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Results for “Myelodysplastic Syndromes, Adult”

669 trials

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Showing 20 of 669 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07283900
What this trial is testing

Ascorbate in Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic Syndromes
Prajwal Dhakal 38
Testing effectiveness (Phase 2)Study completedNCT01497145
What this trial is testing

A Clinical Study of KRN321 in Adult Subjects With Myelodysplastic Syndrome

Who this might be right for
MDS
Kyowa Kirin Co., Ltd. 45
Early research (Phase 1)Study completedNCT01757639
What this trial is testing

Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome+3 more
National Cancer Institute (NCI) 42
Large-scale testing (Phase 3)Looking for participantsNCT06499285
What this trial is testing

Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Who this might be right for
Myelodysplastic Syndromes
Takeda 225
Testing effectiveness (Phase 2)Active Not RecruitingNCT06001385
What this trial is testing

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAcute Leukemia+8 more
Center for International Blood and Marrow Transplant Research 313
Early research (Phase 1)Looking for participantsNCT07256301
What this trial is testing

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
PNH - Paroxysmal Nocturnal Hemoglobinuria
Shanghai Lanyi Therapeutics Co., Ltd. 24
Large-scale testing (Phase 3)Study completedNCT06593938
What this trial is testing

Evaluate the Efficacy and Safety of Oral HRS-5965 in Adult Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 76
Early research (Phase 1)Ended earlyNCT00996359
What this trial is testing

Partially HLA-Matched Irradiated Allogeneic Cellular Therapy After Reduced Intensity Total Body Irradiation

Who this might be right for
LeukemiaLymphomaMultiple Myeloma and Plasma Cell Neoplasm+1 more
University of Medicine and Dentistry of New Jersey 4
Testing effectiveness (Phase 2)Looking for participantsNCT06802315
What this trial is testing

Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia, Relapsed, AdultAcute Myeloid Leukemia RefractoryChronic Myeloid Leukemia - Accelerated Phase+1 more
University of Illinois at Chicago
Testing effectiveness (Phase 2)Looking for participantsNCT03779854
What this trial is testing

Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

Who this might be right for
Acute Biphenotypic LeukemiaAcute LeukemiaAcute Leukemia of Ambiguous Lineage+14 more
Fred Hutchinson Cancer Center 68
Large-scale testing (Phase 3)Looking for participantsNCT06829472
What this trial is testing

Conditioning Regimen of Melphalan-busulfan and Fludarabine: a Randomized Study of Different Dose of Melphalan

Who this might be right for
ToxicitiesSurvivorship
Shanghai Jiao Tong University School of Medicine 120
Early research (Phase 1)Study completedNCT00004232
What this trial is testing

Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Who this might be right for
Chronic Myeloproliferative DisordersGraft Versus Host DiseaseLeukemia+4 more
Northwestern University
Testing effectiveness (Phase 2)Study completedNCT01083706
What this trial is testing

Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+9 more
Fred Hutchinson Cancer Center 43
Early research (Phase 1)Study completedNCT00077558
What this trial is testing

3-AP Followed By Fludarabine In Treating Patients With Relapsed or Refractory Acute or Chronic Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Looking for participantsNCT05601726
What this trial is testing

First-in-human Study Aiming to Characterize the Safety, Tolerability, Pharmacokinetic and Preliminary Signs of Activity of ABD-3001 in Refractory or Relapsed AML and High Risk MDS Adult Patients

Who this might be right for
Acute Myeloid Leukemia, AdultMyelodysplastic Syndromes
Advanced BioDesign 36
Testing effectiveness (Phase 2)Study completedNCT00064311
What this trial is testing

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

Who this might be right for
Breast CancerChronic Myeloproliferative DisordersGestational Trophoblastic Tumor+9 more
National Institutes of Health Clinical Center (CC)
Early research (Phase 1)Study completedNCT00278330
What this trial is testing

Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Adult Acute Myeloid Leukemia+4 more
National Cancer Institute (NCI) 24
Not applicableNo Longer AvailableNCT04484363
What this trial is testing

Expanded Access Program With Pevonedistat (Given With Azacitidine) for Adults With Higher-risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Takeda
Testing effectiveness (Phase 2)Ended earlyNCT00052598
What this trial is testing

Therapeutic Allogeneic Lymphocytes and Aldesleukin in Treating Patients With High-Risk or Recurrent Myeloid Leukemia After Undergoing Donor Stem Cell Transplant

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities+12 more
Fred Hutchinson Cancer Center 7
Testing effectiveness (Phase 2)UnknownNCT00008164
What this trial is testing

Umbilical Cord Blood and Placental Blood Transplantation in Treating Patients With Hematologic Cancer or Aplastic Anemia

Who this might be right for
Childhood Langerhans Cell HistiocytosisLeukemiaLymphoma+3 more
Herbert Irving Comprehensive Cancer Center 30
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