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Results for “Mitochondrial Encephalomyopathies”

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Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT05972954
What this trial is testing

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)

Who this might be right for
Primary Mitochondrial Disease
Omeicos Therapeutics GmbH 28
Very early researchStudy completedNCT01339494
What this trial is testing

Nitric Oxide Production in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 30
Early research (Phase 1)Study completedNCT02544217
What this trial is testing

A Dose-escalating Clinical Trial With KH176

Who this might be right for
MELASLHONLeigh Syndrome+2 more
Khondrion BV 32
Early research (Phase 1)Study completedNCT03952234
What this trial is testing

L-Citrulline Dose Finding Safety Study in MELAS

Who this might be right for
MELAS Syndrome
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Temporarily pausedNCT04846036
What this trial is testing

The KHENERGYC Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMELAS+1 more
Khondrion BV 24
Not applicableLooking for participantsNCT05848271
What this trial is testing

Natural History Study of Patients with HPDL Mutations

Who this might be right for
Mitochondrial EncephalomyopathiesHereditary Spastic ParaplegiaSpastic Paraplegia+4 more
University of California, San Diego 50
Large-scale testing (Phase 3)Ended earlyNCT04378075
What this trial is testing

Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy

Who this might be right for
Mitochondrial DiseasesDrug Resistant EpilepsyLeigh Disease+5 more
PTC Therapeutics 68
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableLooking for participantsNCT06213090
What this trial is testing

Patterns of Neurodevelopmental Disorders

Who this might be right for
Neurodevelopmental DisordersAutism Spectrum DisorderPediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection+5 more
Richard Frye 1,000
Testing effectiveness (Phase 2)Study completedNCT06644534
What this trial is testing

Assess TTI-0102 vs Placebo in MELAS Patients

Who this might be right for
MELAS SyndromeMitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Thiogenesis Therapeutics, Inc. 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT06961344
What this trial is testing

An Open-label Extension Safety Study of MELAS Patients Who Completed TIS6463-203 (PRIZM)

Who this might be right for
Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Tisento Therapeutics 44
Not applicableNot Yet RecruitingNCT06013397
What this trial is testing

Effectiveness of Ketogenic Diet in MELAS Syndrome

Who this might be right for
MELAS SyndromeKetogenic Dieting
Second Affiliated Hospital, Zhejiang University, School of Medicine 100
Not applicableLooking for participantsNCT01532791
What this trial is testing

Natural History Study - Mitochondrial Disease

Who this might be right for
MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Columbia University 300
Very early researchStudy completedNCT01252979
What this trial is testing

Ketones & Mitochondrial Heteroplasmy

Who this might be right for
MELAS SyndromeMitochondrial Diseases
The University of Texas Health Science Center, Houston 13
Not applicableStudy completedNCT04948138
What this trial is testing

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

Who this might be right for
MELAS Syndrome
Jesús González de la Aleja Tejera 9
Not applicableEnrolling By InvitationNCT01803906
What this trial is testing

Tissue Sample Study for Mitochondrial Disorders

Who this might be right for
Mitochondrial DisordersMitochondrial DiseaseMelas+6 more
Columbia University 6,900
Early research (Phase 1)Looking for participantsNCT05241262
What this trial is testing

Study of N-acetylcysteine in the Treatment of Patients With the m.3243A>G Mutation and Low Brain Glutathione Levels

Who this might be right for
Mitochondrial Disease
Michio Hirano, MD 18
Not applicableStudy completedNCT00004353
What this trial is testing

Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia

Who this might be right for
Mitochondrial MyopathyMELAS SyndromeLactic Acidosis
National Center for Research Resources (NCRR) 35
Large-scale testing (Phase 3)Looking for participantsNCT06451757
What this trial is testing

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Who this might be right for
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV 220
Testing effectiveness (Phase 2)Study completedNCT04604548
What this trial is testing

The KHENEREXT Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMaternally Inherited Diabetes and Deafness (MIDD)+2 more
Khondrion BV 11
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