Post-approval studies (Phase 4)UnknownNCT02616354What this trial is testingPreliminary Research On Two-step Dosing Of Imipenem/CilastatinWho this might be right forSepsis Southeast University, China 24
Large-scale testing (Phase 3)UnknownNCT05204368What this trial is testingEvaluation of the Efficacy and Safety of Intravenous Imipenem/Cilastatin/XNW4107 in Comparison With Meropenem in Hospitalized Adults With cUTI Including AP (EudraCT no. 2022-000061-40)Who this might be right forComplicated Urinary Tract Infection Including Acute Pyelonephritis Evopoint Biosciences Inc. 780
Not applicableUnknownNCT04196608What this trial is testingIn Vitro Activity of Ceftolozane/Tazobactam and Imipenem/Relebactam in Clinical Isolates of Pseudomonas Aeruginosa and Enterobacterales Collected From Hematology and Oncology PatientsWho this might be right forCeftolozane/TazobactamImipenem/RelebactamHematology and Oncology Emilio Bouza 1,005
Large-scale testing (Phase 3)Study completedNCT00236834What this trial is testingThe Safety and Effectiveness of Levofloxacin Compared With Imipenem/Cilastatin in Patients With Pneumonia Acquired During HospitalizationWho this might be right forNosocomial Pneumonia Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 438
Large-scale testing (Phase 3)Study completedNCT03293485What this trial is testingEfficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)Who this might be right forComplicated Intra-abdominal InfectionComplicated Urinary Tract Infection Merck Sharp & Dohme LLC 83
Not applicableUnknownNCT02670239What this trial is testingPharmacokinetics of Imipenem During Ex Vivo Lung Perfusion (EVLP)Who this might be right forLung Transplantation University of Turin, Italy 30
Testing effectiveness (Phase 2)Study completedNCT02321800What this trial is testingEfficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract InfectionsWho this might be right forUrinary Tract Infections Shionogi 452
Not applicableUnknownNCT01374256What this trial is testingImipenem and Sulbactam in the Treatment of Imipenem-resistant Acinetobacter Baumannii BacteremiaWho this might be right forAcinetobacter Bacteraemia Taipei Veterans General Hospital, Taiwan 200
Not applicableUnknownNCT03858387What this trial is testingPK/PD and Clinial Outcomes of Beta-lactams in ICU PatientsWho this might be right forCritical IllnessBacterial Infections Prince of Songkla University 102
Large-scale testing (Phase 3)Study completedNCT05204563What this trial is testingImipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2)Who this might be right forHospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia Evopoint Biosciences Inc. 450
Large-scale testing (Phase 3)Study completedNCT03583333What this trial is testingImipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)Who this might be right forHospital-Acquired Bacterial PneumoniaVentilator-Associated Bacterial Pneumonia Merck Sharp & Dohme LLC 274
Testing effectiveness (Phase 2)Study completedNCT04983901What this trial is testingPHASE II SINGLE-CENTER, RANDOMIZED, OPEN-LABEL, PROSPECTIVE, STUDY TO DETERMINE THE IMPACT OF SERIAL PROCALCITONINWho this might be right forHematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm M.D. Anderson Cancer Center 100
Early research (Phase 1)Study completedNCT04147221What this trial is testingImipenem-Relebactam Pharmacokinetics in Augmented Renal ClearanceWho this might be right forSepsis Hartford Hospital 9
Not applicableStudy completedNCT00443885What this trial is testingResistance Rates and Mechanisms of Resistance to Imipenem and Meropenem at UPMCWho this might be right forGram Negative Organism University of Pittsburgh 500
Large-scale testing (Phase 3)Study completedNCT02493764What this trial is testingImipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)Who this might be right forBacterial Pneumonia Merck Sharp & Dohme LLC 537
Large-scale testing (Phase 3)Ended earlyNCT00589693What this trial is testingTo Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated PneumoniaWho this might be right forVentilator-Associated Pneumonia Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 274
Not applicableStudy completedNCT05048693What this trial is testingUse of New Antibiotics in SwedenWho this might be right forMulti-antibiotic Resistance Uppsala University 41
Large-scale testing (Phase 3)Study completedNCT03969901What this trial is testingSafety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)Who this might be right forSuspected or Documented Gram-negative Bacterial Infection Merck Sharp & Dohme LLC 115
Post-approval studies (Phase 4)UnknownNCT03776305What this trial is testingImipenem in Critically Ill PatientsWho this might be right forCritically Ill Patients With ECMO Prince of Songkla University 12
Post-approval studies (Phase 4)Study completedNCT01721408What this trial is testingDetermine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal InfectionWho this might be right forIntra-abdominal Infection Pfizer 470