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Results for “Microsatellite Stable Metastatic Colorectal Cancer”

111 trials

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Showing 20 of 111 results

Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)UnknownNCT04724239
What this trial is testing

Sintilimab and Chidamide in Combination With or Without IBI305 in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma

Who this might be right for
Advanced Microsatellite Stable Colorectal CancerMetastatic Microsatellite-stable Colorectal Cancer
Sun Yat-sen University 48
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Very early researchLooking for participantsNCT07328087
What this trial is testing

COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColorectal Cancer Stage IIIColorectal Cancer Stage IV
Biogenea Pharmaceuticals Ltd. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04068610
What this trial is testing

COLUMBIA-1: Novel Oncology Therapies in Combination With Chemotherapy and Bevacizumab as First- Line Therapy in MSS-CRC

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
MedImmune LLC 61
Early research (Phase 1)Looking for participantsNCT06654037
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Who this might be right for
Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8
National Cancer Institute (NCI) 39
Testing effectiveness (Phase 2)WithdrawnNCT06575725
What this trial is testing

Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer

Who this might be right for
Advanced Colon AdenocarcinomaAdvanced Colorectal AdenocarcinomaAdvanced Rectal Adenocarcinoma+9 more
City of Hope Medical Center
Testing effectiveness (Phase 2)Study completedNCT02060188
What this trial is testing

Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

Who this might be right for
Microsatellite Unstable Colorectal CancerMicrosatellite Stable Colorectal CancerMismatch Repair Proficient Colorectal Cancer+1 more
Bristol-Myers Squibb 385
Testing effectiveness (Phase 2)Looking for participantsNCT05963490
What this trial is testing

Regorafenib Alone or in Combination With Hypofractionated/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer

Who this might be right for
Microsatellite Stable Metastatic Colorectal Cancer
Fudan University 108
Testing effectiveness (Phase 2)Active Not RecruitingNCT06268015
What this trial is testing

Botensilimab and Balstilimab Optimization in Colorectal Cancer

Who this might be right for
Colorectal Cancer
Nicholas DeVito, MD 16
Early research (Phase 1)Ended earlyNCT04060342
What this trial is testing

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic AdenocarcinomaEsophageal AdenocarcinomaEsophageal Squamous Cell Carcinoma+11 more
GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. 61
Testing effectiveness (Phase 2)UnknownNCT04262687
What this trial is testing

Chemotherapy and Immunotherapy as Treatment for MSS Metastatic Colorectal Cancer With High Immune Infiltrate

Who this might be right for
Colorectal Cancer MetastaticHigh Immune InfiltrateMicrosatellite Stable
Federation Francophone de Cancerologie Digestive 55
Not applicableNot Yet RecruitingNCT06682247
What this trial is testing

A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Feng Wang 200
Testing effectiveness (Phase 2)Active Not RecruitingNCT05627635
What this trial is testing

FOLFOX and Bevacizumab in Combination With Botensilimab and Balstilimab (3B-FOLFOX) for the Treatment of Microsatellite Stable (MSS) Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colon AdenocarcinomaMetastatic Colorectal AdenocarcinomaMetastatic Microsatellite Stable Colorectal Carcinoma+4 more
City of Hope Medical Center 20
Testing effectiveness (Phase 2)Ended earlyNCT03791398
What this trial is testing

BrUOG 379 Phase Ib/II Trial ONC201 + Nivolumab in MSS mCRC

Who this might be right for
Metastatic Colorectal Cancer
Brown University 13
Testing effectiveness (Phase 2)WithdrawnNCT03576963
What this trial is testing

Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal AdenocarcinomaCpG Island Methylator PhenotypeMetastatic Microsatellite Stable Colorectal Carcinoma+5 more
University of Southern California
Testing effectiveness (Phase 2)Looking for participantsNCT05919264
What this trial is testing

FOG-001 in Locally Advanced or Metastatic Solid Tumors

Who this might be right for
CancerColorectal CancerSolid Tumor+12 more
Parabilis Medicines, Inc. 595
Testing effectiveness (Phase 2)UnknownNCT03608046
What this trial is testing

Avelumab Combined With Cetuximab and Irinotecan for Treatment Refractory Metastatic Colorectal Microsatellite Stable Cancer

Who this might be right for
Colorectal Neoplasms, Malignant
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 59
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