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Results for “Letermovir”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)Looking for participantsNCT06066957
What this trial is testing

Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

Who this might be right for
Cytomegalovirus InfectionsTransplant-Related Disorder
University of Pennsylvania 80
Not applicableUnknownNCT06339892
What this trial is testing

HCMV Breakthrough Infections During Letermovir Prophylaxis

Who this might be right for
Cytomegalovirus InfectionsCytomegalovirus ViremiaHematopoietic Stem Cell Transplantation
Fondazione IRCCS Policlinico San Matteo di Pavia 140
Large-scale testing (Phase 3)Looking for participantsNCT06334497
What this trial is testing

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections

Who this might be right for
Cytomegalovirus Infection
Assistance Publique - Hôpitaux de Paris 80
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06626555
What this trial is testing

Clinical Trial to Evaluate the Effects of Letermovir Prophylaxis on T-cell Immune Activation in Participants With Treated HIV-1 Infection

Who this might be right for
HIV
University College, London 36
Testing effectiveness (Phase 2)Ended earlyNCT04840199
What this trial is testing

Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.

Who this might be right for
HIV InfectionsCytomegalovirusCMV
National Institute of Allergy and Infectious Diseases (NIAID) 44
Large-scale testing (Phase 3)UnknownNCT06341686
What this trial is testing

Evaluation of the Prophylactic Use of Letermovir in Kidney Transplant Recipients at Risk of Cytomegalovirus Infection

Who this might be right for
CMV Infection
Hospital do Rim e Hipertensão 100
Not applicableLooking for participantsNCT06639854
What this trial is testing

The Use of Cytomegalovirus Cell Mediated Immunity to Optimize the Duration of Letermovir Prophylaxis in Hematopoietic Cell Transplant Recipients

Who this might be right for
Cytomegalovirus Cell Mediated ImmunityHematopoietic Cell Transplant
M.D. Anderson Cancer Center 105
Large-scale testing (Phase 3)Study completedNCT04129398
What this trial is testing

MK-8228 (Letermovir) in the Prevention of Human Cytomegalovirus (CMV) Infection and Disease in Adult Japanese Kidney Transplant Recipients (MK-8228-042)

Who this might be right for
Cytomegalovirus InfectionCytomegalovirus Disease
Merck Sharp & Dohme LLC 22
Testing effectiveness (Phase 2)Looking for participantsNCT06575374
What this trial is testing

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Who this might be right for
Cell Therapy
M.D. Anderson Cancer Center 36
Post-approval studies (Phase 4)Not Yet RecruitingNCT07571135
What this trial is testing

Letermovir vs Valganciclovir in CMV R+ Kidney Transplant

Who this might be right for
CMV InfectionCMVCMV Viremia+1 more
Elisabeth Kincaide 300
Testing effectiveness (Phase 2)Study completedNCT04312841
What this trial is testing

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Who this might be right for
B-Cell Prolymphocytic LeukemiaChronic Lymphocytic LeukemiaPeripheral T-Cell Lymphoma+3 more
Ohio State University Comprehensive Cancer Center 6
Not applicableNot Yet RecruitingNCT06814301
What this trial is testing

Impact of CMV-Specific Immune Reconstitution at the End of Letermovir Prophylaxis on the Development of Late Cytomegalovirus Infection in Hematopoietic Stem Cell Transplant Recipients (INMUNOEND)

Who this might be right for
Cytomegalovirus Cell Mediated ImmunityStem Cell Transplantation, Hematopoietic
Maimónides Biomedical Research Institute of Córdoba 123
Post-approval studies (Phase 4)UnknownNCT05914675
What this trial is testing

Letermovir for Primary Prophylaxis of Cytomegalovirus Infection After R+HID-HSCT

Who this might be right for
The Incidence of Peripheral Blood CMV Activation and Confirmed Clinically Significant CMV Infection Within 24 Weeks After Transplantation
Institute of Hematology & Blood Diseases Hospital, China 21
Early research (Phase 1)Not Yet RecruitingNCT07101055
What this trial is testing

Pharmacokinetics of Oral Letermovir in Adults With End-Stage Kidney Disease With or Without Haemodialysis

Who this might be right for
End-Stage Kidney Disease (ESKD)
Jason A Roberts 20
Large-scale testing (Phase 3)Study completedNCT05763823
What this trial is testing

Letermovir (MK-8228) to Evaluate Efficacy and Safety for Prevention of Cytomegalovirus Infection in Chinese Hematopoietic Stem Cell Transplant Recipients (MK-8228-045)

Who this might be right for
Cytomegalovirus Infection
Merck Sharp & Dohme LLC 120
Not applicableLooking for participantsNCT07488728
What this trial is testing

Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative Disease and Refractory/Relapsed EBV-Associated Hemophagocytic Lymphohistiocytosis

Who this might be right for
EBV-associated T/NK-cell Lymphoproliferative DiseasesRefractory/Relapsed EBV-related Hemophagocytic LymphohistiocytosisLetermovir
Beijing Children's Hospital 80
Not applicableStudy completedNCT04732260
What this trial is testing

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - CYMEVALIII STEP1

Who this might be right for
Pregnant Women Undergoing TOPTOP - Failed Attempted Termination of Pregnancy
Assistance Publique - Hôpitaux de Paris 7
Large-scale testing (Phase 3)Active Not RecruitingNCT06001320
What this trial is testing

De-novo Initiation of Letermovir vs Valganciclovir for Cytomegalovirus Prophylaxis in AA Kidney Transplant Recipients

Who this might be right for
Kidney Transplant; ComplicationsCMV
Virginia Commonwealth University 30
Post-approval studies (Phase 4)Looking for participantsNCT07569653
What this trial is testing

Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT.

Who this might be right for
Cytomegalovirus InfectionsCytomegalovirus DiseaseHematopoietic Stem Cell Transplantation+1 more
WeiShi 120
Large-scale testing (Phase 3)Looking for participantsNCT05446571
What this trial is testing

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Versus Valaciclovir

Who this might be right for
Pregnant WomenCMV Infected Fetuses
Assistance Publique - Hôpitaux de Paris 46
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