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Results for “Hypercholesterolemia, Familial, 3”

29 trials

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Showing 20 of 29 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07473843
What this trial is testing

Study of Zodasiran in Adolescent Participants With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 12
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)WithdrawnNCT02765841
What this trial is testing

Evaluate the Efficacy and Safety of Lomitapide in Pediatric Patients With Homozygous Familial Hypercholesterolemia on Stable Lipid-lowering Therapy

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc.
Large-scale testing (Phase 3)Study completedNCT05952856
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 2,912
Large-scale testing (Phase 3)Study completedNCT04233918
What this trial is testing

Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 20
Large-scale testing (Phase 3)Study completedNCT05425745
What this trial is testing

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+6 more
NewAmsterdam Pharma 354
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Large-scale testing (Phase 3)Active Not RecruitingNCT06712771
What this trial is testing

Clinical Trial to Evaluate the Efficacy and Safety of VSA003 in Chinese HoFH Patients

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
Visirna Therapeutics HK Limited 46
Large-scale testing (Phase 3)Looking for participantsNCT07614958
What this trial is testing

Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days

Who this might be right for
Mixed DyslipidemiaHypercholesterolaemia
A. Menarini International Licensing S.A. 426
Large-scale testing (Phase 3)Study completedNCT01475825
What this trial is testing

The Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol

Who this might be right for
HypercholesterolemiaHeterozygous Familial
Kastle Therapeutics, LLC 309
Large-scale testing (Phase 3)Study completedNCT01968980
What this trial is testing

A 52 Week Study To Assess The Use Of Bococizumab (PF-04950615; RN316) In Subjects With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Pfizer 370
Large-scale testing (Phase 3)Study completedNCT00136981
What this trial is testing

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 800
Large-scale testing (Phase 3)Study completedNCT00134511
What this trial is testing

Study To Evaluate The Effect Of Torcetrapib/Atorvastatin In Patients With Genetic High Cholesterol Disorder

Who this might be right for
Hypercholesterolemia, Familial
Pfizer 30
Large-scale testing (Phase 3)Study completedNCT02173158
What this trial is testing

Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering Therapy

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Aegerion Pharmaceuticals, Inc. 9
Large-scale testing (Phase 3)Study completedNCT00134485
What this trial is testing

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Who this might be right for
Hypercholesterolemia, FamilialHyperlipidemia
Pfizer 400
Large-scale testing (Phase 3)Study completedNCT04797104
What this trial is testing

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction

Who this might be right for
Heterozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 478
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Large-scale testing (Phase 3)Looking for participantsNCT07037771
What this trial is testing

Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Arrowhead Pharmaceuticals 60
Early research (Phase 1)Looking for participantsNCT07491172
What this trial is testing

A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias

Who this might be right for
CardiovascularMetabolic DiseaseDyslipidemias+7 more
CRISPR Therapeutics AG 90
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