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Results for “Letermovir”

48 trials

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Showing 20 of 48 results

Early research (Phase 1)Looking for participantsNCT07199465
What this trial is testing

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

Who this might be right for
Cytomegalovirus Prophylaxis
Merck Sharp & Dohme LLC 40
Testing effectiveness (Phase 2)Looking for participantsNCT06575374
What this trial is testing

Single Arm Pilot Trial of Letermovir for CMV Prophy in CAR T Cell

Who this might be right for
Cell Therapy
M.D. Anderson Cancer Center 36
Testing effectiveness (Phase 2)Study completedNCT04312841
What this trial is testing

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Who this might be right for
B-Cell Prolymphocytic LeukemiaChronic Lymphocytic LeukemiaPeripheral T-Cell Lymphoma+3 more
Ohio State University Comprehensive Cancer Center 6
Large-scale testing (Phase 3)Looking for participantsNCT06334497
What this trial is testing

Letermovir-based Dual Therapy for Treatment of Cytomegalovirus Infections

Who this might be right for
Cytomegalovirus Infection
Assistance Publique - Hôpitaux de Paris 80
Testing effectiveness (Phase 2)Ended earlyNCT04840199
What this trial is testing

Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.

Who this might be right for
HIV InfectionsCytomegalovirusCMV
National Institute of Allergy and Infectious Diseases (NIAID) 44
Large-scale testing (Phase 3)Study completedNCT02137772
What this trial is testing

Letermovir (MK-8228) Versus Placebo in the Prevention of Clinically-Significant Cytomegalovirus (CMV) Infection in Adult, CMV-Seropositive Allogeneic Hematopoietic Stem Cell Transplant Recipients (MK-8228-001)

Who this might be right for
Prevention of CMV Infection or Disease
Merck Sharp & Dohme LLC 570
Not applicableLooking for participantsNCT07488728
What this trial is testing

Letermovir Prophylaxis in Children With EBV-Positive T/NK-Cell Lymphoproliferative Disease and Refractory/Relapsed EBV-Associated Hemophagocytic Lymphohistiocytosis

Who this might be right for
EBV-associated T/NK-cell Lymphoproliferative DiseasesRefractory/Relapsed EBV-related Hemophagocytic LymphohistiocytosisLetermovir
Beijing Children's Hospital 80
Testing effectiveness (Phase 2)Looking for participantsNCT06920251
What this trial is testing

Phase II Trials of Letermovir Prophylaxis in Patients With RRMM Undergoing Elranatamab Therapy

Who this might be right for
Relapsed Refractory Multiple Myeloma (RRMM)
Seoul National University Hospital 40
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06626555
What this trial is testing

Clinical Trial to Evaluate the Effects of Letermovir Prophylaxis on T-cell Immune Activation in Participants With Treated HIV-1 Infection

Who this might be right for
HIV
University College, London 36
Post-approval studies (Phase 4)Study completedNCT04904614
What this trial is testing

Letermovir Use in Heart Transplant Recipients

Who this might be right for
Cytomegalovirus DiseaseCytomegalovirus InfectionsHeart Transplant Infection+2 more
Tufts Medical Center 32
Testing effectiveness (Phase 2)Looking for participantsNCT05432778
What this trial is testing

Cytomegalovirus Prophylaxis With Letermovir in Heart Transplant Recipients

Who this might be right for
CMV Viremia
University Medical Centre Ljubljana 90
Not applicableStudy completedNCT04732260
What this trial is testing

Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - CYMEVALIII STEP1

Who this might be right for
Pregnant Women Undergoing TOPTOP - Failed Attempted Termination of Pregnancy
Assistance Publique - Hôpitaux de Paris 7
Testing effectiveness (Phase 2)Study completedNCT03728426
What this trial is testing

Letermovir Treatment for Refractory or Resistant Cytomegalovirus Infection

Who this might be right for
Cytomegalovirus Infections
Amy C. Sherman, MD 10
Testing effectiveness (Phase 2)Study completedNCT03940586
What this trial is testing

Letermovir Treatment in Pediatric Participants Following Allogeneic Haematopoietic Stem Cell Transplantation (HSCT) (MK-8228-030)

Who this might be right for
Cytomegalovirus (CMV) Infection
Merck Sharp & Dohme LLC 65
Early research (Phase 1)Looking for participantsNCT06118515
What this trial is testing

A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus

Who this might be right for
Congenital Cytomegalovirus Infection
National Institute of Allergy and Infectious Diseases (NIAID) 12
Large-scale testing (Phase 3)Looking for participantsNCT07079735
What this trial is testing

Valganciclovir vs. Letermovir for CMV Prophylaxis in Heart Transplant

Who this might be right for
CMV ViremiaHeart Transplant InfectionHeart Transplant Failure and Rejection
Columbia University 150
Not applicableNot Yet RecruitingNCT06814301
What this trial is testing

Impact of CMV-Specific Immune Reconstitution at the End of Letermovir Prophylaxis on the Development of Late Cytomegalovirus Infection in Hematopoietic Stem Cell Transplant Recipients (INMUNOEND)

Who this might be right for
Cytomegalovirus Cell Mediated ImmunityStem Cell Transplantation, Hematopoietic
Maimónides Biomedical Research Institute of Córdoba 123
Not applicableUnknownNCT06339892
What this trial is testing

HCMV Breakthrough Infections During Letermovir Prophylaxis

Who this might be right for
Cytomegalovirus InfectionsCytomegalovirus ViremiaHematopoietic Stem Cell Transplantation
Fondazione IRCCS Policlinico San Matteo di Pavia 140
Not applicableLooking for participantsNCT06812598
What this trial is testing

Efficacy of Extended Letermovir Prophylaxis to Prevent CMV Reactivation in High-Risk Chinese Adults Undergoing Allogeneic HSCT

Who this might be right for
Cytomegalovirus InfectionsCMV
The First Affiliated Hospital of Soochow University 330
Large-scale testing (Phase 3)Looking for participantsNCT06407232
What this trial is testing

Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients

Who this might be right for
Cytomegalovirus InfectionsKidney Transplant InfectionPancreas Transplant
University of Wisconsin, Madison 90
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