Large-scale testing (Phase 3)UnknownNCT02912702What this trial is testingL-DEP as an Initial Treatment for EBV-HLHWho this might be right forHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 120
Large-scale testing (Phase 3)Looking for participantsNCT02670707What this trial is testingVinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)Who this might be right forLangerhans Cell Histiocytosis Baylor College of Medicine 124
Testing effectiveness (Phase 2)UnknownNCT04405375What this trial is testingGPED Regimen for Relapsed/Refractory or Advanced ENKTCLWho this might be right forExtranodal NK/T-cell Lymphoma, Nasal Type Beijing Tongren Hospital 29
Post-approval studies (Phase 4)UnknownNCT05284942What this trial is testingCentral China Rosai-Dorfman Disease RegistryWho this might be right forRosai-Dorfman DiseaseLangerhans Cell Histiocytosis Tongji Hospital 20
Testing effectiveness (Phase 2)Study completedNCT01104025What this trial is testingHybrid Immunotherapy for Hemophagocytic LymphoHistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Children's Hospital Medical Center, Cincinnati 31
Testing effectiveness (Phase 2)Study completedNCT03526250What this trial is testingPalbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)Who this might be right forAdvanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more National Cancer Institute (NCI) 23
Early research (Phase 1)UnknownNCT03893071What this trial is testingOpen-Label Study of Long-Term Safety and Efficacy of Intravenous Trappsol Cyclo (HPβCD) in Niemann-Pick Disease Type CWho this might be right forNiemann-Pick Disease, Type C1 Cyclo Therapeutics, Inc. 12
Not applicableActive Not RecruitingNCT07274826What this trial is testingDiagnostic Creteria of Acid Sphingomyelinase Deficiency (ASMD)Who this might be right forAcid Sphingomyelinase Deficiency (ASMD) Sohag University 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04195555What this trial is testingIvosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Who this might be right forRecurrent EpendymomaRecurrent Ewing SarcomaRecurrent Hepatoblastoma+30 more National Cancer Institute (NCI) 3
Early research (Phase 1)UnknownNCT05477446What this trial is testingSafety and Efficacy of CD207 Targeted CAR-T Cell Therapy in Patients With R/R Langerhans Cell HistiocytosisWho this might be right forLangerhans Cell Histiocytosis Beijing Friendship Hospital 12
Not applicableUnknownNCT06491719What this trial is testingA Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCTWho this might be right forCAEBV (Chronic Active Epstein-Barr Virus Infection) SyndromeEBVHemophagocytic Lymphohistiocytoses Beijing Friendship Hospital 15
Testing effectiveness (Phase 2)Ended earlyNCT04356690What this trial is testingEtoposide in Patients With COVID-19 InfectionWho this might be right forCOVID-19 Boston Medical Center 8
Not applicableActive Not RecruitingNCT07011329What this trial is testingBrain Alterations Based on Multiplex MR Imaging in Nasopharyngeal Carcinoma Patients After Treatment, and Their Correlation With Clinical Cognitive Scores.Who this might be right forNasopharyngeal Carcinoma (NPC) Hubei Cancer Hospital 60
Not applicableUnknownNCT05137522What this trial is testingChidamide Combines With VP-16 and Methylprednisolone in the Treatment of HLHWho this might be right forChidamideHemophagocytic Lymphohistiocytosis Beijing Friendship Hospital 20
Testing effectiveness (Phase 2)UnknownNCT00008164What this trial is testingUmbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic AnemiaWho this might be right forChildhood Langerhans Cell HistiocytosisLeukemiaLymphoma+3 more Herbert Irving Comprehensive Cancer Center 30
Not applicableUnknownNCT02120235What this trial is testingInvestigating Lysosomal Storage Diseases in Minority GroupsWho this might be right forLysosomal Storage DisordersGaucher DiseaseFabry Disease+2 more O & O Alpan LLC 20,000
Testing effectiveness (Phase 2)Looking for participantsNCT06582745What this trial is testingTargeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, TrametinibWho this might be right forLangerhans Cell Histiocytosis Cook Children's Health Care System 75
Testing effectiveness (Phase 2)Study completedNCT02004704What this trial is testingA Long-Term Study of Olipudase Alfa in Patients With Acid Sphingomyelinase DeficiencyWho this might be right forSphingomyelin Lipidosis Genzyme, a Sanofi Company 25
Large-scale testing (Phase 3)Ended earlyNCT03985423What this trial is testingEvaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLHWho this might be right forHemophagocytic Lymphohistiocytoses Swedish Orphan Biovitrum 7
Large-scale testing (Phase 3)Study completedNCT02004691What this trial is testingEfficacy, Safety, Pharmacodynamic, and Pharmacokinetics Study of Olipudase Alfa in Patients With Acid Sphingomyelinase DeficiencyWho this might be right forSphingomyelin Lipidosis Genzyme, a Sanofi Company 36