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Results for “HoFH”

82 trials

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Showing 20 of 82 results

Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Not applicableLooking for participantsNCT04370899
What this trial is testing

Early Detection of Familial Hypercholesterolemia in Children

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia - HeterozygousFamilial Hypercholesterolemia - Homozygous
Institut Investigacio Sanitaria Pere Virgili 400
Testing effectiveness (Phase 2)Looking for participantsNCT07489209
What this trial is testing

A Dose-exploration Study of EDP167 in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Eddingpharm (Zhuhai) Co., Ltd. 20
Not applicableUnknownNCT03135184
What this trial is testing

HDL Acute Lipid Optimization in Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial HypercholesterolemiaHoFH
HDL Therapeutics 6
Large-scale testing (Phase 3)Study completedNCT05611528
What this trial is testing

Safety and Effectiveness of Evinacumab for the Treatment of Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Daniel Gaudet 10
Large-scale testing (Phase 3)Study completedNCT03851705
What this trial is testing

Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 56
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Large-scale testing (Phase 3)Study completedNCT02434497
What this trial is testing

Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 9
Large-scale testing (Phase 3)Study completedNCT04681170
What this trial is testing

Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolaemia (HoFH)
Amryt Pharma 46
Testing effectiveness (Phase 2)Study completedNCT04515927
What this trial is testing

To Evaluate the Efficacy and Safety of JS002 in HoFH Patients

Who this might be right for
Hyperlipemia
Shanghai Junshi Bioscience Co., Ltd. 31
Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Post-approval studies (Phase 4)Study completedNCT03403374
What this trial is testing

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia HoFH
Amgen 30
Not applicableStudy completedNCT03110432
What this trial is testing

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry

Who this might be right for
DyslipoproteinemiasHypercholesterolemia, FamilialFamilial Hypercholesterolemia - Homozygous+1 more
GWT-TUD GmbH 1,695
Large-scale testing (Phase 3)Not Yet RecruitingNCT06712771
What this trial is testing

Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Visirna Therapeutics HK Limited 45
Large-scale testing (Phase 3)Study completedNCT03885921
What this trial is testing

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Who this might be right for
Hypercholesterolemia
Organon and Co 44
Testing effectiveness (Phase 2)Active Not RecruitingNCT05217667
What this trial is testing

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 18
Not applicableLooking for participantsNCT04815005
What this trial is testing

HoFH, the International Clinical Collaborators Registry

Who this might be right for
Homozygous Familial Hypercholesterolemia
University of Pennsylvania 1,000
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
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