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Results for “Metastatic Malignant Neoplasm to the Leptomeninges”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT05805631
What this trial is testing

Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungEpidermal Growth Factor ReceptorLeptomeningeal Metastasis
Taipei Veterans General Hospital, Taiwan 23
Testing effectiveness (Phase 2)Study completedNCT01325207
What this trial is testing

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

Who this might be right for
Breast Cancer
Northwestern University 34
Early research (Phase 1)Active Not RecruitingNCT03696030
What this trial is testing

HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases

Who this might be right for
Malignant NeoplasmMetastatic Malignant Neoplasm in the BrainMetastatic Malignant Neoplasm in the Leptomeninges+2 more
City of Hope Medical Center 24
Post-approval studies (Phase 4)Looking for participantsNCT07092202
What this trial is testing

Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases

Who this might be right for
Leptomeningeal MetastasisNSCLCIntrathecal Chemotherapy+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 40
Testing effectiveness (Phase 2)UnknownNCT04833205
What this trial is testing

Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer

Who this might be right for
Leptomeningeal MetastasisLung Cancer
Hui Bu 30
Testing effectiveness (Phase 2)Looking for participantsNCT07559097
What this trial is testing

Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer

Who this might be right for
Leptomeningeal Metastasis From Lung Cancer
Henan Cancer Hospital 14
Early research (Phase 1)Study completedNCT00002750
What this trial is testing

Melphalan in Patients With Neoplastic Meningitis

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorLeukemia+2 more
Duke University 6
Testing effectiveness (Phase 2)Study completedNCT04343573
What this trial is testing

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 102
Testing effectiveness (Phase 2)Looking for participantsNCT05800275
What this trial is testing

Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseHER2-positive Metastatic Breast Cancer
UNICANCER 30
Early research (Phase 1)Active Not RecruitingNCT05598853
What this trial is testing

Intrathecal Double Checkpoint Inhibition

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung Cancer Stage IVMelanoma Stage IV
University of Zurich 26
Early research (Phase 1)Active Not RecruitingNCT05034497
What this trial is testing

Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Cerenome 18
Testing effectiveness (Phase 2)Study completedNCT06812871
What this trial is testing

High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis

Who this might be right for
Non-small Cell Lung Cancer Metastatic
Sun Yat-sen University 46
Testing effectiveness (Phase 2)Looking for participantsNCT06462092
What this trial is testing

Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer

Who this might be right for
Leptomeningeal Metastases
Guangzhou Medical University 34
Testing effectiveness (Phase 2)Study completedNCT04563871
What this trial is testing

Efficacy and Safety of 80mg Osimertinib in Patients With Non-small Cell Lung Cancer(NSCLC)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Sehhoon Park 73
Early research (Phase 1)Ended earlyNCT00074607
What this trial is testing

Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine

Who this might be right for
MeningitisNeoplasms
Baylor College of Medicine 10
Not applicableLooking for participantsNCT06718972
What this trial is testing

A Real-world Study on the Treatment of Non-small Cell Lung Cancer With Leptomeningeal Metastasis in China

Who this might be right for
Meningeal MetastasisNon-Small Cell Lung Cancer
Guangzhou Medical University 1,000
Early research (Phase 1)Study completedNCT00005842
What this trial is testing

Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer

Who this might be right for
Cancer
National Cancer Institute (NCI) 24
Not applicableUnknownNCT04778800
What this trial is testing

A Dose Exploration Study of Almonertinib for EGFRm NSCLC Patients With Brain/Leptomeningeal Metastasis (ARTISTRY)

Who this might be right for
NSCLCBrain MetastasesLeptomeningeal Metastasis
Henan Cancer Hospital 60
Not applicableStudy completedNCT06592092
What this trial is testing

Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3+ Solid Tumors

Who this might be right for
Solid TumorMeningeal Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 3
Not applicableStudy completedNCT04178343
What this trial is testing

Tomotherapy for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Chinese Academy of Medical Sciences 103
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