Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hepatic Impairment (HI)”

15 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 15 of 15 results

Early research (Phase 1)Looking for participantsNCT07422610
What this trial is testing

Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Advanced Malignancies and Hepatic Impairment
Novartis Pharmaceuticals 24
Early research (Phase 1)Looking for participantsNCT06962332
What this trial is testing

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

Who this might be right for
Hepatic ImpairmentModerate Hepatic Impairment
Exelixis 20
Early research (Phase 1)Study completedNCT07324616
What this trial is testing

Evaluate EDG-7500 in Adults With Hepatic Impairment

Who this might be right for
Hepatic Impairment (HI)
Edgewise Therapeutics, Inc. 25
Not applicableStudy completedNCT01054586
What this trial is testing

Fosamprenavir in Pts With Hepatic Impairment

Who this might be right for
Infection, Human Immunodeficiency Virus
GlaxoSmithKline 167
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT04056468
What this trial is testing

Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Millennium Pharmaceuticals, Inc. 24
Early research (Phase 1)Looking for participantsNCT07809802
What this trial is testing

Pharmacokinetic Study of Vorolanib Tablets in Trial Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment (HI)
Betta Pharmaceuticals Co., Ltd. 36
Early research (Phase 1)Study completedNCT05753592
What this trial is testing

Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 38
Early research (Phase 1)Study completedNCT06858696
What this trial is testing

Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function

Who this might be right for
Hepatic Insufficiency
X4 Pharmaceuticals 39
Early research (Phase 1)Looking for participantsNCT07715149
What this trial is testing

A Pharmacokinetic Study of D-2570 in Participants With Hepatic Impairment and Normal Hepatic Function

Who this might be right for
Healthy Adult ParticipantsHepatic Impairment (HI)
InventisBio Co., Ltd 24
Early research (Phase 1)Looking for participantsNCT07682818
What this trial is testing

Pharmacokinetics of Petrelintide in Participants With Impaired Hepatic Function

Who this might be right for
Impaired Hepatic Function
Zealand Pharma 36
Early research (Phase 1)Study completedNCT06841315
What this trial is testing

A Varegacestat Hepatic Impairment Study

Who this might be right for
Healthy VolunteerHepatic Impairment (HI)
Immunome, Inc. 35
Early research (Phase 1)Study completedNCT04950764
What this trial is testing

An Open-Label Study Following Oral Dosing of Seladelpar to Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

Who this might be right for
Primary Biliary CholangitisCompensated CirrhosisHepatic Impairment
Gilead Sciences 24
Early research (Phase 1)Study completedNCT06442436
What this trial is testing

Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Who this might be right for
Hepatic Impairment (HI)
Merck Sharp & Dohme LLC 24
Early research (Phase 1)Ended earlyNCT04252417
What this trial is testing

HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects

Who this might be right for
Healthy VolunteersHepatic Impairment of Moderate Child Pugh Category
MedDay Pharmaceuticals SA 15