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Results for “Hepatic Impairment; Renal Impairment”

29 trials

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Showing 20 of 29 results

Early research (Phase 1)Study completedNCT01901133
What this trial is testing

Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group

Who this might be right for
Pharmacokinetics of MDV3100Healthy SubjectsKidney Diseases
Astellas Pharma Europe B.V. 33
Very early researchStudy completedNCT02998775
What this trial is testing

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Who this might be right for
Hepatic Impairment; Renal Impairment
Eisai Inc. 54
Testing effectiveness (Phase 2)Study completedNCT03180619
What this trial is testing

Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Alafenamide (TAF) From Tenofovir Disoproxil Fumarate (TDF) and/or Other Oral Antiviral Treatment (OAV)

Who this might be right for
Chronic Hepatitis B
Gilead Sciences 124
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)UnknownNCT05731804
What this trial is testing

Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir

Who this might be right for
Renal ImpairmentHepatic Impairment
Jiangsu Simcere Pharmaceutical Co., Ltd. 72
Not applicableStudy completedNCT04170309
What this trial is testing

Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases

Who this might be right for
Renal InsufficiencyHepatic InsufficiencyImmunosuppression
Advanz Pharma 428
Large-scale testing (Phase 3)Study completedNCT00604357
What this trial is testing

CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment

Who this might be right for
End Stage Liver DiseaseImpaired Renal Function
University of Regensburg 27
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Not applicableStudy completedNCT05960006
What this trial is testing

Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver Cirrhosis

Who this might be right for
Antibiotic ToxicityLiver CirrhosisRenal Insufficiency+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 20
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT03172884
What this trial is testing

Study of Copanlisib in Hepatic or Renal Impairment

Who this might be right for
Hepatic Insufficiency, Renal Insufficiency
Bayer 30
Testing effectiveness (Phase 2)Ended earlyNCT05900050
What this trial is testing

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®

Who this might be right for
Acute-On-Chronic Liver FailureAscites
Genfit 15
Early research (Phase 1)Study completedNCT06402721
What this trial is testing

Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Who this might be right for
Chronic Kidney DiseaseHepatic Impairment
Bayer 24
Early research (Phase 1)Ended earlyNCT04820621
What this trial is testing

Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment

Who this might be right for
Chronic Kidney Disease
Bayer 5
Not applicableStudy completedNCT03555565
What this trial is testing

Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

Who this might be right for
Type 2 Diabetes Mellitus
Takeda 1,026
Not applicableStudy completedNCT04275375
What this trial is testing

Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.

Who this might be right for
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
National Central University 46
Not applicableStudy completedNCT06600243
What this trial is testing

Influence of Microfiltered-seawater Supplementation and Variable Resistance Training in Blood Pressure, Oxidative Stress, Hepatic, and Renal Biomarkers in Older Women

Who this might be right for
Blood PressureOxidative StressRenal Disease+1 more
University of Valencia 109
Post-approval studies (Phase 4)Not Yet RecruitingNCT07345689
What this trial is testing

The Pharmacokinetics and Safety of Anaprazole Sodium in Special Populations

Who this might be right for
Hepatic InsufficiencyRenal InsufficiencyElderly
Xuanzhu Biopharmaceutical Co., Ltd. 60
Early research (Phase 1)Ended earlyNCT00004239
What this trial is testing

506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
Alliance for Clinical Trials in Oncology 10
Early research (Phase 1)Study completedNCT05112419
What this trial is testing

Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

Who this might be right for
Hepatic ImpairmentRenal Impairment
AstraZeneca 12
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