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Results for “Moderate Hepatic Impairment”

242 trials

Showing 20 of 242 results

Early research (Phase 1)Study completedNCT02536911
What this trial is testing

The Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate

Who this might be right for
Gaucher Disease
Genzyme, a Sanofi Company 24
Early research (Phase 1)Looking for participantsNCT06952634
What this trial is testing

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Who this might be right for
Hepatic Impairment
Alumis Inc 48
Early research (Phase 1)UnknownNCT04631575
What this trial is testing

An Investigational Study of SHR6390 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Who this might be right for
Hepatic ImpairmentHealthy Participants
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT05790304
What this trial is testing

Study to Investigate Hepatic Impairment on PK, Safety, Tolerability of Camizestrant in Post-Menopausal Female Subjects

Who this might be right for
Hepatic Impairment
AstraZeneca 22
Early research (Phase 1)Looking for participantsNCT04617522
What this trial is testing

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Who this might be right for
Advanced or Metastatic Solid TumorLiver Failure
Gilead Sciences 30
Early research (Phase 1)Study completedNCT01027169
What this trial is testing

Assess the Effect of Hepatic Impairment on Safinamide Pharmacokinetics

Who this might be right for
Hepatic Impairment
Newron Pharmaceuticals SPA 24
Early research (Phase 1)Study completedNCT02859207
What this trial is testing

Evaluate the Pharmacokinetics of E2609 and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared With Healthy Subjects

Who this might be right for
Early Alzheimer's Disease
Eisai Inc. 32
Early research (Phase 1)Study completedNCT01762462
What this trial is testing

Open Label Pharmacokinetic Study of SAR302503 in Subjects With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Bristol-Myers Squibb 17
Early research (Phase 1)Looking for participantsNCT06908954
What this trial is testing

The Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Who this might be right for
Hepatic ImpairmentHealthy
Ipsen 32
Early research (Phase 1)Study completedNCT00672581
What this trial is testing

Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
AstraZeneca 32
Not applicableStudy completedNCT05912933
What this trial is testing

Learn About the Relationship Between Hepatic Impairment and Myelosuppression (Decreased Bone Marrow Function) in Breast Cancer Patients Treated With the Study Medicine Palbociclib (Pal-bow-sai-klib)

Who this might be right for
Breast Cancer
Pfizer 733
Early research (Phase 1)Ended earlyNCT04136444
What this trial is testing

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Who this might be right for
Healthy Study ParticipantsImpaired Hepatic Function
UCB Biopharma S.P.R.L. 12
Early research (Phase 1)Study completedNCT02016911
What this trial is testing

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Hepatic Impairment

Who this might be right for
DiabetesDiabetes Mellitus, Type 2Healthy
Novo Nordisk A/S 56
Early research (Phase 1)Study completedNCT02004587
What this trial is testing

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Who this might be right for
Hepatic Impairment
LG Life Sciences 28
Early research (Phase 1)Study completedNCT06568861
What this trial is testing

Evaluate the Pharmacokinetics, Safety and Tolerability of ALG-097558 in Subjects With Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Who this might be right for
COVID-19
Aligos Therapeutics 16
Early research (Phase 1)Looking for participantsNCT07343960
What this trial is testing

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Who this might be right for
Moderate Hepatic Impairment
AstraZeneca 20
Not applicableStudy completedNCT01054586
What this trial is testing

Fosamprenavir in Pts With Hepatic Impairment

Who this might be right for
Infection, Human Immunodeficiency Virus
GlaxoSmithKline 167
Early research (Phase 1)Study completedNCT01319279
What this trial is testing

Evaluate the Pharmacokinetics of the Hydrocodone Extended-Release Tablet (CEP-33237) in Subjects With Normal Hepatic Function and Subjects With Moderate Hepatic Impairment

Who this might be right for
Hepatic Impairment
Cephalon 16
Early research (Phase 1)Study completedNCT05537142
What this trial is testing

Assess the Phamacokinetics of BV100 in Participants with Varying Degrees of Hepatic Impairment

Who this might be right for
Healthy Participants
BioVersys AG 33
Early research (Phase 1)Study completedNCT01571388
What this trial is testing

Compare Pharmacokinetics Of Dacomitinib (PF-00299804) Between Healthy Subjects And Subjects With Mild And Moderate Hepatic Impairment

Who this might be right for
HealthyOtherwise Healthy Volunteers With Mild or Moderate Hepatic Dysfunction
Pfizer 25
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