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Results for “LRRK2”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Study completedNCT05009199
What this trial is testing

Occupancy of Adenosine A2A Receptors Using the PET Radiotracer [18F]MNI-444

Who this might be right for
Healthy Volunteer
Invicro 3
Testing effectiveness (Phase 2)Looking for participantsNCT06680830
What this trial is testing

Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Who this might be right for
Parkinson DiseaseParkinsonIdiopathic Parkinson Disease+2 more
Neuron23 Inc. 150
Not applicableStudy completedNCT01860118
What this trial is testing

LRRK2 and Other Novel Exosome Proteins in Parkinson's Disease

Who this might be right for
Parkinson's Disease
University of Alabama at Birmingham 601
Testing effectiveness (Phase 2)Looking for participantsNCT06602193
What this trial is testing

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

Who this might be right for
Parkinson Disease
Denali Therapeutics Inc. 50
Not applicableUnknownNCT01089283
What this trial is testing

Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients With Different Genetic Characteristics

Who this might be right for
Parkinson Disease
Tel-Aviv Sourasky Medical Center 80
Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Not applicableStudy completedNCT01085227
What this trial is testing

Clinical, Molecular and by Neuroimaging of LRRK2 Mutations

Who this might be right for
Parkinson's Disease
Institut National de la Santé Et de la Recherche Médicale, France 50
Not applicableEnded earlyNCT00467090
What this trial is testing

Characteristics of Parkinson s Disease Associated With the LRRK-2 Gene Mutation

Who this might be right for
Parkinson Disease
National Institute of Neurological Disorders and Stroke (NINDS) 34
Large-scale testing (Phase 3)Ended earlyNCT05418673
What this trial is testing

Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale

Who this might be right for
Parkinson Disease
Biogen 7
Not applicableUnknownNCT04436848
What this trial is testing

LRRK2 G2385R Leucocyte and Urine Biomarker Study

Who this might be right for
Parkinson Disease
University of Malaya 150
Not applicableStudy completedNCT03775447
What this trial is testing

Fox BioNet Project: ECV-003

Who this might be right for
Parkinson Disease
Michael J. Fox Foundation for Parkinson's Research 38
Not applicableStudy completedNCT05287620
What this trial is testing

Objective, Passive Assessment of LRRK2 Carriers

Who this might be right for
Parkinson Disease
University of Rochester 10
Testing effectiveness (Phase 2)Looking for participantsNCT07020026
What this trial is testing

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

Who this might be right for
Parkinson's Disease
Michael J. Fox Foundation for Parkinson's Research 60
Not applicableLooking for participantsNCT03523104
What this trial is testing

Chinese PD-LRRK2 Registry

Who this might be right for
Parkinson Disease
Xiangya Hospital of Central South University 1,000
Not applicableUnknownNCT04214509
What this trial is testing

LIPAD - LRRK2 International Parkinson's Disease Study

Who this might be right for
Parkinson's Disease and Parkinsonism
University of Luebeck 4,000
Not applicableStudy completedNCT01536821
What this trial is testing

PROGENI (Parkinson's Research: The Organized Genetics Initiative) Family Study of LRRK2 (Leucine-rich Repeat Kinase 2)

Who this might be right for
Parkinson Disease
Indiana University 81
Early research (Phase 1)Study completedNCT04056689
What this trial is testing

Study to Evaluate DNL151 in Subjects With Parkinson's Disease

Who this might be right for
Parkinson's Disease
Biogen 36
Post-approval studies (Phase 4)UnknownNCT05355064
What this trial is testing

Efficacy of Oral Administration of Trehalose in Patients With Parkinson Disease

Who this might be right for
Parkinson Disease
Neuromed IRCCS 20
Not applicableUnknownNCT02319382
What this trial is testing

Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET

Who this might be right for
Parkinson's Disease With LRRK2 MutationHealthy ControlsParkinson's Disease Without LRRK2 Mutation
Assistance Publique - Hôpitaux de Paris 46
Not applicableUnknownNCT04387812
What this trial is testing

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation
Tel-Aviv Sourasky Medical Center 240
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