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Results for “Hyperammonemia”

36 trials

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Showing 20 of 36 results

Large-scale testing (Phase 3)Looking for participantsNCT06255782
What this trial is testing

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency

Who this might be right for
Ornithine Transcarbamylase DeficiencyOrnithine Transcarbamylase Deficiency DiseaseOrnithine Carbamoyltransferase Deficiency (Disorder)+1 more
iECURE, Inc. 20
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Not applicableLooking for participantsNCT05754372
What this trial is testing

Optimalisation of the Treatment of Acute Neonatal Hyperammonaemia

Who this might be right for
Hyperammonemic Encephalopathy
University Hospital, Ghent 10
Not applicableLooking for participantsNCT05040178
What this trial is testing

An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

Who this might be right for
HyperammonemiaMethylmalonic AcidemiaPropionic Acidemia
RECORDATI GROUP 20
Not applicableLooking for participantsNCT07499349
What this trial is testing

Establishment of a Phamacokinetik Model for Erwinase Pharmacokinetiks: The Aim of This Sub Study is to Optimize Target Trough Attainment While Minimizing High Exposures That Impose Increased Risk of Side Effects Such as Hyperammonemia

Who this might be right for
Acute Lymphoblastic Leukemia
Aarhus University Hospital 475
Early research (Phase 1)Ended earlyNCT05349435
What this trial is testing

A Healthy Volunteer Study to Compare Fezagepras (PBI-4050) With Sodium Phenylbutyrate

Who this might be right for
Hyperammonemia
Liminal BioSciences Ltd. 8
Not applicableStudy completedNCT06721845
What this trial is testing

Non-Cirrhotic Hyperammonemia Versus Hyperlactatemia in Septic Patients and Impact of Treatment

Who this might be right for
Sepsis
Menoufia University 60
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Study completedNCT00947544
What this trial is testing

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Amgen 17
Testing effectiveness (Phase 2)Study completedNCT01599286
What this trial is testing

Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia

Who this might be right for
Propionic Acidemia, Type I and/or Type IIMethylmalonic AcidemiaCarbamoyl-Phosphate Synthase I Deficiency Disease+1 more
Mendel Tuchman 35
Testing effectiveness (Phase 2)WithdrawnNCT03884959
What this trial is testing

A Safety and Efficacy Study of Infusions of HepaStem in Urea Cycle Disorders Pediatric Patients

Who this might be right for
Urea Cycle Disorder
HLB Cell Co., Ltd.
Testing effectiveness (Phase 2)Study completedNCT01624311
What this trial is testing

Pilot Study For Hypothermia Treatment In Hyperammonemic Encephalopathy In Neonates And Very Young Infants

Who this might be right for
Urea Cycle DisordersOrganic Acidemias
Uta Lichter-Konecki 5
Not applicableStudy completedNCT01569568
What this trial is testing

Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI

Who this might be right for
Ornithine Transcarbamylase Deficiency
Andrea Gropman 49
Testing effectiveness (Phase 2)WithdrawnNCT04984798
What this trial is testing

Vitamin E Efficacy in HI/HA

Who this might be right for
Hyperinsulinism-Hyperammonemia Syndrome
Children's Hospital of Philadelphia
Large-scale testing (Phase 3)WithdrawnNCT04128462
What this trial is testing

MNK-6105 for Patients With Cirrhosis and High Ammonia Levels Affecting Brain Function

Who this might be right for
Hepatic Encephalopathy
Mallinckrodt
Post-approval studies (Phase 4)Study completedNCT01257737
What this trial is testing

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Who this might be right for
Urea Cycle Disorders
Amgen 88
Not applicableLooking for participantsNCT06600659
What this trial is testing

Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmAcute Lymphobkastic Leukemia
Mayo Clinic 10
Not applicableEnrolling By InvitationNCT06041906
What this trial is testing

International Registry of Congenital Portosystemic Shunt (IRCPSS)

Who this might be right for
Congenital Portosystemic ShuntCPSS (Congenital Portosystemic Shunt)
Prof. Valérie Mc Lin 500
Not applicableEnrolling By InvitationNCT06987604
What this trial is testing

Continuous Renal Replacement Therapy Intensity in Hyperammonemia

Who this might be right for
Acute Liver FailureAcute on Chronic Liver Failure (ACLF)Acute Kidney Injury+1 more
Hospital de Clinicas de Porto Alegre 152
Early research (Phase 1)Study completedNCT06178718
What this trial is testing

Evaluate PK Profile and Food Effects on PK Parameters of TNP-2092 Capsules

Who this might be right for
Hyperammonemia
TenNor Therapeutics (Suzhou) Limited 58
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