment

Who this might be right for
Parkinson's Disease
Bial - Portela C S.A. 16
Early research (Phase 1)Study completedNCT02259855
What this trial is testing

Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 36
Large-scale testing (Phase 3)Ended earlyNCT02455167
What this trial is testing

Reversal of Hepatic Impairment in Patients With Hepatitis C Virus (HCV) and Early Decompensation of Cirrhosis

Who this might be right for
Hepatitis C
University of Colorado, Denver 9
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