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Results for “Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
Not applicableNot Yet RecruitingNCT07075887
What this trial is testing

Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

Who this might be right for
Neuro-OphthalmologyOptic NeuropathiesOptic Atrophy, Hereditary, Leber+3 more
Barboni 70
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Testing effectiveness (Phase 2)Study completedNCT00747487
What this trial is testing

Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 85
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Testing effectiveness (Phase 2)Study completedNCT03140969
What this trial is testing

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

Who this might be right for
Leber's Congenital Amaurosis
Laboratoires Thea 11
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableNo Longer AvailableNCT03672968
What this trial is testing

EAP_GS010_single Patient

Who this might be right for
Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
GenSight Biologics
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Not applicableEnded earlyNCT02982499
What this trial is testing

Biomechanics of Optic Neuropathy

Who this might be right for
Optic Neuropathy
University of Miami 10
Large-scale testing (Phase 3)Study completedNCT00528151
What this trial is testing

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Optic Atrophy, Hereditary, Leber
Mahidol University 70
Not applicableStudy completedNCT02771379
What this trial is testing

Post Authorisation Safety Study With Raxone in LHON Patients

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 229
Testing effectiveness (Phase 2)UnknownNCT02176733
What this trial is testing

Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
University Hospital, Angers 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT05293626
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 12
Large-scale testing (Phase 3)UnknownNCT03153293
What this trial is testing

A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
Huazhong University of Science and Technology 159
Not applicableStudy completedNCT01421381
What this trial is testing

RHODOS Follow-up Single-visit Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 60
Post-approval studies (Phase 4)Study completedNCT02774005
What this trial is testing

Study to Assess the Efficacy and Safety of Raxone in LHON Patients

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 199
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