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Results for “Moderately to Severely Active Ulcerative Colitis”

189 trials

Showing 20 of 189 results

Testing effectiveness (Phase 2)Study completedNCT04996797
What this trial is testing

Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)

Who this might be right for
Ulcerative Colitis
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 178
Large-scale testing (Phase 3)Study completedNCT03524092
What this trial is testing

A Maintenance Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Eli Lilly and Company 1,328
Large-scale testing (Phase 3)Ended earlyNCT05644665
What this trial is testing

Evaluate Efficacy and Long-term Safety of Oral Ozanimod in Chinese Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis
Bristol-Myers Squibb 131
Testing effectiveness (Phase 2)Looking for participantsNCT07229950
What this trial is testing

Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inflammatory Bowel Disease

Who this might be right for
Adult Patients With Moderately to Severely Active Ulcerative Colitis
Shandong Suncadia Medicine Co., Ltd. 48
Large-scale testing (Phase 3)Study completedNCT03945188
What this trial is testing

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Arena Pharmaceuticals 433
Large-scale testing (Phase 3)Study completedNCT03518086
What this trial is testing

An Induction Study of Mirikizumab in Participants With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)

Who this might be right for
Ulcerative Colitis
Eli Lilly and Company 1,281
Testing effectiveness (Phase 2)Active Not RecruitingNCT07035041
What this trial is testing

D-2570 in Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
UC - Ulcerative ColitisModerately to Severely Active Ulcerative Colitis
InventisBio Co., Ltd 120
Large-scale testing (Phase 3)Study completedNCT05507203
What this trial is testing

ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Who this might be right for
Ulcerative Colitis
Abivax S.A. 639
Early research (Phase 1)UnknownNCT05743010
What this trial is testing

A Phase 1b Study to Evaluate APL-1401 in Patients With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Jiangsu Yahong Meditech Co., Ltd aka Asieris 36
Testing effectiveness (Phase 2)Looking for participantsNCT07507513
What this trial is testing

The Purpose of This Study is to Evaluate the Efficacy and Safety of 627 in the Treatment of UC

Who this might be right for
Ulcerative Colitis (UC)
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 288
Large-scale testing (Phase 3)Looking for participantsNCT07196748
What this trial is testing

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 882
Large-scale testing (Phase 3)Study completedNCT03482635
What this trial is testing

BI655130 (SPESOLIMAB) Induction Treatment in Patients With Moderate-to-severe Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Boehringer Ingelheim 98
Testing effectiveness (Phase 2)WithdrawnNCT02913508
What this trial is testing

Vedolizumab Subcutaneous (SC) Versus Intravenous (IV) in Ulcerative Colitis or Crohn's Disease

Who this might be right for
Ulcerative ColitisCrohn's Disease
Takeda
Large-scale testing (Phase 3)Study completedNCT02136069
What this trial is testing

A Study Comparing the Efficacy and Safety of Etrolizumab to Infliximab in Participants With Moderate to Severe Ulcerative Colitis Who Are Naïve to Tumor Necrosis Factor (TNF) Inhibitors

Who this might be right for
Ulcerative Colitis
Hoffmann-La Roche 397
Large-scale testing (Phase 3)Study completedNCT01458951
What this trial is testing

Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 547
Testing effectiveness (Phase 2)Study completedNCT06049017
What this trial is testing

JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 252
Large-scale testing (Phase 3)Study completedNCT02819635
What this trial is testing

Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Who this might be right for
Ulcerative Colitis (UC)
AbbVie 1,302
Testing effectiveness (Phase 2)Study completedNCT00572585
What this trial is testing

Efficacy, Safety and Tolerability of AEB071 in Patients With Active, Moderate to Severe Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Novartis Pharmaceuticals 60
Not applicableUnknownNCT06469424
What this trial is testing

An Active Surveillance, Post-Authorization Study to Characterize the Safety of Tofacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in the Real-World Setting Using Data From the United Registries for Clinical Assessment and Research (UR-CARE) in the European Union (EU)

Who this might be right for
Ulcerative Colitis
Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa 104
Large-scale testing (Phase 3)Active Not RecruitingNCT03596645
What this trial is testing

Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 84
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