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Results for “High Risk MDS”

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Showing 20 of 0 results

Not applicableLooking for participantsNCT07183878
What this trial is testing

Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study)

Who this might be right for
Acute Myeloid LeukemiaHigh-Risk Acute Myeloid LeukemiaMyelodysplastic Syndromes+1 more
First Affiliated Hospital of Zhejiang University 138
Testing effectiveness (Phase 2)Looking for participantsNCT03214562
What this trial is testing

Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
High Risk Myelodysplastic SyndromeRecurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
M.D. Anderson Cancer Center 116
Testing effectiveness (Phase 2)UnknownNCT00838240
What this trial is testing

Clofarabine, Cytarabine, and Idarubicin in Treating Patients With Intermediate-Risk or High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplasia

Who this might be right for
LeukemiaMyelodysplastic Syndromes
European Organisation for Research and Treatment of Cancer - EORTC 114
Testing effectiveness (Phase 2)Study completedNCT00143559
What this trial is testing

Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

Who this might be right for
LeukemiaAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+6 more
St. Jude Children's Research Hospital 17
Early research (Phase 1)Ended earlyNCT04477291
What this trial is testing

CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Aptose Biosciences Inc. 45
Early research (Phase 1)Looking for participantsNCT03326310
What this trial is testing

Selumetinib and Azacitidine in High Risk Chronic Blood Cancers

Who this might be right for
Chronic Myeloid LeukemiaMyelofibroses
University of Chicago 18
Large-scale testing (Phase 3)Study completedNCT00454480
What this trial is testing

Combination Chemotherapy With or Without Gemtuzumab Ozogamicin or Tipifarnib in Treating Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
LeukemiaMyelodysplastic Syndromes
The University of New South Wales 2,000
Not applicableStudy completedNCT05125341
What this trial is testing

Natural History Study of Adult Patients With Paroxysmal Nocturnal Hemoglobinuria of High-risk Hemolysis in China

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria, Natural History Study
CARE Pharma Shanghai Ltd. 67
Early research (Phase 1)Ended earlyNCT05275439
What this trial is testing

Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Shattuck Labs, Inc. 106
Early research (Phase 1)Ended earlyNCT00049582
What this trial is testing

Decitabine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)+10 more
National Cancer Institute (NCI) 36
Large-scale testing (Phase 3)Study completedNCT00008359
What this trial is testing

Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment

Who this might be right for
Cancer
Memorial Sloan Kettering Cancer Center
Testing effectiveness (Phase 2)Study completedNCT02775903
What this trial is testing

An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
Celgene 213
Testing effectiveness (Phase 2)Looking for participantsNCT07155226
What this trial is testing

Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression

Who this might be right for
Acute Lymphoblastic LeukaemiaAcute Myeloid LeukaemiaHigher-risk Myelodysplastic Syndromes
AstraZeneca 84
Testing effectiveness (Phase 2)Looking for participantsNCT07532824
What this trial is testing

Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)/AMLProton Therapy+2 more
Institute of Hematology and Blood Transfusion, Czech Republic 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07153497
What this trial is testing

Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
National Cancer Institute (NCI) 132
Testing effectiveness (Phase 2)Looking for participantsNCT07301866
What this trial is testing

A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.

Who this might be right for
Acute Leukemia, High RiskMyelodysplastic Syndromes, High RiskHematologic Malignancy Requiring an Allogeneic Hematopoietic Stem Cell Transplant Lacking a Donor
Ciusss de L'Est de l'Île de Montréal 7
Testing effectiveness (Phase 2)Ended earlyNCT00963872
What this trial is testing

Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer

Who this might be right for
LeukemiaLymphomaMultiple Myeloma+1 more
Masonic Cancer Center, University of Minnesota 31
Early research (Phase 1)Looking for participantsNCT06297941
What this trial is testing

Study of REM-422 in Patients With AML or Higher Risk MDS

Who this might be right for
Myelodysplastic SyndromesHigher Risk Myelodysplastic SyndromesAcute Myeloid Leukemia+1 more
Remix Therapeutics 100
Large-scale testing (Phase 3)Looking for participantsNCT04184505
What this trial is testing

Feasibility of Allogeneic Stem Cell Transplantation in Higher-risk-MDS (ACROBAT)

Who this might be right for
High-risk MDS
Gruppo Italiano Malattie EMatologiche dell'Adulto 274
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
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