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Results for “Leukoencephalopathies”

421 trials

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Showing 20 of 421 results

Not applicableUnknownNCT04330222
What this trial is testing

Cambridge 7 Tesla Cerebral Small Vessel Disease Study

Who this might be right for
Cerebral Small Vessel DiseasesCerebral Small Vessel Ischemic DiseaseLacunar Stroke
University of Cambridge 210
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Early research (Phase 1)Looking for participantsNCT06150716
What this trial is testing

Orbit Study: A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Intrathecally Administered ION356 in Participants With Pelizaeus Merzbacher Disease (PMD)

Who this might be right for
Pelizaeus-Merzbacher Disease
Ionis Pharmaceuticals, Inc. 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT05893225
What this trial is testing

Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

Who this might be right for
Multiple SclerosisPrimary Progressive Multiple SclerosisSecondary-progressive Multiple Sclerosis
University Hospital, Antwerp 120
Not applicableLooking for participantsNCT06796920
What this trial is testing

Epidural Spinal Cord Stimulation for Lower-limb Impairment in Adrenomyeloneuropathy

Who this might be right for
Adrenomyeloneuropathy Without Cerebral Involvement
Third Military Medical University 10
Not applicableStudy completedNCT05516342
What this trial is testing

LEAD IT! An App to Enable Persons With Early Stage Dementia to Lead Group Activities for Their Peers

Who this might be right for
Dementia, VascularAlzheimer DiseaseDementia, Mixed
Hopeful Aging 182
Not applicableStudy completedNCT01370954
What this trial is testing

NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)

Who this might be right for
Early Memory LossMild Cognitive ImpairmentAlzheimer's Disease+1 more
Pamlab, Inc. 204
Not applicableUnknownNCT01126775
What this trial is testing

Neuro-Prävention im Rahmen Des Interventionsprojektes INVADE-2 (Follow-up Studie)

Who this might be right for
StrokeDementia
INVADE gGmbH 1,000
Not applicableStudy completedNCT02669394
What this trial is testing

Reshaping the Path of Vascular Cognitive Impairment (VCI)

Who this might be right for
Transient Ischemic AttackVascular Cognitive ImpairmentSubcortical Vascular Dementia
University of British Columbia 91
Not applicableWithdrawnNCT01093105
What this trial is testing

An Observational Study of Pediatric Subjects With Globoid Cell Leukodystrophy (GLD)

Who this might be right for
Leukodystrophy, Globoid Cell
Shire
Testing effectiveness (Phase 2)WithdrawnNCT02715505
What this trial is testing

Safety and Exploratory Efficacy of HSC835 in Patients With Inherited Metabolic Disorders (IMD)

Who this might be right for
Inherited Metabolic Disorders IMD
Novartis Pharmaceuticals
Not applicableEnded earlyNCT02204904
What this trial is testing

Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD)

Who this might be right for
X-Linked Adrenoleukodystrophy (X-ALD)Cerebral Adrenoleukodystrophy (CALD)Adrenoleukodystrophy (ALD)
Genetix Biotherapeutics Inc. 59
Testing effectiveness (Phase 2)UnknownNCT05541549
What this trial is testing

Study Evaluating JCPyV-specific T Cell Therapy for PML

Who this might be right for
Progressive Multifocal Leukoencephalopathy
Cellevolve Bio Inc 60
Not applicableUnknownNCT00005900
What this trial is testing

Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Who this might be right for
I Cell DiseaseFucosidosisGloboid Cell Leukodystrophy+9 more
Fairview University Medical Center 10
Not applicableUnknownNCT01951612
What this trial is testing

Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors

Who this might be right for
Ischemic White Matter DiseaseTransient Ischemic AttackMild Stroke+1 more
Baycrest 40
Testing effectiveness (Phase 2)Study completedNCT01056471
What this trial is testing

Autologous Mesenchymal Stem Cells From Adipose Tissue in Patients With Secondary Progressive Multiple Sclerosis

Who this might be right for
Autoimmune DiseasesImmune System DiseasesDemyelinating Diseases+3 more
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud 30
Not applicableLooking for participantsNCT03333200
What this trial is testing

Longitudinal Study of Neurodegenerative Disorders

Who this might be right for
MLDKrabbe DiseaseALD+24 more
University of Pittsburgh 1,500
Large-scale testing (Phase 3)Study completedNCT02453932
What this trial is testing

Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia

Who this might be right for
Vascular Dementia
Dongzhimen Hospital, Beijing 543
Not applicableUnknownNCT03631069
What this trial is testing

Detecting Dementia in the Retina Using Optical Coherence Tomography

Who this might be right for
Dementia AlzheimersDementiaDementia, Vascular+1 more
Moorfields Eye Hospital NHS Foundation Trust 280,000
Not applicableLooking for participantsNCT06120361
What this trial is testing

The Swedish BioFINDER - Primary Care Study

Who this might be right for
Mild DementiaMild Cognitive ImpairmentSCD+4 more
Skane University Hospital 1,200
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