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Results for “Hepatic Impairment; Renal Impairment”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT04881994
What this trial is testing

Learn How Finerenone (BAY94-8862) Moves Into, Through and Out of the Body, How it Affects the Body, and How Safe it is in Adult Participants With Different Degrees of Reduced Liver Function and in Healthy Participants With Similar Age, Weight and Gender Distribution

Who this might be right for
Worsening Chronic Heart FailureDiabetic Nephropathy
Bayer 27
Early research (Phase 1)Study completedNCT06911320
What this trial is testing

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function

Who this might be right for
Healthy Volunteer StudyHepatic ImpairmentRenal Impairment
Atea Pharmaceuticals, Inc. 28
Not applicableStudy completedNCT04275375
What this trial is testing

Autonomic Modulation After Spinal Anesthesia With Depth of Anesthesia and Vital Signs.

Who this might be right for
Participants Scheduled for Surgery Under Spinal Anesthesia Without Impairment of Renal, Hepatic, Cardiac or Respiratory Function
National Central University 46
Early research (Phase 1)Study completedNCT05112419
What this trial is testing

Assess Zibotentan Pharmacokinetics in Participants With Moderate Hepatic and Moderate Renal Impairment

Who this might be right for
Hepatic ImpairmentRenal Impairment
AstraZeneca 12
Early research (Phase 1)Ended earlyNCT04820621
What this trial is testing

Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment

Who this might be right for
Chronic Kidney Disease
Bayer 5
Very early researchStudy completedNCT02998775
What this trial is testing

Phase 0 Study in Healthy, Hepatic and Renal Impaired Subjects to Obtain Plasma for Lenvatinib Protein Binding

Who this might be right for
Hepatic Impairment; Renal Impairment
Eisai Inc. 54
Early research (Phase 1)Study completedNCT06402721
What this trial is testing

Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Who this might be right for
Chronic Kidney DiseaseHepatic Impairment
Bayer 24
Not applicableNot Yet RecruitingNCT07579663
What this trial is testing

Personalized Two-stage Regional Citrate Anticoagulation for CRRT in Patients With Citrate Metabolism Impairment

Who this might be right for
AKI - Acute Kidney InjuryCKD 5D, HemodialysisHepatic Failure
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 142
Early research (Phase 1)Study completedNCT06529796
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of Inaxaplin in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Focal Segmental Glomerulosclerosis (FSGS)
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Looking for participantsNCT07006688
What this trial is testing

An IDH1m Inhibitor in Participants With IDH1-Mutated Malignancies and Hepatic or Renal Impairment

Who this might be right for
IDH1-Mutated Malignancies
Servier Bio-Innovation LLC 30
Early research (Phase 1)Study completedNCT00118170
What this trial is testing

Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function

Who this might be right for
Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid TissueNodal Marginal Zone B-cell LymphomaRecurrent Adult Burkitt Lymphoma+42 more
National Cancer Institute (NCI) 150
Early research (Phase 1)Study completedNCT02696642
What this trial is testing

Phase I Study of Anetumab Ravtansine in Hepatic or Renal Impairment

Who this might be right for
Neoplasms
Bayer 54
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT00805090
What this trial is testing

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Who this might be right for
Renal Insufficiency, ChronicHepatic InsufficiencyHealthy
Javelin Pharmaceuticals 37
Not applicableStudy completedNCT05960006
What this trial is testing

Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver Cirrhosis

Who this might be right for
Antibiotic ToxicityLiver CirrhosisRenal Insufficiency+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 20
Early research (Phase 1)Study completedNCT05624710
What this trial is testing

Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

Who this might be right for
Renal InsufficiencyKidney Diseases
Incyte Corporation 25
Post-approval studies (Phase 4)Not Yet RecruitingNCT07345689
What this trial is testing

The Pharmacokinetics and Safety of Anaprazole Sodium in Special Populations

Who this might be right for
Hepatic InsufficiencyRenal InsufficiencyElderly
Xuanzhu Biopharmaceutical Co., Ltd. 60
Early research (Phase 1)Study completedNCT01901133
What this trial is testing

Hepatic Impairment Study With MDV3100 in Subjects With Mild and Moderate Hepatic Impairment Compared to a Healthy Control Group

Who this might be right for
Pharmacokinetics of MDV3100Healthy SubjectsKidney Diseases
Astellas Pharma Europe B.V. 33
Early research (Phase 1)Study completedNCT03172884
What this trial is testing

Study of Copanlisib in Hepatic or Renal Impairment

Who this might be right for
Hepatic Insufficiency, Renal Insufficiency
Bayer 30
Not applicableStudy completedNCT02013596
What this trial is testing

Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum

Who this might be right for
Hepatic Dysfunction TransientRenal Function Disorder
Zhihong LU 168
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