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Results for “Moderate Hepatic Impairment”

252 trials

Showing 20 of 252 results

Early research (Phase 1)Study completedNCT07248839
What this trial is testing

Assess the Drug Levels and Safety of BMS-986435 in Participants With Normal Hepatic Function and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Healthy VolunteersHepatic Impairment
Bristol-Myers Squibb 69
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT03890809
What this trial is testing

An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage

Who this might be right for
Liver DysfunctionHealthy Volunteers
Bristol-Myers Squibb 32
Early research (Phase 1)Study completedNCT03713242
What this trial is testing

Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment

Who this might be right for
Hepatic Impairment
Idorsia Pharmaceuticals Ltd. 32
Early research (Phase 1)Looking for participantsNCT07023354
What this trial is testing

Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
HealthyHepatic Impairment
Boehringer Ingelheim 32
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT05560464
What this trial is testing

Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment

Who this might be right for
Pain
Vertex Pharmaceuticals Incorporated 36
Early research (Phase 1)Study completedNCT06425198
What this trial is testing

Study to Assess Drug Levels and Safety of BMS-986278 in Healthy Participants and Participants With Different Degrees of Hepatic Impairment

Who this might be right for
Hepatic ImpairmentHealthy Participants
Bristol-Myers Squibb 37
Early research (Phase 1)Study completedNCT01012284
What this trial is testing

TMC207 in Patients With Moderately Impaired Hepatic Function

Who this might be right for
Moderate Hepatic Impairment
Tibotec BVBA 16
Early research (Phase 1)Study completedNCT00736905
What this trial is testing

TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function.

Who this might be right for
HIVAIDSHepatic Impairment
Tibotec Pharmaceuticals, Ireland 32
Early research (Phase 1)Study completedNCT02161770
What this trial is testing

Study to Assess the Blood Levels and Safety of AZD9291 in Patients With Advanced Solid Tumours and Normal Liver Function or Mild or Moderate Liver Impairment

Who this might be right for
Solid Tumours
AstraZeneca 30
Early research (Phase 1)Study completedNCT05329623
What this trial is testing

Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.

Who this might be right for
Small Cell Lung Carcinoma
Novartis Pharmaceuticals 33
Early research (Phase 1)Study completedNCT06908954
What this trial is testing

The Blood Levels of Palovarotene in Participants With Abnormal Liver Function Compared to Healthy Adult Participants After Intake of a Single Dose

Who this might be right for
Hepatic ImpairmentHealthy
Ipsen 31
Early research (Phase 1)WithdrawnNCT04759846
What this trial is testing

Hepatic Impairment Study of Encorafenib in Combination With Binimetinib in BRAF Melanoma

Who this might be right for
BRAF V600 MutationUnresectable MelanomaMetastatic Melanoma+1 more
Pierre Fabre Medicament
Testing effectiveness (Phase 2)Study completedNCT01830127
What this trial is testing

BI 207127 / Faldaprevir Combination Therapy in Hepatic Impairment (Child-Pugh B) Patients With Genotype 1b Chronic Hepatitis C Infection: HCVerso3

Who this might be right for
Hepatitis C, Chronic
Boehringer Ingelheim 35
Early research (Phase 1)Looking for participantsNCT04953910
What this trial is testing

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndromes
Taiho Oncology, Inc. 27
Early research (Phase 1)Study completedNCT02249442
What this trial is testing

Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency

Who this might be right for
Hepatic Insufficiency
Boehringer Ingelheim 24
Early research (Phase 1)Study completedNCT01764776
What this trial is testing

Effect of Hepatic Impairment on LDE225..

Who this might be right for
Normal Hepatic FunctionImpaired Hepatic Function
Novartis Pharmaceuticals 33
Early research (Phase 1)Study completedNCT03626415
What this trial is testing

A Hepatic Impairment Study for PF-04965842.

Who this might be right for
Hepatic Impairment
Pfizer 24
Early research (Phase 1)WithdrawnNCT03912350
What this trial is testing

The Effect of Hepatic Impairment on the Pharmacokinetics of Balovaptan

Who this might be right for
Autism Spectrum Disorder
Hoffmann-La Roche
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