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Results for “Human Papillomavirus-Negative Neck Squamous Cell Carcinoma”

50 trials

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Showing 20 of 50 results

Early research (Phase 1)Study completedNCT04670679
What this trial is testing

A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 90
Testing effectiveness (Phase 2)Looking for participantsNCT06448026
What this trial is testing

Cemiplimab and Cetuximab Prior Salvage Surgery in Patients With Recurrent Oral Cavity and HPV-negative Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Locally Recurrent Oral Cavity Squamous Cell Carcinoma
M.D. Anderson Cancer Center 17
Large-scale testing (Phase 3)WithdrawnNCT03673735
What this trial is testing

Maintenance Immune Check-point Inhibitor Following Post-operative Chemo-radiation in Subjects With HPV-negative HNSCC

Who this might be right for
Squamous Cell Head and Neck Carcinoma
European Organisation for Research and Treatment of Cancer - EORTC
Testing effectiveness (Phase 2)WithdrawnNCT05879484
What this trial is testing

Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS

Who this might be right for
Sinonasal CancerSquamous Non-small Cell Lung CancerLung Cancer+3 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT03953443
What this trial is testing

Expression & Epigenetic Silencing of MicroRNA for Predicting Therapeutic Response and Prognosis of HPV-negative HNSCC

Who this might be right for
Head and Neck Squamous Cell Carcinoma
New Mexico Cancer Research Alliance 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Looking for participantsNCT07513389
What this trial is testing

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

Who this might be right for
Squamous Cell CarcinomaHuman Papilloma Virus (HPV)Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Medical University of South Carolina 36
Testing effectiveness (Phase 2)Looking for participantsNCT06636734
What this trial is testing

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more
Emory University
Testing effectiveness (Phase 2)Looking for participantsNCT06935188
What this trial is testing

Dalpicilib Plus Cetuximab Compared With Cetuximab Alone in HPV-negative, Anti-PD-1-resistant R/M HNSCC

Who this might be right for
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 98
Testing effectiveness (Phase 2)WithdrawnNCT05608369
What this trial is testing

Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC

Who this might be right for
HPV-Related Squamous Cell CarcinomaSquamous Cell Carcinoma of the Oral CavitySquamous Cell Carcinoma of the Larynx+2 more
Case Comprehensive Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT04220749
What this trial is testing

Radiotherapy vs. Trans-Oral Surgery for HPV-Negative Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Head and Neck CancerOropharyngeal Squamous Cell Carcinoma
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 68
Testing effectiveness (Phase 2)Study completedNCT01807546
What this trial is testing

Oral Rigosertib for Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaAnal Squamous Cell CarcinomaLung Squamous Cell Carcinoma+4 more
Traws Pharma, Inc. 64
Testing effectiveness (Phase 2)Study completedNCT02499120
What this trial is testing

Safety And Efficacy Study Of Palbociclib Plus Cetuximab Versus Cetuximab To Treat Head And Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Pfizer 125
Testing effectiveness (Phase 2)Active Not RecruitingNCT05366166
What this trial is testing

Pembrolizumab Plus Olaparib in LA-HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
UNC Lineberger Comprehensive Cancer Center 45
Not applicableActive Not RecruitingNCT07407205
What this trial is testing

Tumor Mutational Burden, Liquid Biopsy, Angiogenic Factors and DCE-MRI Perfusion in HPV-Negative Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaOropharyngeal HPV Squamous Cell Carcinoma
Institute of Oncology Ljubljana 30
Very early researchWithdrawnNCT05845307
What this trial is testing

Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Looking for participantsNCT06161545
What this trial is testing

Pembrolizumab + N-803 Alone or in Combination With PD-L1 t-haNK Cells for Resectable Head and Neck Squamous Cell Carcinoma

Who this might be right for
Stage II Squamous Cell Carcinoma of the Head and NeckStage III Squamous Cell Carcinoma of the Head and NeckStage IV Squamous Cell Carcinoma of the Head and Neck
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Ended earlyNCT02540928
What this trial is testing

AMG 319 in HPV Positive and Negative HNSCC

Who this might be right for
Human Papillomavirus (HPV)Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Cancer Research UK 35
Testing effectiveness (Phase 2)Study completedNCT02207439
What this trial is testing

Phase II Trial of Nelfinavir With Concurrent Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 18
Testing effectiveness (Phase 2)Ended earlyNCT04169074
What this trial is testing

Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial)

Who this might be right for
HNSCC
University of Arizona 7
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