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Results for “MTOR Inhibitors”

607 trials

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Showing 20 of 607 results

Very early researchStudy completedNCT01184885
What this trial is testing

A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

Who this might be right for
Lymphoid Malignancies (New or Relapsed)Acute Lymphoblastic LeukemiaBurkitt Lymphoma+3 more
Sidney Kimmel Cancer Center at Thomas Jefferson University 7
Not applicableStudy completedNCT02062944
What this trial is testing

SRL (Sirolimus) Withdrawal

Who this might be right for
Acute Rejection of Liver TransplantEffects of Immunosuppressant Therapy
Northwestern University 21
Testing effectiveness (Phase 2)Study completedNCT00827684
What this trial is testing

Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

Who this might be right for
Metastatic Colorectal Cancer
Vejle Hospital 50
Early research (Phase 1)Ended earlyNCT01378377
What this trial is testing

Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus

Who this might be right for
Advanced Solid Tumor
EMD Serono 33
Testing effectiveness (Phase 2)Study completedNCT01412892
What this trial is testing

Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaNeurofibromatoses
Assistance Publique - Hôpitaux de Paris 30
Post-approval studies (Phase 4)Study completedNCT01601821
What this trial is testing

Open Label Comparative Study Of De Novo Renal Allograft Recipients Receiving CSA + MMF + Corticosteroids Versus CSA + Rapamune + Corticosteroids

Who this might be right for
Inflammation
Pfizer 245
Early research (Phase 1)Study completedNCT02048384
What this trial is testing

Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22
Testing effectiveness (Phase 2)WithdrawnNCT01851408
What this trial is testing

Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

Who this might be right for
MelanomaRecurrent MelanomaStage III Melanoma+1 more
National Cancer Institute (NCI)
Early research (Phase 1)Study completedNCT00525889
What this trial is testing

Proleukin and Rapamune in Type 1 Diabetes

Who this might be right for
Diabetes Mellitus, Type 1
National Institute of Allergy and Infectious Diseases (NIAID) 9
Testing effectiveness (Phase 2)Study completedNCT02080624
What this trial is testing

Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome

Who this might be right for
Sturge- Weber Syndrome
Clinica Universidad de Navarra, Universidad de Navarra 23
Early research (Phase 1)Study completedNCT01649960
What this trial is testing

Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial

Who this might be right for
AgingCAD
Mayo Clinic 13
Early research (Phase 1)Study completedNCT00593060
What this trial is testing

Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Adenocarcinoma
Jeffrey W. Clark, MD 35
Testing effectiveness (Phase 2)Study completedNCT00411788
What this trial is testing

A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Yale University 11
Large-scale testing (Phase 3)Study completedNCT00789828
What this trial is testing

Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)

Who this might be right for
Tuberous SclerosisSubependymal Giant Cell Astrocytoma
Novartis Pharmaceuticals 117
Early research (Phase 1)Study completedNCT00349206
What this trial is testing

Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

Who this might be right for
MelanomaRecurrent MelanomaStage III Melanoma+1 more
National Cancer Institute (NCI) 69
Not applicableStudy completedNCT01210482
What this trial is testing

Temsirolimus (Torisel) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)

Who this might be right for
Renal Cell Carcinoma
Pfizer 1,050
Large-scale testing (Phase 3)Active Not RecruitingNCT04582136
What this trial is testing

Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
Chinese SLE Treatment And Research Group 146
Early research (Phase 1)Study completedNCT01548807
What this trial is testing

Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy

Who this might be right for
Prostate Cancer Patients With Detectable PSA Following Prostatectomy
Abramson Cancer Center at Penn Medicine 19
Early research (Phase 1)Study completedNCT00784914
What this trial is testing

A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors

Who this might be right for
Brain and Central Nervous System TumorsMetastatic Cancer
City of Hope Medical Center 12
Post-approval studies (Phase 4)Looking for participantsNCT06722586
What this trial is testing

Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia

Who this might be right for
Antiphospholipid (aPL)-PositiveThrombocytopaenia
Peking University First Hospital 84
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