Large-scale testing (Phase 3)Study completedNCT00125151What this trial is testingC1-Esteraseremmer-N for the Treatment of Hereditary (and Acquired) AngioedemaWho this might be right forAngioedema Prothya Biosolutions 15
Testing effectiveness (Phase 2)Ended earlyNCT05055258What this trial is testingA Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or IIWho this might be right forAngioedema, Hereditary, Types I and II KalVista Pharmaceuticals, Ltd. 33
Not applicableApproved For MarketingNCT06628713What this trial is testingTreatment of Angioedema Attacks in Adolescent and Adult Patients 12 Years and Older With HAE Type I or II With SebetralstatWho this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd.
Testing effectiveness (Phase 2)Study completedNCT01576523What this trial is testingEvaluate the Clinical Pharmacology and Safety of C1-esterase Inhibitor Administered by the Subcutaneous RouteWho this might be right forHereditary Angioedema Types I and II CSL Behring 18
Not applicableStudy completedNCT07009262What this trial is testingA Study Observing US Patients With HAE Type I or II Who Take Icatibant to Treat HAE AttacksWho this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd. 88
Not applicableNot Yet RecruitingNCT07218393What this trial is testingA Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in EgyptWho this might be right forHereditary Angioedema (HAE) Takeda 100
Testing effectiveness (Phase 2)WithdrawnNCT01832896What this trial is testingStudy to Assess the Tolerability and Safety of Ecallantide in Children and Adolescents With Hereditary AngioedemaWho this might be right forHereditary Angioedema Types I and II NYU Langone Health
Early research (Phase 1)Study completedNCT01760343What this trial is testingEvaluate the Safety and Pharmacokinetics of Two Formulations of C1-esterase InhibitorWho this might be right forHereditary Angioedema Types I and II CSL Behring 16
Large-scale testing (Phase 3)Active Not RecruitingNCT05505916What this trial is testingAn Open-label Extension Trial to Evaluate the Long-term Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)Who this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd. 145
Not applicableStudy completedNCT03029728What this trial is testingBiomarker for Hereditary AngioEdema DiseaseWho this might be right forC1 Esterase Inhibitor DeficiencyAngio EdemaC4 Deficiency+5 more CENTOGENE GmbH Rostock 42
Not applicableEnded earlyNCT04091113What this trial is testingHereditary Angioedema Kininogen AssayWho this might be right forHereditary Angioedema CENTOGENE GmbH Rostock 59
Not applicableStudy completedNCT03558009What this trial is testingEpidemiological Analysis for Hereditary Angioedema DiseaseWho this might be right forAbdominal PainFunctional Abdominal Pain CENTOGENE GmbH Rostock 2,318
Large-scale testing (Phase 3)Study completedNCT02316353What this trial is testingEvaluate the Long-term Clinical Safety and Efficacy of Subcutaneously Administered C1-esterase Inhibitor in the Prevention of Hereditary AngioedemaWho this might be right forHereditary Angioedema Types I and II CSL Behring 126
Large-scale testing (Phase 3)Study completedNCT06467084What this trial is testingOpen-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or IIWho this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd. 36
Large-scale testing (Phase 3)Study completedNCT00997204What this trial is testingEASSI - Evaluation of the Safety of Self-Administration With IcatibantWho this might be right forHereditary Angioedema Shire 151
Large-scale testing (Phase 3)Study completedNCT05259917What this trial is testingA Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)Who this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd. 136
Testing effectiveness (Phase 2)Study completedNCT04208412What this trial is testingA Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or IIWho this might be right forHereditary Angioedema KalVista Pharmaceuticals, Ltd. 84
Large-scale testing (Phase 3)Study completedNCT02741596What this trial is testingLong-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAEWho this might be right forHereditary Angioedema (HAE) Shire 212
Large-scale testing (Phase 3)Study completedNCT02586805What this trial is testingEfficacy and Safety Study of DX-2930 to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAEWho this might be right forHereditary Angioedema (HAE) Shire 125
Not applicableActive Not RecruitingNCT05469789What this trial is testingLanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE)Who this might be right forHereditary Angioedema (HAE) Takeda 50