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Results for “Homozygous Familial Hypercholesterolaemia (HoFH)”

81 trials

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Showing 20 of 81 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07133815
What this trial is testing

Evaluate the Long-term Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 55
Testing effectiveness (Phase 2)Study completedNCT01556906
What this trial is testing

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Looking for participantsNCT07489209
What this trial is testing

A Dose-exploration Study of EDP167 in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Eddingpharm (Zhuhai) Co., Ltd. 20
Testing effectiveness (Phase 2)Study completedNCT06009393
What this trial is testing

Evaluate the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Beijing Suncadia Pharmaceuticals Co., Ltd 26
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Testing effectiveness (Phase 2)Study completedNCT04515927
What this trial is testing

To Evaluate the Efficacy and Safety of JS002 in HoFH Patients

Who this might be right for
Hyperlipemia
Shanghai Junshi Bioscience Co., Ltd. 31
Large-scale testing (Phase 3)Ended earlyNCT01841684
What this trial is testing

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

Who this might be right for
Hyperlipoproteinemia Type IIHomozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC 2
Large-scale testing (Phase 3)Study completedNCT00943306
What this trial is testing

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 19
Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Not applicableStudy completedNCT01878604
What this trial is testing

Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Central South University 5
Large-scale testing (Phase 3)Ended earlyNCT00263081
What this trial is testing

Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Takeda 44
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Testing effectiveness (Phase 2)Study completedNCT03933293
What this trial is testing

Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akeso 10
Large-scale testing (Phase 3)Study completedNCT00730236
What this trial is testing

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 29
Not applicableLooking for participantsNCT04370899
What this trial is testing

Early Detection of Familial Hypercholesterolemia in Children

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia - HeterozygousFamilial Hypercholesterolemia - Homozygous
Institut Investigacio Sanitaria Pere Virgili 400
Not applicableStudy completedNCT00704535
What this trial is testing

Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)

Who this might be right for
Primary HypercholesterolemiaHomozygous Familial Hypercholesterolemia
Organon and Co 4,105
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
Testing effectiveness (Phase 2)Study completedNCT02472535
What this trial is testing

Study to Evaluate the Effects of MBX-8025 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Gilead Sciences 13
Not applicableActive Not RecruitingNCT06832371
What this trial is testing

Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Major Adverse Cardiovascular Events (MACE)Dyslipidemia
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 73
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