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Results for “MSI-high Colorectal Cancer”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT02997228
What this trial is testing

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage IV Colorectal Cancer AJCC v7
National Cancer Institute (NCI) 120
Early research (Phase 1)Active Not RecruitingNCT05544929
What this trial is testing

Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers

Who this might be right for
Carcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more
Novartis Pharmaceuticals 126
Testing effectiveness (Phase 2)UnknownNCT05913570
What this trial is testing

Cadonilimab as Neoadjuvant Therapy in Resectable Stage II-III MSI-H/dMMR Colorectal Cancer

Who this might be right for
Colorectal CancerMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)+1 more
LiuYing 22
Testing effectiveness (Phase 2)Study completedNCT03436563
What this trial is testing

M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability

Who this might be right for
Colon AdenocarcinomaHigh-Frequency Microsatellite InstabilityMetastatic Malignant Solid Neoplasm+8 more
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Testing effectiveness (Phase 2)Looking for participantsNCT06903858
What this trial is testing

Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerMicrosatellite Instability HighMismatch Repair Deficiency
Sun Yat-sen University 105
Early research (Phase 1)Study completedNCT03871959
What this trial is testing

Pembrolizumab In Combination With Debio 1143 In Pancreatic and Colorectal Advanced/Metastatic Adenocarcinoma

Who this might be right for
Adenocarcinoma of the PancreasAdenocarcinoma of the ColonAdenocarcinoma of the Rectum
Centre Leon Berard 54
Testing effectiveness (Phase 2)Ended earlyNCT06692959
What this trial is testing

A Phase II Trial of Neoadjuvant PD-1 Vaccine PD1-Vaxx in Operable MSI High Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Southampton 3
Early research (Phase 1)Ended earlyNCT02952989
What this trial is testing

A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungCarcinoma, Renal CellBreast Neoplasms+5 more
Seagen Inc. 47
Not applicableStudy completedNCT03495674
What this trial is testing

Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome

Who this might be right for
High-Frequency Microsatellite InstabilityMismatch Repair Gene MutationMutation-Negative Lynch Syndrome+1 more
M.D. Anderson Cancer Center 21
Early research (Phase 1)Ended earlyNCT04234113
What this trial is testing

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Who this might be right for
Thyroid CancerRenal Cell CarcinomaNon Small Cell Lung Cancer+16 more
SOTIO Biotech AG 115
Testing effectiveness (Phase 2)Active Not RecruitingNCT06710847
What this trial is testing

Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalSolid TumorColon Cancer+2 more
GlaxoSmithKline 14
Large-scale testing (Phase 3)Active Not RecruitingNCT05652894
What this trial is testing

HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Taizhou Hanzhong biomedical co. LTD 190
Testing effectiveness (Phase 2)Ended earlyNCT04258111
What this trial is testing

IBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Innovent Biologics (Suzhou) Co. Ltd. 4
Large-scale testing (Phase 3)Looking for participantsNCT06686576
What this trial is testing

Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

Who this might be right for
Colon Cancer
Qilu Pharmaceutical Co., Ltd. 363
Early research (Phase 1)Active Not RecruitingNCT05838768
What this trial is testing

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

Who this might be right for
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Novartis Pharmaceuticals 123
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06646445
What this trial is testing

Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.

Who this might be right for
Colon Cancer
GERCOR - Multidisciplinary Oncology Cooperative Group 60
Testing effectiveness (Phase 2)Looking for participantsNCT07213609
What this trial is testing

Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

Who this might be right for
Neoplasms, ColorectalNeoplasms
GlaxoSmithKline 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07807800
What this trial is testing

DES-1357 in People With Deficient Mismatch Repair (dMMR)/Microsatellite Instability-High (MSI-H) Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal Cancer (CRC)
D. E. Shaw Research, LLC 88
Early research (Phase 1)Study completedNCT02635672
What this trial is testing

Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer

Who this might be right for
Neoplasms
Vincerx Pharma, Inc. 110
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