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Results for “Moderate Hepatic Impairment”

244 trials

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Showing 20 of 244 results

Early research (Phase 1)Not Yet RecruitingNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT02063230
What this trial is testing

To Assess the Pharmacokinetics, Safety and Tolerability of Selumetinib in Patients With Hepatic Impairment and Healthy Subjects

Who this might be right for
Solid Tumors
AstraZeneca 32
Early research (Phase 1)Study completedNCT03521037
What this trial is testing

Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor

Who this might be right for
Neoplasms
pharmaand GmbH 16
Early research (Phase 1)Study completedNCT02286609
What this trial is testing

A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics

Who this might be right for
Hepatic Impairment
PTC Therapeutics 16
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT06535399
What this trial is testing

Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Celgene 29
Early research (Phase 1)Study completedNCT02004587
What this trial is testing

Influence of Hepatic Impairment on Pharmacokinetic (PK) and Pharmacodynamic (PD) of Gemigliptin PK and PD After Multiple Oral Doses in Healthy White Volunteers

Who this might be right for
Hepatic Impairment
LG Life Sciences 28
Early research (Phase 1)Study completedNCT02259855
What this trial is testing

Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 36
Early research (Phase 1)Looking for participantsNCT06442436
What this trial is testing

Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

Who this might be right for
Hepatic Impairment (HI)
Merck Sharp & Dohme LLC 32
Early research (Phase 1)Study completedNCT06425198
What this trial is testing

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Participants
Bristol-Myers Squibb 37
Early research (Phase 1)Study completedNCT05467722
What this trial is testing

Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of CTP-543

Who this might be right for
Hepatic Impairment
Concert Pharmaceuticals 21
Early research (Phase 1)Study completedNCT02536911
What this trial is testing

The Effects of Hepatic Impairment on the Pharmacokinetics and Tolerability of Eliglustat Tartrate

Who this might be right for
Gaucher Disease
Genzyme, a Sanofi Company 24
Early research (Phase 1)Ended earlyNCT05209295
What this trial is testing

Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Who this might be right for
Hepatic InsufficiencyNeoplasms
Bristol-Myers Squibb 2
Early research (Phase 1)Study completedNCT02859207
What this trial is testing

Evaluate the Pharmacokinetics of E2609 and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared With Healthy Subjects

Who this might be right for
Early Alzheimer's Disease
Eisai Inc. 32
Early research (Phase 1)Study completedNCT02910739
What this trial is testing

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

Who this might be right for
Amnestic Mild Cognitive ImpairmentAlzheimer's DiseaseProdromal Alzheimer's Disease
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Study completedNCT03814005
What this trial is testing

Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problems

Who this might be right for
Myelodysplastic SyndromesLeukemia, Myelomonocytic, ChronicLeukemia, Myeloid, Acute+3 more
Takeda 17
Early research (Phase 1)Study completedNCT03802786
What this trial is testing

Pharmacokinetics of Imeglimin in Hepatic Impaired Subjects

Who this might be right for
Hepatic Impairment
Poxel SA 14
Early research (Phase 1)Ended earlyNCT05126329
What this trial is testing

Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 13
Early research (Phase 1)Study completedNCT00437424
What this trial is testing

Brivanib (BMS-582664) in Patients With Liver Cancer and Mild, Moderate or Severe Liver Dysfunction

Who this might be right for
Carcinoma, Hepatocellular
Bristol-Myers Squibb 24
Early research (Phase 1)Study completedNCT05088642
What this trial is testing

A Trial of Hetrombopag in Healthy and Hepatic Impairment Subjects

Who this might be right for
Sever Aplastic Anaemia
Jiangsu HengRui Medicine Co., Ltd. 24
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