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Results for “MSI-H Advanced Colorectal Cancer”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT03436563
What this trial is testing

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Who this might be right for
Colon AdenocarcinomaHigh-Frequency Microsatellite InstabilityMetastatic Malignant Solid Neoplasm+8 more
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)Looking for participantsNCT06903858
What this trial is testing

Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability HighMismatch Repair Deficiency
Sun Yat-sen University 105
Testing effectiveness (Phase 2)UnknownNCT04301557
What this trial is testing

PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
DMMR Colorectal CancerMSI-H Colorectal CancerLocally Advanced Colorectal Cancer
Sun Yat-sen University 25
Testing effectiveness (Phase 2)Looking for participantsNCT06948448
What this trial is testing

Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Ono Pharmaceutical Co., Ltd. 144
Early research (Phase 1)Ended earlyNCT04244552
What this trial is testing

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Who this might be right for
Breast CancerColorectal CancerOvarian Cancer+13 more
Atreca, Inc. 87
Early research (Phase 1)Study completedNCT04440943
What this trial is testing

The PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Who this might be right for
Non-small Cell Lung CancerBreast CancerGastric Cancer+11 more
Celldex Therapeutics 27
Early research (Phase 1)Ended earlyNCT04234113
What this trial is testing

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Thyroid CancerRenal Cell CarcinomaNon Small Cell Lung Cancer+16 more
SOTIO Biotech AG 115
Testing effectiveness (Phase 2)UnknownNCT05815290
What this trial is testing

Cadonilimab in Locally Advanced MSI-H/dMMR Colorectal Cancer

Who this might be right for
dMMR Colorectal Cancer
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 50
Testing effectiveness (Phase 2)Ended earlyNCT04258111
What this trial is testing

IBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Innovent Biologics (Suzhou) Co. Ltd. 4
Early research (Phase 1)Active Not RecruitingNCT05838768
What this trial is testing

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Who this might be right for
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Novartis Pharmaceuticals 123
Testing effectiveness (Phase 2)Active Not RecruitingNCT04751370
What this trial is testing

Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal AdenocarcinomaStage II Rectal Cancer AJCC v8Stage III Rectal Cancer AJCC v8
National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
Testing effectiveness (Phase 2)UnknownNCT05035381
What this trial is testing

PD-1 Inhibitor Combined With Bevacizumab and FOLFIRI Regimen in the Second-line Treatment of Advanced Colorectal Cancer

Who this might be right for
MSI-H Advanced Colorectal Cancer
Tianjin Medical University Cancer Institute and Hospital 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06423937
What this trial is testing

Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Fudan University 129
Not applicableLooking for participantsNCT06477991
What this trial is testing

The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial.

Who this might be right for
Clinical Complete Response Rate With Negative MRD
Yunnan Cancer Hospital 22
Testing effectiveness (Phase 2)Looking for participantsNCT06002789
What this trial is testing

Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC

Who this might be right for
Multiple CancerColorectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 17
Early research (Phase 1)Looking for participantsNCT06974110
What this trial is testing

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorEndometrial Cancer+4 more
MOMA Therapeutics 132
Testing effectiveness (Phase 2)Active Not RecruitingNCT07523763
What this trial is testing

Neoadjuvant Low-dose Immunotherapy in Locally Advanced MMR-deficient Colorectal Cancer

Who this might be right for
Colorectal Cancer (MSI-H)Colorectal Cancer (CRC)
Blokhin's Russian Cancer Research Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT03926338
What this trial is testing

Neoadjuvant Toripalimab With or Without Celecoxib in dMMR/MSI-H Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
Sun Yat-sen University 270
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