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Results for “Hereditary Optic Neuropathies”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT00030108
What this trial is testing

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+7 more
National Institutes of Health Clinical Center (CC) 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07750678
What this trial is testing

Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal Dystrophy

Who this might be right for
Hereditary Corneal DystrophyCorneal AbnormalityCorneal Dystrophies+1 more
GenEditBio Limited 30
Not applicableStudy completedNCT02455414
What this trial is testing

Tracking Neurodegeneration in Early Wolfram Syndrome

Who this might be right for
Type 1 DiabetesDiabetes InsipidusDiabetes Mellitus+1 more
Washington University School of Medicine 101
Not applicableUnknownNCT03760055
What this trial is testing

Assessment of Visual Function With a Portable Brain-computer Interface

Who this might be right for
GlaucomaAge Related Macular DegenerationOptic Neuropathy+1 more
NGoggle 200
Early research (Phase 1)Study completedNCT00053118
What this trial is testing

Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer

Who this might be right for
Brain and Central Nervous System TumorsLymphomaNeuroblastoma+1 more
Roswell Park Cancer Institute 1
Not applicableStudy completedNCT00665795
What this trial is testing

Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy

Who this might be right for
Dysthyroid Orbitopathy
University of Sao Paulo 80
Early research (Phase 1)Study completedNCT02415153
What this trial is testing

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Who this might be right for
Neurofibromatosis Type 1Recurrent Childhood Brain Stem GliomaRecurrent Childhood Visual Pathway Glioma+2 more
National Cancer Institute (NCI) 29
Not applicableNot Yet RecruitingNCT07075887
What this trial is testing

Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

Who this might be right for
Neuro-OphthalmologyOptic NeuropathiesOptic Atrophy, Hereditary, Leber+3 more
Barboni 70
Not applicableLooking for participantsNCT06682819
What this trial is testing

Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)

Who this might be right for
Healthy SubjectsLeber Hereditary Optic Neuropathy
Hôpital Necker-Enfants Malades 90
Testing effectiveness (Phase 2)Looking for participantsNCT06970106
What this trial is testing

Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy (Myrtle)

Who this might be right for
OPA1 Gene MutationAutosomal Dominant Optic AtrophyHereditary Optic Atrophies+1 more
PYC Therapeutics 24
Testing effectiveness (Phase 2)Study completedNCT02693119
What this trial is testing

A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide Topical Ophthalmic Solution for Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Stealth BioTherapeutics Inc. 12
Testing effectiveness (Phase 2)Looking for participantsNCT07303296
What this trial is testing

Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients

Who this might be right for
Leber Hereditary Optic Disease
GenSight Biologics 14
Large-scale testing (Phase 3)Study completedNCT03746522
What this trial is testing

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Who this might be right for
Bardet Biedl Syndrome (BBS)Alström Syndrome (AS)
Rhythm Pharmaceuticals, Inc. 52
Large-scale testing (Phase 3)Looking for participantsNCT06760546
What this trial is testing

A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

Who this might be right for
Hypothalamic ObesityMultiple Pituitary Hormone Deficiency Genetic FormSepto-Optic Dysplasia+3 more
Rhythm Pharmaceuticals, Inc. 39
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableUnknownNCT05353413
What this trial is testing

Diffusion Weighted Magnetic Resonance Imaging and the Optic Nerve Neuropathy.

Who this might be right for
Ischemic Optic NeuropathyOptic NeuritisCompressive Optic Neuropathy+3 more
Medical University of Bialystok 20
Not applicableStudy completedNCT01892943
What this trial is testing

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 306
Very early researchLooking for participantsNCT04561557
What this trial is testing

Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System

Who this might be right for
Autoimmune DiseasesAutoimmune Diseases of the Nervous SystemNeuromyelitis Optica Spectrum Disorder+7 more
Tongji Hospital 36
Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
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