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Results for “Homozygous Familial Hypercholesterolemia (HoFH)”

76 trials

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Showing 20 of 76 results

Not applicableLooking for participantsNCT01109368
What this trial is testing

The Rogosin Institute Homozygous Familial Hypercholesterolemia Repository

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Rogosin Institute 60
Large-scale testing (Phase 3)Study completedNCT03885921
What this trial is testing

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Who this might be right for
Hypercholesterolemia
Organon and Co 44
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Testing effectiveness (Phase 2)Study completedNCT02963311
What this trial is testing

ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
The Medicines Company 9
Testing effectiveness (Phase 2)UnknownNCT04455581
What this trial is testing

Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Jiangsu HengRui Medicine Co., Ltd. 8
Large-scale testing (Phase 3)Study completedNCT03814187
What this trial is testing

Trial to Assess the Effect of Long Term Dosing of Inclisiran in Subjects With High CV Risk and Elevated LDL-C

Who this might be right for
ASCVDElevated CholesterolHeterozygous Familial Hypercholesterolemia+1 more
Novartis Pharmaceuticals 3,275
Large-scale testing (Phase 3)Study completedNCT04233918
What this trial is testing

Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 20
Testing effectiveness (Phase 2)Study completedNCT04515927
What this trial is testing

To Evaluate the Efficacy and Safety of JS002 in HoFH Patients

Who this might be right for
Hyperlipemia
Shanghai Junshi Bioscience Co., Ltd. 31
Large-scale testing (Phase 3)WithdrawnNCT02765841
What this trial is testing

Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT00280995
What this trial is testing

Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowering Therapy

Who this might be right for
Hypercholesterolemia, Familial
Kastle Therapeutics, LLC 12
Not applicableUnknownNCT04080050
What this trial is testing

A Long-term Follow-up Study to Evaluate the Safety and Efficacy of RGX-501

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
REGENXBIO Inc. 8
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT03399786
What this trial is testing

Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 65
Large-scale testing (Phase 3)Study completedNCT04034485
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 65
Testing effectiveness (Phase 2)Study completedNCT02722408
What this trial is testing

Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)

Who this might be right for
Hypercholesteremia
NeuroBo Pharmaceuticals Inc. 8
Not applicableStudy completedNCT03234127
What this trial is testing

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Nantes University Hospital 562
Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Not applicableStudy completedNCT00704535
What this trial is testing

Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)

Who this might be right for
Primary HypercholesterolemiaHomozygous Familial Hypercholesterolemia
Organon and Co 4,105
Large-scale testing (Phase 3)Ended earlyNCT00263081
What this trial is testing

Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Takeda 44
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