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Results for “High-risk Muscle Invasive Urothelial Carcinoma”

45 trials

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Showing 20 of 45 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07808216
What this trial is testing

Toripalimab Combined With Intravesical Gemcitabine as Adjuvant Therapy for High-Risk Non-Muscle-Invasive Bladder Cancer After TURBT

Who this might be right for
Non Muscle Invasive Bladder Cancer
Tianjin First Central Hospital 54
Not applicableWithdrawnNCT03238664
What this trial is testing

Robot-Assisted Laparoscopic High-Intensity Focused Ultrasound and Radical Cystectomy for Thermal Ablation of Muscle Invasive Cells in Patients With Bladder Tumors

Who this might be right for
Infiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaTransitional Cell Carcinoma
University of Southern California
Testing effectiveness (Phase 2)Study completedNCT04496219
What this trial is testing

Acupuncture for the Treatment of Intravesical BCG-Related Adverse Events in High-Risk Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder Urothelial Carcinoma In SituRecurrent Bladder Urothelial CarcinomaStage 0a Bladder Cancer AJCC v8+3 more
Fred Hutchinson Cancer Center 45
Early research (Phase 1)Study completedNCT02808143
What this trial is testing

Pembrolizumab and BCG Solution in Treating Patients With Recurrent Non-Muscle-Invasive Bladder Cancer

Who this might be right for
Recurrent Bladder CarcinomaStage 0a Bladder Urothelial CarcinomaStage 0is Bladder Urothelial Carcinoma+1 more
Northwestern University 9
Large-scale testing (Phase 3)Looking for participantsNCT07720284
What this trial is testing

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

Who this might be right for
High-risk Muscle Invasive Urothelial Carcinoma
AstraZeneca 915
Testing effectiveness (Phase 2)UnknownNCT04730232
What this trial is testing

Tilelizumab Combined With Nab-Paclitaxel for High-Risk Non-Muscle-Invasive Urothelial Bladder Carcinoma Which is Not Completely Resectable

Who this might be right for
High-RiskNon-Muscle Invasive Bladder Urothelial Carcinoma
Tianjin Medical University Second Hospital 63
Large-scale testing (Phase 3)Active Not RecruitingNCT06462001
What this trial is testing

BCG + MMC: Adding Mitomycin C to BCG in High-risk, Non-muscle-invasive Bladder Cancer

Who this might be right for
Transitional Cell CarcinomaTransurethral Resection
Nottingham University Hospitals NHS Trust 500
Large-scale testing (Phase 3)Looking for participantsNCT06493552
What this trial is testing

Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors

Who this might be right for
Muscle-Invasive Bladder CarcinomaMetastatic Urothelial Carcinoma
Vasgene Therapeutics, Inc 700
Large-scale testing (Phase 3)Looking for participantsNCT07480356
What this trial is testing

Efficacy and Safety of Intravesical TARA-002 Compared With Investigator's Choice of Intravesical Chemotherapy in Participants With BCG-naïve High-grade Non-muscle Invasive Bladder Cancer

Who this might be right for
Bladder (Urothelial, Transitional Cell) CancerNon-Muscle Invasive Bladder CarcinomaNon-muscle Invasive Bladder Cancer With Carcinoma in Situ
Protara Therapeutics 284
Testing effectiveness (Phase 2)Study completedNCT03636256
What this trial is testing

Evaluation of NanoDoce® in Participants With Urothelial Carcinoma

Who this might be right for
Bladder CancerUrothelial CarcinomaUrinary Bladder Neoplasm+6 more
NanOlogy, LLC 36
Testing effectiveness (Phase 2)Study completedNCT04311580
What this trial is testing

Intravesical Electromotive Mitomycin After Bacillus Calmette-Guérin Failure

Who this might be right for
Bladder Cancer
University of Rome Tor Vergata 52
Large-scale testing (Phase 3)Ended earlyNCT02450331
What this trial is testing

Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection

Who this might be right for
Carcinoma, Transitional Cell
Hoffmann-La Roche 809
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07064863
What this trial is testing

A Tumor Immune Biomarker Guided Approach for Improving Response to BCG in Patients With High-risk NMIBC.

Who this might be right for
NMIBCNon-Muscle Invasive Bladder Urothelial CarcinomaBladder (Urothelial, Transitional Cell) Cancer+1 more
Queen's University 31
Testing effectiveness (Phase 2)Study completedNCT01939756
What this trial is testing

Intravesical Natural Baobab Oil in the Management of BCG-induced Lower Urinary Tract Symptoms

Who this might be right for
Superficial Bladder CancerLower Urinary Tract Symptoms
Savino M. Di Stasi 50
Early research (Phase 1)Study completedNCT03053635
What this trial is testing

Intravesical Photodynamic Therapy (PDT) in BCG Refractory High-Risk Non-muscle Invasive Bladder Cancer (NMIBC) Patients

Who this might be right for
Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCG
Theralase® Technologies Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT07322263
What this trial is testing

Intravesical GEM/DOCE for HR BCG-Unresponsive NMIBC

Who this might be right for
Bladder CancerNon-Muscle Invasive Bladder Cancer (NMIBC)Urothelial Carcinoma+8 more
Michael A. O'Donnell 174
Testing effectiveness (Phase 2)Active Not RecruitingNCT03504163
What this trial is testing

Pembrolizumab (MK-3475) and Bacillus Calmette-Guérin (BCG) as First-Line Treatment for High-Risk T1 Non-Muscle-Invasive Bladder Cancer (NMIBC) and High-Grade Non-Muscle-Invasive Upper Tract Urothelial Carcinoma (NMI-UTUC)]

Who this might be right for
Bladder Cancer
Memorial Sloan Kettering Cancer Center 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT03317158
What this trial is testing

Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

Who this might be right for
Urothelial CarcinomaBladder Cancer
Noah Hahn, M.D. 186
Not applicableLooking for participantsNCT06991868
What this trial is testing

Prospective Cohort Study on Monitoring Recurrence of Urothelial Carcinoma Based on Detection of Urinary Microscopic Residual Disease (MRD)

Who this might be right for
NMIBCMIBCUTUC
Peking University First Hospital 300
Very early researchActive Not RecruitingNCT02812420
What this trial is testing

Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery

Who this might be right for
HydronephrosisInfiltrating Bladder Urothelial Carcinoma Sarcomatoid VariantInfiltrating Bladder Urothelial Carcinoma, Micropapillary Variant+16 more
M.D. Anderson Cancer Center 54
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