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Results for “Hyperammonemia”

36 trials

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Showing 20 of 36 results

Not applicableEnrolling By InvitationNCT06041906
What this trial is testing

International Registry of Congenital Portosystemic Shunt (IRCPSS)

Who this might be right for
Congenital Portosystemic ShuntCPSS (Congenital Portosystemic Shunt)
Prof. Valérie Mc Lin 500
Post-approval studies (Phase 4)Study completedNCT02246218
What this trial is testing

The Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorder
Amgen 27
Testing effectiveness (Phase 2)Study completedNCT01599286
What this trial is testing

Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia

Who this might be right for
Propionic Acidemia, Type I and/or Type IIMethylmalonic AcidemiaCarbamoyl-Phosphate Synthase I Deficiency Disease+1 more
Mendel Tuchman 35
Not applicableStudy completedNCT06721845
What this trial is testing

Non-Cirrhotic Hyperammonemia Versus Hyperlactatemia in Septic Patients and Impact of Treatment

Who this might be right for
Sepsis
Menoufia University 60
Not applicableLooking for participantsNCT05754372
What this trial is testing

Optimalisation of the Treatment of Acute Neonatal Hyperammonaemia

Who this might be right for
Hyperammonemic Encephalopathy
University Hospital, Ghent 10
Not applicableStudy completedNCT04771104
What this trial is testing

The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis

Who this might be right for
Hepatic EncephalopathyLiver CirrhosisSleep Disturbance
Rigshospitalet, Denmark 9
Not applicableWithdrawnNCT00279851
What this trial is testing

Blood Sugars in Children With Idiopathic Seizures.

Who this might be right for
SeizuresHypoglycemiaHyperammonemia
Children's Mercy Hospital Kansas City
Testing effectiveness (Phase 2)Study completedNCT00947544
What this trial is testing

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders

Who this might be right for
Urea Cycle Disorders
Amgen 17
Not applicableStudy completedNCT01569568
What this trial is testing

Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI

Who this might be right for
Ornithine Transcarbamylase Deficiency
Andrea Gropman 49
Not applicableEnrolling By InvitationNCT06987604
What this trial is testing

Continuous Renal Replacement Therapy Intensity in Hyperammonemia

Who this might be right for
Acute Liver FailureAcute on Chronic Liver Failure (ACLF)Acute Kidney Injury+1 more
Hospital de Clinicas de Porto Alegre 152
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)WithdrawnNCT03884959
What this trial is testing

A Safety and Efficacy Study of Infusions of HepaStem in Urea Cycle Disorders Pediatric Patients

Who this might be right for
Urea Cycle Disorder
HLB Cell Co., Ltd.
Testing effectiveness (Phase 2)Study completedNCT01966419
What this trial is testing

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)

Who this might be right for
Acute Episode of Overt Hepatic EncephalopathyHepatic Encephalopathy
Ocera Therapeutics, Inc. 231
Early research (Phase 1)Ended earlyNCT05349435
What this trial is testing

A Healthy Volunteer Study to Compare Fezagepras (PBI-4050) With Sodium Phenylbutyrate

Who this might be right for
Hyperammonemia
Liminal BioSciences Ltd. 8
Not applicableLooking for participantsNCT07499349
What this trial is testing

Establishment of a Phamacokinetik Model for Erwinase Pharmacokinetiks: The Aim of This Sub Study is to Optimize Target Trough Attainment While Minimizing High Exposures That Impose Increased Risk of Side Effects Such as Hyperammonemia

Who this might be right for
Acute Lymphoblastic Leukemia
Aarhus University Hospital 475
Not applicableEnded earlyNCT02059356
What this trial is testing

Ammonia Levels and Cognitive Impairment

Who this might be right for
DementiaCognitive DeclineCognitive Impairment+1 more
Duke University 17
Not applicableStudy completedNCT04022941
What this trial is testing

Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.

Who this might be right for
Chronic Liver Disease
Institute of Liver and Biliary Sciences, India 108
Not applicableLooking for participantsNCT04602325
What this trial is testing

Systemic Biomarkers of Brain Injury From Hyperammonemia

Who this might be right for
Urea Cycle DisorderOrganic AcidemiaMaple Syrup Urine Disease+3 more
Children's National Research Institute 24
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Early research (Phase 1)Study completedNCT00645879
What this trial is testing

Anaplerotic Therapy in Propionic Acidemia

Who this might be right for
Propionic Acidemia
Nicola Longo 3
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