Early research (Phase 1)Study completedNCT03710707What this trial is testingStudy to Evaluate DNL201 in Subjects With Parkinson's DiseaseWho this might be right forParkinson Disease Denali Therapeutics Inc. 29
Early research (Phase 1)Ended earlyNCT01424475What this trial is testingLRRK2 Mutation and Parkinson's DiseaseWho this might be right forParkinson Disease GlaxoSmithKline 5
Not applicableEnded earlyNCT05349019What this trial is testingA Natural History Study of Patients With G2019S LRRK2 Parkinson's DiseaseWho this might be right forPatients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene Escape Bio, Inc. 22
Not applicableUnknownNCT01730599What this trial is testingA Longitudinal Study in Parkinson's Disease (PD) PatientsWho this might be right forParkinson's Disease Tel-Aviv Sourasky Medical Center 200
Not applicableUnknownNCT02319382What this trial is testingMeasure of Microglial Activation in the Brain of Parkinson Disease Patients With PETWho this might be right forParkinson's Disease With LRRK2 MutationHealthy ControlsParkinson's Disease Without LRRK2 Mutation Assistance Publique - Hôpitaux de Paris 46
Not applicableUnknownNCT04214509What this trial is testingLIPAD - LRRK2 International Parkinson's Disease StudyWho this might be right forParkinson's Disease and Parkinsonism University of Luebeck 4,000
Early research (Phase 1)Study completedNCT04056689What this trial is testingStudy to Evaluate DNL151 in Subjects With Parkinson's DiseaseWho this might be right forParkinson's Disease Biogen 36
Not applicableStudy completedNCT03545425What this trial is testingFox BioNet Project: LRRK2-002Who this might be right forParkinson Disease Michael J. Fox Foundation for Parkinson's Research 114
Not applicableStudy completedNCT03866603What this trial is testingRostock International Parkinson's Disease Study (ROPAD)Who this might be right forParkinson´s Disease CENTOGENE GmbH Rostock 20,112
Not applicableStudy completedNCT01085227What this trial is testingClinical, Molecular and by Neuroimaging of LRRK2 MutationsWho this might be right forParkinson's Disease Institut National de la Santé Et de la Recherche Médicale, France 50
Not applicableNot Yet RecruitingNCT07681219What this trial is testingLRRK2 (Leucine-Rich Repeat Kinase 2) Parkinson's Disease FingerprintWho this might be right forParkinsons Disease (PD)LRRK2 Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20
Very early researchStudy completedNCT05837130What this trial is testingNon-drug Treatment Study in Parkinson's Disease Patients and Healthy Volunteers to Collect Biological Samples in Order to Assess ex Vivo the Activity of Candidate Therapies and Develop Novel Analytical Methods for BiomarkersWho this might be right forParkinson Disease Servier 45
Not applicableStudy completedNCT03775447What this trial is testingFox BioNet Project: ECV-003Who this might be right forParkinson Disease Michael J. Fox Foundation for Parkinson's Research 38
Not applicableStudy completedNCT04668898What this trial is testingLRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's DiseaseWho this might be right forParkinson DiseaseLRRK2GBA Gene Mutation Icahn School of Medicine at Mount Sinai 203
Not applicableStudy completedNCT04349865What this trial is testingLRRK2 Activity and Markers of Parkinson's Disease in G2385R CarriersWho this might be right forParkinson Disease Xuanwu Hospital, Beijing 211
Not applicableStudy completedNCT05287620What this trial is testingObjective, Passive Assessment of LRRK2 CarriersWho this might be right forParkinson Disease University of Rochester 10
Not applicableStudy completedNCT03782753What this trial is testingMolecular Pathology and Neuronal Networks in LRRK2 Parkinson's DiseaseWho this might be right forParkinson Disease, PARK8Parkinson DiseaseIdiopathic Parkinson Disease King's College London 59
Not applicableUnknownNCT04436848What this trial is testingLRRK2 G2385R Leucocyte and Urine Biomarker StudyWho this might be right forParkinson Disease University of Malaya 150
Large-scale testing (Phase 3)Ended earlyNCT05418673What this trial is testingAssess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating ScaleWho this might be right forParkinson Disease Biogen 7
Testing effectiveness (Phase 2)Looking for participantsNCT07020026What this trial is testingEvaluation of Tau-Pathology in Sporadic and LRRK2 Parkinson's DiseaseWho this might be right forParkinson's Disease Michael J. Fox Foundation for Parkinson's Research 60