Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Mutation, Point”

26 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 26 results

Early research (Phase 1)Ended earlyNCT01804530
What this trial is testing

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorTumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsTenosynovial Giant Cell Tumor
Plexxikon 59
Testing effectiveness (Phase 2)Study completedNCT00831974
What this trial is testing

Efficacy of AB1010 in Patients With Systemic Indolent Mastocytosis

Who this might be right for
Mastocytosis
AB Science 23
Early research (Phase 1)Not Yet RecruitingNCT07383506
What this trial is testing

Mutant Selective-Inhibitor (CGT6297), in Patients With Advanced Solid Tumors

Who this might be right for
PIK3CA MutationsAdvanced Solid Tumors, AdultEndometrial Cancer+2 more
Cogent Biosciences, Inc. 90
Not applicableStudy completedNCT00959504
What this trial is testing

Detection of Factor V Leiden G1691A and Factor II (Prothrombin) G20210A Point Mutations in DNA

Who this might be right for
Detection and Genotyping of Factor V and Factor II Point Mutations
Illumina, Inc. 275
Testing effectiveness (Phase 2)Ended earlyNCT04534283
What this trial is testing

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

Who this might be right for
CancerCancer MetastaticBRAF V600E+4 more
Anita Turk 16
Testing effectiveness (Phase 2)Study completedNCT01266369
What this trial is testing

Masitinib in Patients With Mastocytosis With Handicap and Bearing the D816V Mutation

Who this might be right for
Mastocytosis
AB Science 21
Not applicableUnknownNCT02881333
What this trial is testing

Various Type of Genetic Events in Patients With Intellectual Disability

Who this might be right for
Intellectual Disability
University Hospital, Strasbourg, France 30
Not applicableLooking for participantsNCT01532791
What this trial is testing

Natural History Study - Mitochondrial Disease

Who this might be right for
MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Columbia University 300
Not applicableUnknownNCT03566745
What this trial is testing

Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease

Who this might be right for
Mutation, Point
Hillel Yaffe Medical Center 14
Post-approval studies (Phase 4)Study completedNCT01453036
What this trial is testing

Clarithromycin Resistant Tailored Therapy

Who this might be right for
Peptic UlcerHelicobacter Pylori Infection
Jin Il Kim 924
Testing effectiveness (Phase 2)UnknownNCT01955421
What this trial is testing

Erlotinib 100mg qd Versus Gefitinib 250mg qd for EGFR Mutant Nsclc

Who this might be right for
Advanced Stage Non Small Cell Lung Cancer
Sun Yat-sen University 224
Post-approval studies (Phase 4)Study completedNCT03130452
What this trial is testing

Helicobacter Pylori Eradication Study

Who this might be right for
Helicobacter Pylori Infection
Inje University 423
Testing effectiveness (Phase 2)UnknownNCT00457314
What this trial is testing

The Effects of Exercise Versus Inactivity on People With Mitochondrial Muscle Disease

Who this might be right for
Mitochondrial Myopathy
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 50
Not applicableUnknownNCT01695512
What this trial is testing

Diagnostic Study of Combined Biomnarker Testing in Bronchoalveolar Lavage Samples of Immunocompromised Patients

Who this might be right for
Invasive AspergillosisAcute LeukemiaBiomarkers+1 more
Heidelberg University 200
Testing effectiveness (Phase 2)Looking for participantsNCT06782932
What this trial is testing

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Testing effectiveness (Phase 2)Ended earlyNCT02634827
What this trial is testing

Midostaurin and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia and FLT3 Mutation

Who this might be right for
Acute Myeloid Leukemia With FLT3/ITD MutationAcute Myeloid Leukemia With Gene MutationsFLT3 Tyrosine Kinase Domain Point Mutation+2 more
Mayo Clinic 1
Testing effectiveness (Phase 2)UnknownNCT00068913
What this trial is testing

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 35
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Not applicableUnknownNCT04163159
What this trial is testing

Genetic Markers of Circulating Tumor DNA for Monitoring Breast Cancer Patients in Costa Rica

Who this might be right for
Metastatic Breast CancerMutation, Point
Universidad de Costa Rica 25
Not applicableUnknownNCT02359747
What this trial is testing

Analysis of Human Genomic DNA in Embryo's Culture Media

Who this might be right for
Single-Gene Disease
Cervesi Hospital, Cattolica, Italy 100
Load More Results