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Results for “Hereditary Optic Neuropathies”

138 trials

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Showing 20 of 138 results

Very early researchStudy completedNCT00825591
What this trial is testing

Biological Clock Dysfunction in Optic Nerve Hypoplasia

Who this might be right for
Biological Clock DysfunctionOptic Nerve Hypoplasia
Yale University 100
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT05676034
What this trial is testing

AMX0035 in Adult Patients With Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Amylyx Pharmaceuticals Inc. 12
Testing effectiveness (Phase 2)UnknownNCT05659368
What this trial is testing

Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1

Who this might be right for
Wolfram Syndrome
Ospedale San Raffaele 10
Large-scale testing (Phase 3)UnknownNCT01316744
What this trial is testing

Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain

Who this might be right for
Cancer
University of Glasgow 214
Testing effectiveness (Phase 2)UnknownNCT04940572
What this trial is testing

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Centre d'Etude des Cellules Souches 23
Large-scale testing (Phase 3)UnknownNCT05660447
What this trial is testing

A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR

Who this might be right for
Rhegmatogenous Retinal DetachmentProliferative Vitreoretinopathy
Wills Eye 80
Not applicableStudy completedNCT05555784
What this trial is testing

Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Argo Sante 12
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Not applicableEnded earlyNCT02982499
What this trial is testing

Biomechanics of Optic Neuropathy

Who this might be right for
Optic Neuropathy
University of Miami 10
Not applicableStudy completedNCT01421381
What this trial is testing

RHODOS Follow-up Single-visit Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 60
Early research (Phase 1)Study completedNCT00003597
What this trial is testing

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

Who this might be right for
Cancer
Children's Oncology Group 16
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Study completedNCT02839720
What this trial is testing

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis Type 1Optic Nerve Glioma
National Cancer Institute (NCI) 11
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableStudy completedNCT04723160
What this trial is testing

Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph

Who this might be right for
Diabetic RetinopathyRetinal Vein OcclusionRetinal Artery Occlusion+10 more
Visionary Intelligence Ltd. 748
Not applicableStudy completedNCT01267422
What this trial is testing

Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber Hereditary Optic Neuropathy
Bin Li 9
Early research (Phase 1)Study completedNCT00019630
What this trial is testing

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Soft Tissue SarcomaChildhood Liver CancerBone Cancer+2 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT04580979
What this trial is testing

Natural History Study of FDXR Mutation-related Mitochondriopathy

Who this might be right for
Neurodegenerative Disease, HereditaryMitochondrial DiseasesOptic Atrophy
State University of New York at Buffalo 33
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