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Results for “Homozygous Familial Hypercholesterolemia”

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Showing 20 of 85 results

Not applicableUnknownNCT04080050
What this trial is testing

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 8
Testing effectiveness (Phase 2)Ended earlyNCT05217667
What this trial is testing

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 18
Large-scale testing (Phase 3)Study completedNCT02434497
What this trial is testing

Evaluate the Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 9
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Not applicableActive Not RecruitingNCT06275724
What this trial is testing

Specified Drug-use Survey of Leqvio for s.c. Injection.

Who this might be right for
Familial HypercholesterolaemiaHypercholesterolaemia
Novartis Pharmaceuticals 585
Large-scale testing (Phase 3)Ended earlyNCT01841684
What this trial is testing

Efficacy and Tolerability of Anacetrapib Added to Ongoing Lipid-Lowering Therapy in Adult Participants With Homozygous Familial Hypercholesterolemia (HoFH) (MK-0859-042)

Who this might be right for
Hyperlipoproteinemia Type IIHomozygous Familial Hypercholesterolemia
Merck Sharp & Dohme LLC 2
Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Not applicableStudy completedNCT03234127
What this trial is testing

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Nantes University Hospital 562
Not applicableLooking for participantsNCT07447648
What this trial is testing

Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Coronary Computed Tomography Angiography
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 52
Not applicableStudy completedNCT04722068
What this trial is testing

Regeneron 1331 Kinetics Sub-Study HoFH

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 4
Post-approval studies (Phase 4)Study completedNCT03403374
What this trial is testing

Safety and Tolerability of Repatha® (Evolocumab) in Indian Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia HoFH
Amgen 30
Testing effectiveness (Phase 2)Study completedNCT02265952
What this trial is testing

Study of REGN1500 in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 9
Testing effectiveness (Phase 2)Study completedNCT00477594
What this trial is testing

Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia

Who this might be right for
Lipid Metabolism, Inborn ErrorsHypercholesterolemia, Autosomal DominantHyperlipidemias+11 more
Kastle Therapeutics, LLC 21
Not applicableStudy completedNCT04148001
What this trial is testing

Identifying and Genotyping Homozygous Familial Hypercholesterolemia (HoFH) Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 4
Not applicableStudy completedNCT00704444
What this trial is testing

A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)

Who this might be right for
HypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia
Organon and Co 11,332
Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Large-scale testing (Phase 3)Study completedNCT03156621
What this trial is testing

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 69
Very early researchLooking for participantsNCT06125847
What this trial is testing

NGGT006 Gene Therapy for Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
First Affiliated Hospital Xi'an Jiaotong University 21
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