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Results for “Histiocytosis, Langerhans-cell”

259 trials

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Showing 20 of 259 results

Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Testing effectiveness (Phase 2)Ended earlyNCT01727206
What this trial is testing

Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease

Who this might be right for
Erdheim-Chester Disease
Ospedale San Raffaele 3
Testing effectiveness (Phase 2)WithdrawnNCT03687476
What this trial is testing

Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease

Who this might be right for
Niemann-Pick Disease, Type C
Vtesse, LLC, a Mallinckrodt Pharmaceuticals Company
Large-scale testing (Phase 3)Study completedNCT02069899
What this trial is testing

Long-term Follow-up of Hemophagocytic Lymphohistiocytosis (HLH) Participants Who Received Treatment With Emapalumab (NI-0501), an Anti-interferon Gamma Monoclonal Antibody

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Swedish Orphan Biovitrum 58
Testing effectiveness (Phase 2)Study completedNCT00919503
What this trial is testing

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Who this might be right for
Non-Neoplastic Hematologic and Lymphocytic Disorder
Fred Hutchinson Cancer Center 98
Large-scale testing (Phase 3)WithdrawnNCT00488605
What this trial is testing

H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis

Who this might be right for
Leukemia
University of New Mexico
Testing effectiveness (Phase 2)WithdrawnNCT02007239
What this trial is testing

Tocilizumab and Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Children's Hospital of Philadelphia
Not applicableStudy completedNCT00276757
What this trial is testing

Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis

Who this might be right for
Childhood Langerhans Cell Histiocytosis
Histiocyte Society 376
Not applicableUnknownNCT00005900
What this trial is testing

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Who this might be right for
I Cell DiseaseFucosidosisGloboid Cell Leukodystrophy+9 more
Fairview University Medical Center 10
Early research (Phase 1)Ended earlyNCT00410566
What this trial is testing

Safety Study of rhASM Enzyme Replacement Therapy in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease)

Who this might be right for
Acid Sphingomyelinase DeficiencyNiemann-Pick Disease
Genzyme, a Sanofi Company 11
Testing effectiveness (Phase 2)UnknownNCT04121819
What this trial is testing

AraC for Newly Diagnosed Adult Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytosis
Peking Union Medical College Hospital 40
Not applicableStudy completedNCT00001972
What this trial is testing

PET Scan of Brain Metabolism in Relation to Age and Disease

Who this might be right for
Alzheimer's DiseaseBrain NeoplasmNiemann Pick Disease
National Institute of Neurological Disorders and Stroke (NINDS) 123
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Looking for participantsNCT06153173
What this trial is testing

Mirdametinib in Histiocytic Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Juvenile Xanthogranuloma (JXG)Rosai-Dorfman Disease (RDD)+1 more
Children's Hospital Medical Center, Cincinnati 40
Testing effectiveness (Phase 2)Looking for participantsNCT07187193
What this trial is testing

Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

Who this might be right for
Langerhans Cell Histiocytosis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
Large-scale testing (Phase 3)Not Yet RecruitingNCT05775705
What this trial is testing

L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH

Who this might be right for
PD-1 AntibodyHemophagocytic LymphohistiocytosisEpstein-Barr Virus+1 more
Beijing Friendship Hospital 25
Large-scale testing (Phase 3)UnknownNCT03742115
What this trial is testing

Etoposide in the First-line Treatment of Adult EBV-HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 90
Testing effectiveness (Phase 2)Study completedNCT00588536
What this trial is testing

Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH

Who this might be right for
Langerhans Cell Histiocytosis
Memorial Sloan Kettering Cancer Center 5
Not applicableStudy completedNCT03052101
What this trial is testing

Assessment of Safety of Air Travel in Patients With Pulmonary Langerhans Cell Histiocytosis

Who this might be right for
Pulmonary Langerhans Cell Histiocytosis
University of Cincinnati 94
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