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Results for “Hepatic Impairment (HI)”

12 trials

Showing 12 of 12 results

Early research (Phase 1)Study completedNCT04950764
What this trial is testing

An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

Who this might be right for
Primary Biliary CholangitisCompensated CirrhosisHepatic Impairment
Gilead Sciences 24
Early research (Phase 1)Ended earlyNCT04252417
What this trial is testing

HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects

Who this might be right for
Healthy VolunteersHepatic Impairment of Moderate Child Pugh Category
MedDay Pharmaceuticals SA 15
Early research (Phase 1)Looking for participantsNCT07324616
What this trial is testing

Evaluate EDG-7500 in Adults With Hepatic Impairment

Who this might be right for
Hepatic Impairment (HI)
Edgewise Therapeutics, Inc. 32
Early research (Phase 1)Study completedNCT04056468
What this trial is testing

Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Millennium Pharmaceuticals, Inc. 24
Early research (Phase 1)Looking for participantsNCT06962332
What this trial is testing

Pharmacokinetics (PK) and Safety of Zanzalintinib in Participants With Moderate Hepatic Impairment (HI)

Who this might be right for
Hepatic ImpairmentModerate Hepatic Impairment
Exelixis 20
Early research (Phase 1)Study completedNCT05753592
What this trial is testing

Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 38
Early research (Phase 1)Looking for participantsNCT06858696
What this trial is testing

Investigate Pharmacokinetics (PK) and Safety of a Single Dose of Mavorixafor in Participants With Hepatic Impairment (HI) Compared to Matched Healthy Volunteers With Normal Hepatic Function

Who this might be right for
Hepatic Insufficiency
X4 Pharmaceuticals 48
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT06841315
What this trial is testing

A Varegacestat Hepatic Impairment Study

Who this might be right for
Healthy VolunteerHepatic Impairment (HI)
Immunome, Inc. 35
Not applicableStudy completedNCT01054586
What this trial is testing

Fosamprenavir in Pts With Hepatic Impairment

Who this might be right for
Infection, Human Immunodeficiency Virus
GlaxoSmithKline 167
Early research (Phase 1)Not Yet RecruitingNCT07422610
What this trial is testing

Pharmacokinetics and Safety Study of Pelabresib in Patients With Advanced Malignancies and Hepatic Impairment

Who this might be right for
Advanced Malignancies and Hepatic Impairment
Novartis Pharmaceuticals 24
Early research (Phase 1)Looking for participantsNCT06442436
What this trial is testing

Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Who this might be right for
Hepatic Impairment (HI)
Merck Sharp & Dohme LLC 32

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