Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Microsatellite-instability-high Solid Tumor”

78 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 78 results

Not applicableNot Yet RecruitingNCT07645742
What this trial is testing

Pilot Study of Intermittent Fasting With Immune Checkpoint Inhibitors

Who this might be right for
Cancer (Advanced Stage)
West Virginia University 90
Testing effectiveness (Phase 2)Looking for participantsNCT03667170
What this trial is testing

KN035 for dMMR/MSI-H Advanced Solid Tumors

Who this might be right for
Solid Tumor
3D Medicines (Sichuan) Co., Ltd. 200
Early research (Phase 1)Study completedNCT04242199
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more
Incyte Corporation 182
Testing effectiveness (Phase 2)WithdrawnNCT04001101
What this trial is testing

Anti-PD-1 +/- RT for MSI-H Solid Tumors

Who this might be right for
Microsatellite Instability HighMismatch Repair DeficiencyColorectal Cancer
University of Colorado, Denver
Not applicableNot Yet RecruitingNCT07274657
What this trial is testing

Superb Microvascular Imaging (SMI) and Two-Dimensional Endoscopic Ultrasound Guided Shear Wave Elastography (2D-SWE-EUS) in Differential Diagnosis of Pancreatic Adenocarcinoma (PA) From Other Pancreatic Solid Lesions (PSLs) and Pancreatic neuroendocrinE Tumors (pNETs) Malignancy

Who this might be right for
Pancreas Adenocarcinoma (MSI-H)Pancreatic Neuroendocrine Tumors (pNET)
GCS Ramsay Santé pour l'Enseignement et la Recherche 150
Testing effectiveness (Phase 2)Looking for participantsNCT04114136
What this trial is testing

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Who this might be right for
MelanomaNSCLCHepatocellular Carcinoma+5 more
Dan Zandberg 72
Early research (Phase 1)Ended earlyNCT05909995
What this trial is testing

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

Who this might be right for
MelanomaHepatocellular Carcinoma (HCC)Renal Cell Carcinoma (RCC)+3 more
Incyte Corporation 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822
What this trial is testing

Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Who this might be right for
Advanced Solid Tumor
Incyte Corporation 73
Early research (Phase 1)Study completedNCT04440943
What this trial is testing

The PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Who this might be right for
Non-small Cell Lung CancerBreast CancerGastric Cancer+11 more
Celldex Therapeutics 27
Testing effectiveness (Phase 2)Looking for participantsNCT02332668
What this trial is testing

Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

Who this might be right for
MelanomaLymphomaSolid Tumor+2 more
Merck Sharp & Dohme LLC 370
Testing effectiveness (Phase 2)WithdrawnNCT06331598
What this trial is testing

Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)

Who this might be right for
Solid Tumors
Hoffmann-La Roche
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07259473
What this trial is testing

Factors Influencing Immunotherapy Response in dMMR/MSI-H Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric / Gastroesophageal Junction AdenocarcinomaMismatch Repair Deficient or MSI-High Solid TumorsImmunotherapy
Shanghai Zhongshan Hospital 15
Testing effectiveness (Phase 2)UnknownNCT03475953
What this trial is testing

A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors

Who this might be right for
Colorectal Cancer Not MSI-H or MMR-deficientGISTOesophageal or Gastric Carcinoma+12 more
Institut Bergonié 747
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Not applicableUnknownNCT06004713
What this trial is testing

Registry Study in MSI/dMMR Solid Tumors

Who this might be right for
DMMR CancerMSI-HSolid Tumor
Peking University Cancer Hospital & Institute 190
Testing effectiveness (Phase 2)Ended earlyNCT05714553
What this trial is testing

NUC-3373 in Combination With Other Agents in Patients With Advanced Solid Tumours

Who this might be right for
Advanced CancerAdvanced Solid TumorNeoplasm Malignant+14 more
NuCana plc 19
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Very early researchEnded earlyNCT03454243
What this trial is testing

Oral Immunomodulatory Tyrosine Kinase Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Hoffmann-La Roche 1
Early research (Phase 1)Looking for participantsNCT06974110
What this trial is testing

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorEndometrial Cancer+4 more
MOMA Therapeutics 132
Testing effectiveness (Phase 2)Looking for participantsNCT06898450
What this trial is testing

Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

Who this might be right for
Advanced Solid Tumors CancerMSI-H Cancer
Nimbus Wadjet, Inc. 134
Load More Results