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Results for “Mild and Moderate Hepatic Impairment”

144 trials

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Showing 20 of 144 results

Early research (Phase 1)Not Yet RecruitingNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT02063230
What this trial is testing

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Who this might be right for
Solid Tumors
AstraZeneca 32
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT02004587
What this trial is testing

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Who this might be right for
Hepatic Impairment
LG Life Sciences 28
Early research (Phase 1)Study completedNCT02259855
What this trial is testing

Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 36
Early research (Phase 1)Study completedNCT06425198
What this trial is testing

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Participants
Bristol-Myers Squibb 37
Early research (Phase 1)Study completedNCT05467722
What this trial is testing

Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543

Who this might be right for
Hepatic Impairment
Concert Pharmaceuticals 21
Early research (Phase 1)Study completedNCT02536911
What this trial is testing

The Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate

Who this might be right for
Gaucher Disease
Genzyme, a Sanofi Company 24
Early research (Phase 1)Study completedNCT02859207
What this trial is testing

Evaluate the Pharmacokinetics of E2609 and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared With Healthy Subjects

Who this might be right for
Early Alzheimer's Disease
Eisai Inc. 32
Early research (Phase 1)Study completedNCT02910739
What this trial is testing

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

Who this might be right for
Amnestic Mild Cognitive ImpairmentAlzheimer's DiseaseProdromal Alzheimer's Disease
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Study completedNCT00437424
What this trial is testing

Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction

Who this might be right for
Carcinoma, Hepatocellular
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT05088642
What this trial is testing

A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects

Who this might be right for
Sever Aplastic Anaemia
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Looking for participantsNCT07401862
What this trial is testing

Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

Who this might be right for
Hepatic Insufficiency
Eli Lilly and Company 36
Early research (Phase 1)Study completedNCT01762462
What this trial is testing

Open Label Pharmacokinetic Study of SAR302503 in Subjects With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Bristol-Myers Squibb 17
Early research (Phase 1)Study completedNCT05409911
What this trial is testing

Assess S-217622 in Participants With Mild and Moderate Hepatic Impairment and Healthy Control Participants

Who this might be right for
Hepatic Impairment
Shionogi 25
Early research (Phase 1)Study completedNCT01197911
What this trial is testing

The Effect of Hepatic Impairment on The Pharmacokinetics of Aleglitazar

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 38
Early research (Phase 1)Study completedNCT01579461
What this trial is testing

Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment Compared to Healthy Subjects

Who this might be right for
PharmacokineticsHealthy SubjectsMild and Moderate Hepatic Impairment
Astellas Pharma Europe B.V. 32
Early research (Phase 1)Ended earlyNCT04332523
What this trial is testing

JNJ-53718678 in Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Janssen Research & Development, LLC 25
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