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Results for “Homozygous Familial Hypercholesterolemia”

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Showing 20 of 85 results

Not applicableStudy completedNCT01878604
What this trial is testing

Gene Analysis and Treatment Optimization in Chinese Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Central South University 5
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT03884452
What this trial is testing

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Who this might be right for
Familial Hypercholesterolemia
Organon and Co 50
Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Large-scale testing (Phase 3)Study completedNCT03885921
What this trial is testing

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Who this might be right for
Hypercholesterolemia
Organon and Co 44
Large-scale testing (Phase 3)Ended earlyNCT00263081
What this trial is testing

Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Takeda 44
Large-scale testing (Phase 3)Study completedNCT00730236
What this trial is testing

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 29
Not applicableLooking for participantsNCT07447648
What this trial is testing

Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Coronary Computed Tomography Angiography
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 52
Not applicableStudy completedNCT00705211
What this trial is testing

A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)

Who this might be right for
HypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia
Organon and Co 1,794
Large-scale testing (Phase 3)Ended earlyNCT00092833
What this trial is testing

Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)

Who this might be right for
Hypercholesterolemia, FamilialLipid Metabolism, Inborn Errors
Organon and Co 49
Large-scale testing (Phase 3)Study completedNCT03851705
What this trial is testing

Inclisiran in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 56
Testing effectiveness (Phase 2)Study completedNCT04515927
What this trial is testing

To Evaluate the Efficacy and Safety of JS002 in HoFH Patients

Who this might be right for
Hyperlipemia
Shanghai Junshi Bioscience Co., Ltd. 31
Testing effectiveness (Phase 2)Study completedNCT01556906
What this trial is testing

Safety, Tolerability and Efficacy of Microsomal Triglyceride Protein (MTP) Inhibitor

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT03234127
What this trial is testing

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Nantes University Hospital 562
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Not applicableWithdrawnNCT03198897
What this trial is testing

Biomarker for Homozygous Familial Hypercholesterolemia (BioHoFH)

Who this might be right for
Lipoprotein Lipase DeficiencyInborn Error of Lipid MetabolismCorneal Arcus
CENTOGENE GmbH Rostock
Large-scale testing (Phase 3)Looking for participantsNCT05682378
What this trial is testing

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Who this might be right for
Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 195
Not applicableStudy completedNCT00704535
What this trial is testing

Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)

Who this might be right for
Primary HypercholesterolemiaHomozygous Familial Hypercholesterolemia
Organon and Co 4,105
Not applicableStudy completedNCT00704444
What this trial is testing

A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)

Who this might be right for
HypercholesterolemiaFamilial HypercholesterolemiaHomozygous Sitosterolemia
Organon and Co 11,332
Large-scale testing (Phase 3)Study completedNCT03156621
What this trial is testing

Study in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 69
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