Large-scale testing (Phase 3)Ended earlyNCT00430677What this trial is testingEfficacy and Safety Study of Abatacept to Treat Lupus NephritisWho this might be right forSystemic Lupus Erythematosus Bristol-Myers Squibb 423
Post-approval studies (Phase 4)Looking for participantsNCT07746895What this trial is testingReal-World Effectiveness and Safety of Pegcetacoplan in Patients With C3G or IC-MPG: A Multi-Country StudyWho this might be right forC3 Glomerulopathy (C3G)Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) Swedish Orphan Biovitrum 150
Not applicableStudy completedNCT00876616What this trial is testingAssess the Efficacy and Safety of Multi-target Therapy in Lupus NephritisWho this might be right forLupus Nephritis Zhi-Hong Liu, M.D. 362
Testing effectiveness (Phase 2)Looking for participantsNCT06434363What this trial is testingPhase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune DisordersWho this might be right forAutoimmune DisordersSystemic SclerosisSystemic Lupus Erythematosus+2 more M.D. Anderson Cancer Center 47
Testing effectiveness (Phase 2)Study completedNCT03610516What this trial is testingSafety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.Who this might be right forLupus Nephritis Novartis Pharmaceuticals 57
Testing effectiveness (Phase 2)Active Not RecruitingNCT06786338What this trial is testingSGB-9768 in Patients With Complement-mediated Kidney DiseasesWho this might be right forIgA Nephropathy (IgAN)C3 GlomerulopathyIC-MPGN Suzhou Sanegene Bio Inc. 45
Early research (Phase 1)Looking for participantsNCT06308978What this trial is testingFT819 in B-cell Mediated Autoimmune DiseaseWho this might be right forAntineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV)Idiopathic Inflammatory Myositis (IIM)Systemic Sclerosis (SSc)+2 more Fate Therapeutics 244
Testing effectiveness (Phase 2)Looking for participantsNCT07375758What this trial is testingMIL116 in Healthy Participants and Patients With IgA Nephropathy.Who this might be right forImmunoglobulin A Nephropathy Beijing Mabworks Biotech Co., Ltd. 130
Post-approval studies (Phase 4)Looking for participantsNCT07225387What this trial is testingSafety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy TrialWho this might be right forLupus Nephritis NephroNet, Inc. 30
Early research (Phase 1)Study completedNCT06004947What this trial is testingA Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant MedicationsWho this might be right forAnti-neutrophil Cytoplasmic Antibody-associated Vasculitis Amgen 32
Testing effectiveness (Phase 2)Study completedNCT00050713What this trial is testingSirolimus Therapy for Idiopathic and Lupus Membranous NephropathyWho this might be right forMembranous GlomerulonephritisLupus Membranous Nepropathy National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12
Post-approval studies (Phase 4)Looking for participantsNCT07760480What this trial is testingAssessing Residual Inflammation and Macrophage Presence in Lupus Nephritis After 3 Months of Intensified Treatment With Prednisolone, Mycofenolate Mofetil and Voclosporin as Compared to Mycofenolate Mofetil and PrednisoloneWho this might be right forLupus NephritisSystemic Lupus Erythematosus (SLE) Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 55
Not applicableLooking for participantsNCT02954939What this trial is testingThe Effect of Mycophenolate Mofetil and Cyclophosphamide on the Lymphocyte Subsets in Patients With Proliferative Lupus NephritisWho this might be right forLupus Nephritis The University of Hong Kong 50
Early research (Phase 1)WithdrawnNCT00583427What this trial is testingSulodexide Treatment in Patients With Dense Deposit DiseaseWho this might be right forDense Deposit Disease University of Iowa
Testing effectiveness (Phase 2)Ended earlyNCT05938725What this trial is testingKYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus NephritisWho this might be right forLupus NephritisLupus Nephritis - World Health Organization (WHO) Class IIILupus Nephritis - WHO Class IV Kyverna Therapeutics 6
Not applicableUnknownNCT05797038What this trial is testingStudy on the Application of Hyperspectral Imaging Technique in the Treatment of IMN by TACWho this might be right forIdiopathic Membranous NephropathyTacrolimusHyperspectral Imaging Qianfoshan Hospital 40
Very early researchLooking for participantsNCT07107659What this trial is testingSafety and Efficacy of ONT01 in LupusWho this might be right forLupus Nephritis (LN)Lupus Nephritis - WHO Class IIILupus Nephritis - WHO Class IV+5 more Hospital for Special Surgery, New York 61
Testing effectiveness (Phase 2)Study completedNCT01584388What this trial is testingRituximab in IgG4-RD: A Phase 1-2 TrialWho this might be right forRetroperitoneal FibrosisAutoimmune PancreatitisSialadenitis+1 more Massachusetts General Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05732402What this trial is testingAn Open-label Study of Povetacicept in Autoantibody-Associated Glomerular DiseasesWho this might be right forLupus NephritisImmunoglobulin A NephropathyMembranous Nephropathy+1 more Alpine Immune Sciences, Inc. 72
Large-scale testing (Phase 3)WithdrawnNCT05609812What this trial is testingAtacicept in Subjects With Active Lupus Nephritis (COMPASS)Who this might be right forLupus Nephritis (LN) Vera Therapeutics, Inc.