Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Hereditary Optic Neuropathies”

134 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 134 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05660447
What this trial is testing

A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR

Who this might be right for
Rhegmatogenous Retinal DetachmentProliferative Vitreoretinopathy
Wills Eye 80
Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Post-approval studies (Phase 4)Not Yet RecruitingNCT07240649
What this trial is testing

Outcomes From Hyperbaric Oxygen (HBO2) Treatment for Emerging Indications

Who this might be right for
Post-COVID-19 ConditionUlcerative ColitisCrohn Disease+38 more
Jay C. Buckey Jr. 100
Testing effectiveness (Phase 2)Study completedNCT02839720
What this trial is testing

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis Type 1Optic Nerve Glioma
National Cancer Institute (NCI) 11
Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Large-scale testing (Phase 3)Study completedNCT03746522
What this trial is testing

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Who this might be right for
Bardet Biedl Syndrome (BBS)Alström Syndrome (AS)
Rhythm Pharmaceuticals, Inc. 52
Early research (Phase 1)Study completedNCT00101270
What this trial is testing

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Diffuse Large Cell Lymphoma+26 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00006102
What this trial is testing

Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Brain and Central Nervous System TumorsLymphomaNeuroblastoma+3 more
National Cancer Institute (NCI) 200
Not applicableLooking for participantsNCT00874783
What this trial is testing

Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases

Who this might be right for
Neurodegenerative Disorders
Hadassah Medical Organization 120
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Not applicableLooking for participantsNCT03988764
What this trial is testing

Monogenic Diabetes Misdiagnosed as Type 1

Who this might be right for
Diabetes Mellitus, Type 1Monogenic DiabetesNeonatal Diabetes+4 more
McGill University Health Centre/Research Institute of the McGill University Health Centre 5,000
Early research (Phase 1)Study completedNCT00056199
What this trial is testing

EYE001 to Treat Retinal Tumors in Patients With Von Hippel-Lindau Syndrome

Who this might be right for
Hippel-Lindau Disease
National Eye Institute (NEI) 5
Testing effectiveness (Phase 2)Looking for participantsNCT05733572
What this trial is testing

Safety and Efficacy of the PAINLESS Nerve Growth Factor CHF6467 in Optic Pathway Glioma (OPG)

Who this might be right for
Optic Pathway Glioma
Benedetto Falsini 36
Early research (Phase 1)Not Yet RecruitingNCT07258667
What this trial is testing

Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)Leber's Hereditary Optic Neuropathy (LHON)Mitochondrial Disease+1 more
University Hospital, Angers 13
Not applicableStudy completedNCT00804102
What this trial is testing

Transcorneal Electrical Stimulation Therapy for Retinal Disease

Who this might be right for
Retinitis PigmentosaMacula OffPrimary Open Angle Glaucoma+8 more
Okuvision GmbH 80
Testing effectiveness (Phase 2)UnknownNCT04940572
What this trial is testing

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Who this might be right for
Wolfram Syndrome
Centre d'Etude des Cellules Souches 23
Not applicableStudy completedNCT01892943
What this trial is testing

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 306
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Large-scale testing (Phase 3)Ended earlyNCT01132547
What this trial is testing

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Who this might be right for
Cancer
University of South Florida 22
Load More Results