Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “HoFH”

83 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 83 results

Not applicableUnknownNCT03135184
What this trial is testing

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial HypercholesterolemiaHoFH
HDL Therapeutics 6
Large-scale testing (Phase 3)Study completedNCT04681170
What this trial is testing

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolaemia (HoFH)
Amryt Pharma 46
Large-scale testing (Phase 3)WithdrawnNCT02765841
What this trial is testing

Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT03933293
What this trial is testing

Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akeso 10
Large-scale testing (Phase 3)Study completedNCT02434497
What this trial is testing

Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 9
Testing effectiveness (Phase 2)Study completedNCT01412034
What this trial is testing

Effect of CER-001 on Plaque Volume in Homozygous Familial Hypercholesterolemia (HoFH) Subjects

Who this might be right for
Homozygous Familial Hypercholesterolemia
Cerenis Therapeutics, SA 23
Not applicableStudy completedNCT03018678
What this trial is testing

Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 21
Large-scale testing (Phase 3)Enrolling By InvitationNCT04798430
What this trial is testing

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction

Who this might be right for
Cardiovascular Disease With Mention of ArteriosclerosisElevated CholesterolFamilial Hypercholesterolemia
LIB Therapeutics LLC 2,000
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Post-approval studies (Phase 4)Study completedNCT03403374
What this trial is testing

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia HoFH
Amgen 30
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT02173158
What this trial is testing

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Aegerion Pharmaceuticals, Inc. 9
Large-scale testing (Phase 3)Study completedNCT03884452
What this trial is testing

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Who this might be right for
Familial Hypercholesterolemia
Organon and Co 50
Large-scale testing (Phase 3)Study completedNCT03409744
What this trial is testing

Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 116
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Large-scale testing (Phase 3)Active Not RecruitingNCT06712771
What this trial is testing

Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Visirna Therapeutics HK Limited 46
Large-scale testing (Phase 3)Study completedNCT03851705
What this trial is testing

Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 56
Not applicableApproved For MarketingNCT06500598
What this trial is testing

Compassionate Use of Evinacumab

Who this might be right for
Pediatric Homozygous Familial Hypercholesterolemia (HoFH)Severe Hypertriglyceridemia (HTG)Dysbetalipoproteinemia (DBL)
Regeneron Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Load More Results