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Results for “LRRK2”

33 trials

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Showing 20 of 33 results

Not applicableNot Yet RecruitingNCT06993142
What this trial is testing

Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage

Who this might be right for
Parkinson DiseaseProdromal StageNeurodegenerative Diseases+8 more
Radboud University Medical Center 600
Not applicableEnded earlyNCT05349019
What this trial is testing

A Natural History Study of Patients With G2019S LRRK2 Parkinson's Disease

Who this might be right for
Patients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene
Escape Bio, Inc. 22
Early research (Phase 1)Ended earlyNCT01424475
What this trial is testing

LRRK2 Mutation and Parkinson's Disease

Who this might be right for
Parkinson Disease
GlaxoSmithKline 5
Not applicableUnknownNCT02319382
What this trial is testing

Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET

Who this might be right for
Parkinson's Disease With LRRK2 MutationHealthy ControlsParkinson's Disease Without LRRK2 Mutation
Assistance Publique - Hôpitaux de Paris 46
Not applicableStudy completedNCT04603326
What this trial is testing

FoxBioNet: ECV (Extracellular Vesicle) 004

Who this might be right for
Parkinson Disease
Michael J. Fox Foundation for Parkinson's Research 140
Large-scale testing (Phase 3)Ended earlyNCT05418673
What this trial is testing

Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale

Who this might be right for
Parkinson Disease
Biogen 7
Not applicableUnknownNCT01089283
What this trial is testing

Ioflupane I123 (DaTSCAN) and Positron Emission Tomography-computed Tomography Fludeoxyglucose (PET-CT FDG) to Assess Brain Function of Parkinson Patients With Different Genetic Characteristics

Who this might be right for
Parkinson Disease
Tel-Aviv Sourasky Medical Center 80
Not applicableEnded earlyNCT00467090
What this trial is testing

Characteristics of Parkinson s Disease Associated With the LRRK-2 Gene Mutation

Who this might be right for
Parkinson Disease
National Institute of Neurological Disorders and Stroke (NINDS) 34
Not applicableEnded earlyNCT04919356
What this trial is testing

Parkinson's Disease G2019S LRRK2 Genetic Testing Program

Who this might be right for
Parkinson's Disease
Escape Bio, Inc. 836
Testing effectiveness (Phase 2)Looking for participantsNCT07020026
What this trial is testing

Evaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's Disease

Who this might be right for
Parkinson's Disease
Michael J. Fox Foundation for Parkinson's Research 60
Not applicableActive Not RecruitingNCT03866603
What this trial is testing

Rostock International Parkinson's Disease Study (ROPAD)

Who this might be right for
Parkinson´s Disease
CENTOGENE GmbH Rostock 25,000
Not applicableLooking for participantsNCT03523104
What this trial is testing

Chinese PD-LRRK2 Registry

Who this might be right for
Parkinson Disease
Xiangya Hospital of Central South University 1,000
Not applicableEnded earlyNCT01618383
What this trial is testing

Study of the Enteric Nervous System Using Colonic Biopsies in Parkinson Patients With LRRK2 Mutation

Who this might be right for
Parkinson's Disease
Nantes University Hospital 19
Not applicableStudy completedNCT03782753
What this trial is testing

Molecular Pathology and Neuronal Networks in LRRK2 Parkinson's Disease

Who this might be right for
Parkinson Disease, PARK8Parkinson DiseaseIdiopathic Parkinson Disease
King's College London 59
Not applicableStudy completedNCT01860118
What this trial is testing

LRRK2 and Other Novel Exosome Proteins in Parkinson's Disease

Who this might be right for
Parkinson's Disease
University of Alabama at Birmingham 601
Testing effectiveness (Phase 2)Looking for participantsNCT06680830
What this trial is testing

NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Who this might be right for
Parkinson DiseaseParkinsonIdiopathic Parkinson Disease+2 more
Neuron23 Inc. 150
Not applicableStudy completedNCT03775447
What this trial is testing

Fox BioNet Project: ECV-003

Who this might be right for
Parkinson Disease
Michael J. Fox Foundation for Parkinson's Research 38
Not applicableUnknownNCT04387812
What this trial is testing

Evaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's Disease

Who this might be right for
Parkinson DiseaseGBA Gene MutationLeucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation
Tel-Aviv Sourasky Medical Center 240
Early research (Phase 1)Study completedNCT04056689
What this trial is testing

Study to Evaluate DNL151 in Subjects With Parkinson's Disease

Who this might be right for
Parkinson's Disease
Biogen 36
Testing effectiveness (Phase 2)Looking for participantsNCT06602193
What this trial is testing

Safety and Pharmacodynamic Effects of BIIB122 in Participants With LRRK2-Associated Parkinson's Disease (LRRK2-PD)

Who this might be right for
Parkinson Disease
Denali Therapeutics Inc. 50
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