Large-scale testing (Phase 3)Study completedNCT03491462What this trial is testingArimoclomol in Amyotropic Lateral SclerosisWho this might be right forAmyotrophic Lateral Sclerosis ZevraDenmark 245
Very early researchStudy completedNCT02710162What this trial is testingAccurate Screening Tools for Dysphagia in Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis University of Florida 21
Testing effectiveness (Phase 2)Ended earlyNCT03334786What this trial is testingStudy to Evaluate Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Appendicular Muscle in Adult Subjects With ALSWho this might be right forAmyotrophic Lateral SclerosisFasciculation Flex Pharma, Inc. 3
Not applicableLooking for participantsNCT04885374What this trial is testingChina Amyotrophic Lateral Sclerosis Registry of Patients With Traditional Chinese MedicineWho this might be right forAmyotrophic Lateral Sclerosis Dongzhimen Hospital, Beijing 2,000
Testing effectiveness (Phase 2)Study completedNCT01089010What this trial is testingCK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Cytokinetics 67
Not applicableStudy completedNCT02611674What this trial is testingMethodology Study of Novel Outcome Measures to Assess Progression of ALSWho this might be right forAmyotrophic Lateral Sclerosis Biogen 138
Testing effectiveness (Phase 2)Study completedNCT05039268What this trial is testing3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Macquarie University, Australia 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT05218668What this trial is testingRho Kinase Inhibitor in Amyotrophic Lateral Sclerosis (REAL)Who this might be right forAmyotrophic Lateral Sclerosis Woolsey Pharmaceuticals 40
Not applicableLooking for participantsNCT06820008What this trial is testingMeasurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS ProjectWho this might be right forAmyotrophic Lateral SclerosisMotor Neurone Disease University of Dublin, Trinity College 60
Large-scale testing (Phase 3)Not Yet RecruitingNCT07321860What this trial is testingThis Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic SignalingWho this might be right forALS (Amyotrophic Lateral Sclerosis) Gipfel Life Sciences GmbH 60
Not applicableLooking for participantsNCT07491484What this trial is testingImpact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealthWho this might be right forAmyotrophic Lateral SclerosisMotor Neuron Disease TidalHealth, Inc. 30
Not applicableLooking for participantsNCT04097158What this trial is testingBiomarkers in Different Types of Amyotrophic Lateral Sclerosis (ALS) Patients Being Treated With EdaravoneWho this might be right forAmyotrophic Lateral Sclerosis Loma Linda University 160
Testing effectiveness (Phase 2)Ended earlyNCT04066244What this trial is testingStudy of Safety and Proof of the Mechanism of BLZ945 in ALS PatientsWho this might be right forAmyotrophic Lateral Sclerosis Novartis Pharmaceuticals 28
Early research (Phase 1)Active Not RecruitingNCT05306457What this trial is testingCNS10-NPC-GDNF Delivered to the Motor Cortex for ALSWho this might be right forAmyotrophic Lateral Sclerosis Cedars-Sinai Medical Center 16
Not applicableStudy completedNCT00714636What this trial is testingCerebrospinal Fluid RepositoryWho this might be right forAmyotrophic Lateral SclerosisCerebrospinal FluidNeurodegenerative Disease+1 more Drexel University College of Medicine 11
Not applicableActive Not RecruitingNCT07143656What this trial is testingAmyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational RegistryWho this might be right forAmyotrophic Lateral Sclerosis (ALS)Amyotrophic Lateral Sclerosis &Amp; Other Neuromuscular Disorders Biocells Medical 36
Not applicableStudy completedNCT00716131What this trial is testingAmyotrophic Lateral Sclerosis (ALS) Tissue Donation ProgramWho this might be right forAmyotrophic Lateral SclerosisNeurodegenerative DiseaseMotor Neuron Disease Drexel University College of Medicine 205
Not applicableStudy completedNCT00956501What this trial is testingAssessment of Postural Orientation and Equilibrium In Early Amyotrophic Lateral Sclerosis (ALS)Who this might be right forAmyotrophic Lateral Sclerosis Wake Forest University Health Sciences 35
Large-scale testing (Phase 3)Looking for participantsNCT03127267What this trial is testingEfficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS PatientsWho this might be right forAmyotrophic Lateral Sclerosis AB Science 495
Early research (Phase 1)Study completedNCT03241784What this trial is testingPh1 T-Regulatory Cells in Amyotrophic Lateral SclerosisWho this might be right forALS (Amyotrophic Lateral Sclerosis) The Methodist Hospital Research Institute 3