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Results for “Moderate Hepatic Impairment”

248 trials

Showing 20 of 248 results

Early research (Phase 1)Study completedNCT01185873
What this trial is testing

Danoprevir in Healthy Volunteers And Patients With Hepatic Impairment

Who this might be right for
Healthy Volunteer
Hoffmann-La Roche 81
Early research (Phase 1)Study completedNCT01565902
What this trial is testing

Pharmacokinetics of BAF312 in Patients With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 40
Early research (Phase 1)Study completedNCT06093230
What this trial is testing

A Study in Subjects With Liver Function Injury and Subjects With Normal Liver Function

Who this might be right for
Subjects With Liver Function InjuryNormal Liver Function Subject
Shanghai Vinnerna Biosciences Co., Ltd. 24
Early research (Phase 1)Study completedNCT05537142
What this trial is testing

Assess the Phamacokinetics of BV100 in Participants with Varying Degrees of Hepatic Impairment

Who this might be right for
Healthy Participants
BioVersys AG 33
Early research (Phase 1)Study completedNCT05098054
What this trial is testing

Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Takeda 36
Early research (Phase 1)Study completedNCT01600976
What this trial is testing

Assess Safety and Pharmacokinetics of Telaprevir in Patients With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Janssen Infectious Diseases BVBA 24
Early research (Phase 1)Study completedNCT06340347
What this trial is testing

Learn How the Body Processes the Study Medicine Called Osivelotor (PF-07940367) in People With Loss of Liver Function

Who this might be right for
Liver Diseases
Pfizer 8
Early research (Phase 1)Study completedNCT01271387
What this trial is testing

Pharmacokinetics of Tasimelteon in Subjects With Mild or Moderate Hepatic Impairment

Who this might be right for
Hepatic Impairment
Vanda Pharmaceuticals 29
Early research (Phase 1)Study completedNCT01670734
What this trial is testing

Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjects

Who this might be right for
Hypercholesterolemia
Sanofi 25
Early research (Phase 1)Study completedNCT06048302
What this trial is testing

PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy
NewAmsterdam Pharma 18
Early research (Phase 1)Study completedNCT07025551
What this trial is testing

A Clinical Study of MK-8527 in Participants With Mild and Moderate Hepatic Impairment (MK-8527-015)

Who this might be right for
Hepatic ImpairmentHealthy Participants
Merck Sharp & Dohme LLC 18
Early research (Phase 1)Ended earlyNCT05209295
What this trial is testing

Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Who this might be right for
Hepatic InsufficiencyNeoplasms
Bristol-Myers Squibb 2
Early research (Phase 1)Study completedNCT01154114
What this trial is testing

Study to Evaluate Darapladib in Moderately Hepatically Impaired Subjects

Who this might be right for
Atherosclerosis
GlaxoSmithKline 24
Early research (Phase 1)Study completedNCT04482270
What this trial is testing

Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Astellas Pharma Global Development, Inc. 26
Early research (Phase 1)Study completedNCT06952634
What this trial is testing

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Who this might be right for
Hepatic Impairment
Alumis Inc 32
Early research (Phase 1)Study completedNCT00698464
What this trial is testing

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Who this might be right for
Hepatic CirrhosisAlcoholism
Novartis Pharmaceuticals 34
Early research (Phase 1)Ended earlyNCT04241835
What this trial is testing

Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Who this might be right for
Hepatic ImpairmentAdvanced Malignant Solid Tumor
Epizyme, Inc. 18
Early research (Phase 1)Study completedNCT01126086
What this trial is testing

Pharmacokinetic, Pharmacodynamic and Tolerability Study of Otamixaban in Patients With Mild and Moderate Hepatic Impairment

Who this might be right for
Hepatic Impairment
Sanofi 25
Early research (Phase 1)Study completedNCT06961643
What this trial is testing

Investigation of Pharmacokinetics and Safety of HRS-7535 in Subjects With Hepatic Impairment and Normal Hepatic Function

Who this might be right for
Diabetes Mellitus
Shandong Suncadia Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT01817985
What this trial is testing

Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
Chronic Hepatitis C
Gilead Sciences 33
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