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Results for “Hepatic Impairment; Renal Impairment”

29 trials

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Showing 20 of 29 results

Very early researchStudy completedNCT02998775
What this trial is testing

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Who this might be right for
Hepatic Impairment; Renal Impairment
Eisai Inc. 54
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Ended earlyNCT00004239
What this trial is testing

506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaLymphoma+2 more
Alliance for Clinical Trials in Oncology 10
Not applicableStudy completedNCT03555565
What this trial is testing

Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

Who this might be right for
Type 2 Diabetes Mellitus
Takeda 1,026
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Not applicableStudy completedNCT02013596
What this trial is testing

Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum

Who this might be right for
Hepatic Dysfunction TransientRenal Function Disorder
Zhihong LU 168
Early research (Phase 1)UnknownNCT05731804
What this trial is testing

Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir

Who this might be right for
Renal ImpairmentHepatic Impairment
Jiangsu Simcere Pharmaceutical Co., Ltd. 72
Testing effectiveness (Phase 2)Ended earlyNCT05900050
What this trial is testing

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®

Who this might be right for
Acute-On-Chronic Liver FailureAscites
Genfit 15
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Not applicableStudy completedNCT06600243
What this trial is testing

Influence of Microfiltered-seawater Supplementation and Variable Resistance Training in Blood Pressure, Oxidative Stress, Hepatic, and Renal Biomarkers in Older Women

Who this might be right for
Blood PressureOxidative StressRenal Disease+1 more
University of Valencia 109
Early research (Phase 1)Study completedNCT01901133
What this trial is testing

Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group

Who this might be right for
Pharmacokinetics of MDV3100Healthy SubjectsKidney Diseases
Astellas Pharma Europe B.V. 33
Early research (Phase 1)Study completedNCT02894385
What this trial is testing

Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201)

Who this might be right for
PharmacokineticsHepatic InsufficiencyRenal Insufficiency
Bayer 29
Early research (Phase 1)Looking for participantsNCT06911320
What this trial is testing

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function

Who this might be right for
Healthy Volunteer StudyHepatic ImpairmentRenal Impairment
Atea Pharmaceuticals, Inc. 28
Early research (Phase 1)Study completedNCT00805090
What this trial is testing

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Who this might be right for
Renal Insufficiency, ChronicHepatic InsufficiencyHealthy
Javelin Pharmaceuticals 37
Early research (Phase 1)Ended earlyNCT04820621
What this trial is testing

Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment

Who this might be right for
Chronic Kidney Disease
Bayer 5
Not applicableStudy completedNCT04170309
What this trial is testing

Collection of Data of Ceftobiprole Treated Patients: Comparison of Patients With and Without Certain Diseases

Who this might be right for
Renal InsufficiencyHepatic InsufficiencyImmunosuppression
Advanz Pharma 428
Early research (Phase 1)Study completedNCT04881994
What this trial is testing

Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Who this might be right for
Worsening Chronic Heart FailureDiabetic Nephropathy
Bayer 27
Early research (Phase 1)Study completedNCT05112419
What this trial is testing

Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

Who this might be right for
Hepatic ImpairmentRenal Impairment
AstraZeneca 12
Early research (Phase 1)Study completedNCT03172884
What this trial is testing

Study of Copanlisib in Hepatic or Renal Impairment

Who this might be right for
Hepatic Insufficiency, Renal Insufficiency
Bayer 30
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