Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Mutation Abnormality”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT05367778
What this trial is testing

Phase 1/2 Study of HS-10370 in Patients with Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Jiangsu Hansoh Pharmaceutical Co., Ltd. 176
Testing effectiveness (Phase 2)Active Not RecruitingNCT04233346
What this trial is testing

The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation

Who this might be right for
Chronic Myeloid LeukemiaAcute Lymphoblastic Leukemia
Otsuka Beijing Research Institute 93
Early research (Phase 1)Ended earlyNCT05622058
What this trial is testing

ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer

Who this might be right for
Prevention of Chemotherapy-induced Myelosuppression
Aileron Therapeutics, Inc. 6
Early research (Phase 1)Active Not RecruitingNCT04111458
What this trial is testing

Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)

Who this might be right for
Solid Tumors, KRAS Mutation; SOS1
Boehringer Ingelheim 71
Large-scale testing (Phase 3)Study completedNCT05033080
What this trial is testing

VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 435
Testing effectiveness (Phase 2)Looking for participantsNCT05886920
What this trial is testing

D3S-002 as Monotherapy or Combination Therapy in Adult Subjects With Advanced Solid Tumors With MAPK Pathway Mutations

Who this might be right for
Advanced Solid Tumors With MAPK Pathway Mutations
D3 Bio (Wuxi) Co., Ltd 67
Not applicableStudy completedNCT06534424
What this trial is testing

Clinical Impact of Enhanced Risk Assessments in Women With a BRCA1/2 Mutation, CARE Study

Who this might be right for
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome
Ohio State University Comprehensive Cancer Center 152
Not applicableLooking for participantsNCT06716580
What this trial is testing

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

Who this might be right for
Lung CancerEGFR Gene Mutation
Dana-Farber Cancer Institute 1,000
Testing effectiveness (Phase 2)Study completedNCT00580112
What this trial is testing

An Efficacy Study of Trabectedin in the Treatment of Participants With Specific Subtypes of Metastatic Breast Cancer

Who this might be right for
Breast Neoplasms
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 127
Testing effectiveness (Phase 2)Study completedNCT01266967
What this trial is testing

GSK2118436 in BRAF Mutant Metastatic Melanoma to the Brain

Who this might be right for
Melanoma and Brain Metastases
GlaxoSmithKline 172
Not applicableUnknownNCT02284633
What this trial is testing

Blood Sample Monitoring of Patients With EGFR Mutated Lung Cancer

Who this might be right for
Lung Neoplasms
Aarhus University Hospital 250
Not applicableStudy completedNCT02663232
What this trial is testing

Study to Analyze Mutations in V600 BRAF Oncogen in Participants With Metastatic Melanoma

Who this might be right for
Metastatic Cancers
Hoffmann-La Roche 264
Not applicableStudy completedNCT02884063
What this trial is testing

Utilizing Free DNA in Embryo Culture for PGT

Who this might be right for
Chromosome AbnormalitiesGenetic Diseases, InbornMutation
Al Baraka Fertility Hospital 100
Testing effectiveness (Phase 2)Study completedNCT03977584
What this trial is testing

Tau Positron Emission Tomography (PET) Longitudinal Substudy Associated With: Study of Crenezumab Versus Placebo in Preclinical Presenilin1 (PSEN1) E280A Mutation Carriers in the Treatment of Autosomal-Dominant Alzheimer's Disease

Who this might be right for
Alzheimer Disease
Hoffmann-La Roche 114
Early research (Phase 1)Study completedNCT02027961
What this trial is testing

Phase 1 Safety and Tolerability of MEDI4736 in Combination With Dabrafenib and Trametinib or With Trametinib Alone

Who this might be right for
Melanoma
MedImmune LLC 68
Large-scale testing (Phase 3)Study completedNCT01464086
What this trial is testing

LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)

Who this might be right for
Li Fraumeni Syndrome
Gustave Roussy, Cancer Campus, Grand Paris 107
Testing effectiveness (Phase 2)UnknownNCT00616499
What this trial is testing

Gefitinib in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
Yonsei University 35
Not applicableUnknownNCT04218006
What this trial is testing

A Study on the Prevalence of Mutation of Cerebrotendinous Xanthomatosis (CTX)

Who this might be right for
Xanthomatosis, Cerebrotendinous
TRPHARM 800
Testing effectiveness (Phase 2)Ended earlyNCT01264081
What this trial is testing

Lapatinib in Stage IV Melanoma With ERBB4 Mutations

Who this might be right for
Malignant Melanoma
National Cancer Institute (NCI) 34
Not applicableLooking for participantsNCT05424692
What this trial is testing

Drug Sensitivity Detection of Micro Tumor (PTC) to Guide Postoperative Adjuvant Treatment Strategy of Colorectal Cancer

Who this might be right for
Colon CancerRectal CancerChemotherapy Effect+2 more
Peking Union Medical College Hospital 200
Next Page